Neotrexate Injection

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Glaxo SmithKline Pharmaceuticals Ltd

Composition for Neotrexate 50mg Injection

iconPrescription Required
Potentiallyunsafewith
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Alcohol
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Pregnancy
50.76
2 ml in 1 vial
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Medicine Overview of Neotrexate Injection

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Uses of Neotrexate Injection

Neotrexate Injection is used in the treatment of blood cancer, bone cancer, non-Hodgkin lymphoma (NHL), breast cancer, lung cancer, head and neck cancer, cervical cancer, ovarian cancer and testicular cancer.
It is also used in rheumatoid arthritis, psoriasis (silvery scaly skin rash) and ectopic pregnancy at low doses.
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Side effects of Neotrexate Injection

Common

Nausea, Vomiting, Loss of appetite, Dyspepsia, Abdominal pain, Increased liver enzymes, Stomatitis (Inflammation of the mouth).

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How to use Neotrexate Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Neotrexate Injection works

Neotrexate Injection is an anticancer and immunosuppressive medication. It works in cancer by slowing the growth of cancer cells by blocking building blocks that cancer cells need to grow. It also works in autoimmune disease by decreasing the activity of body's immune system and prevents the body from attacking itself.

In Depth Information on Neotrexate Injection

Expert advice for Neotrexate Injection

  • For autoimmune diseases, Neotrexate is taken by mouth, once a week (not every day) on the same day each week. It can take 2 to 3 weeks for Neotrexate to start working.
  • Notify your doctor immediately if you develop a sore throat or fever (infection), bruising or bleeding, nausea, abdominal pain or dark urine or difficulty breathing.
  • Your doctor may ask to get complete blood count (CBC), kidney function test (KFT) and liver function test (LFT) before starting treatment and thereafter also.
  • Neotrexate may harm your unborn babies or cause miscarriages. You and your partner should avoid conception (becoming pregnant or fathering children) for at least three months after your treatment with Neotrexate has stopped.
  • Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
  • Inform your doctor if you have ever been diagnosed with kidney or liver problems.
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Neotrexate Injection related warnings
Special precautions for Neotrexate Injection
Alcohol
CAUTION
Taking Methotrxate with alcohol increases the risk of liver damage.
Pregnancy
CAUTION
Neotrexate Injection is highly unsafe to use during pregnancy.

Human and animal studies have shown significant adverse effects on the foetus. Please consult your doctor.
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Lactation
UNSAFE
Neotrexate Injection is unsafe to use during lactation. Dat
a suggests that the drug may cause toxicity to the baby, or the mother is suffering from a condition in which breastfeeding is not advisable.
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Driving
Neotrexate Injection may make you feel dizzy, drowsy or affe
ct your vision. Do not drive until your vision is clear.
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Kidney
CAUTION
Neotrexate Injection should be used with caution in patients with kidney disease. Dose adjustment of Neotrexate Injection may be needed. Please consult your doctor.

Regular monitoring of kidney function test is advised while you are taking this medicine.
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Liver
CAUTION
Neotrexate Injection should be used with caution in patients with liver disease. Dose adjustment of Neotrexate Injection may be needed. Please consult your doctor.

Use of Neotrexate Injection is not recommended in patients with severe liver disease.
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Severely interacts with other drugs like
Dexadran 4mg Injection, Decamycin 4mg Injection, Walacort 0.5mg Tablet, Pericort 4mg Tablet

Patient Concerns

Frequently asked questions about Neotrexate Injection

Frequently asked questions about Methotrexate

Neotrexate is not a steroid or non-steroidal anti-inflammatory drugs (NSAIDs). It is a chemotherapy drug used in the treatment of different types of cancer and it is also a disease-modifying antirheumatic drugs (DMARD) used in the treatment of severe rheumatoid arthritis
Neotrexate belongs to a class of drugs known as antimetabolites used to treat severe, uncontrolled psoriasis. Neotrexate is safe if used at prescribed doses for the prescribed duration as advised by your doctor
Neotrexate is safe if used at prescribed doses for the prescribed duration as advised by your doctor
Q. Is Neotrexate a narcotic/ biologic drug?
No. Neotrexate is not a narcotic drug/ biologic drug
Q. Does Neotrexate cause weight gain/ weight loss/ fatigue/ diarrhea/ acne/ mood swings/ nausea/ infertility?
Neotrexate may cause side effects such as fatigue, diarrhea, acne, mood swings, nausea, and infertility. But it has no known effect on weight gain/ weight loss
Q. Does Neotrexate cause cancer?
Neotrexate belongs to a class of drugs known as antimetabolites. It is used for the treatment of wide range of cancer and tumors. However it may increase the risk of secondary malignancies such as melanoma and other cancers.
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Substitutes for Neotrexate Injection

BIOTREXATE 50 MG INJECTION
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₹24.38/ml of Injection
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