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Nefazor XR 500 Tablet

Prescription Required
SALT COMPOSITION
Storage
Store at room temperature (10-30°C)

Introduction

Nefazor XR 500 Tablet is a medicine used for the management of angina (heart-related chest pain). It helps to prevent new attacks of angina, but it does not stop an acute attack, once it has started. It relieves chest pain by making the heart work more efficiently.

Nefazor XR 500 Tablet should be taken in the dose as advised by your doctor, at the same time each day. It should be taken with food to avoid stomach upset. Your doctor will decide how often you should take this medicine. This may change from time to time depending on how well it is working. You should take this medicine regularly to get the most benefit, even if you feel fine. It is preventing future harm. If you stop taking it, your chest pain may come back.

You can improve the health of your heart by making some lifestyle changes such as quitting smoking, cutting down on alcohol, eating well, taking regular exercise and managing stress. Some common side effects of this medicine include nausea, vomiting, headache, dizziness, constipation, and weakness. Talk to your doctor if these bother you or do not go away.

This is not suitable for some people. Tell your doctor if you are suffering from any liver or kidney problems. Also let your doctor know all other medications you are using as some may affect, or be affected by this medicine. This medicine is not usually recommended during pregnancy or breastfeeding.

Uses of Nefazor Tablet ER

Side effects of Nefazor Tablet ER

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Nefazor

  • Nausea
  • Vomiting
  • Headache
  • Dizziness
  • Constipation
  • Weakness

How to use Nefazor Tablet ER

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nefazor XR 500 Tablet is to be taken with food.

How Nefazor Tablet ER works

Nefazor XR 500 Tablet is an anti-anginal medication. It works by decreasing the oxygen requirement of the heart by relaxing heart muscle.

Safety Advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Nefazor XR 500 Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Nefazor XR 500 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Nefazor XR 500 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Nefazor XR 500 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CAUTION
Nefazor XR 500 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Nefazor XR 500 Tablet may be needed. Please consult your doctor.
Use of Nefazor XR 500 Tablet is not recommended in patients with severe kidney disease.
Liver
CAUTION
Nefazor XR 500 Tablet should be used with caution in patients with liver disease. Dose adjustment of Nefazor XR 500 Tablet may be needed. Please consult your doctor.
Use of Nefazor XR 500 Tablet is not recommended in patients with moderate to severe liver disease.

What if you forget to take Nefazor Tablet ER?

If you miss a dose of Nefazor XR 500 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
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Quick Tips

  • It should be taken with food to avoid stomach upset.
  • It improves HbA1c and blood sugar levels in diabetes patients.
  • It may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
  • Notify your doctor if you are taking any other medications along with Nefazor XR 500 Tablet
  • It may produce changes in the ECG (QTc interval prolongation). It is recommended to get an ECG done within 1 to 2 weeks of starting the medication.

Fact Box

Chemical Class
Acetanilide & piperazine derivative
Habit Forming
No

Patient Concerns

arrow
What is heart attack? When heart attack coming?
Dr. Nabajit Talukdar
Cardiology
Related to chest pain angina commonly
Chest pain headache vetrigo Angina pain
Dr. Nabajit Talukdar
Cardiology
Get echo n ECG done
arrow
Do you have any questions related to Nefazor XR 500 Tablet ?

FAQs

Q. What are the serious side effects of Nefazor XR 500 Tablet?

Nefazor XR 500 Tablet may cause changes in electrical activity of heart which is known as QT prolongation. Your doctor may get regular tests done to check the electrical activity of your heart. Tell your doctor right away if you feel faint, lightheaded or if your heart starts beating irregularly or fast, as these may be symptoms of QT prolongation. Nefazor XR 500 Tablet may also cause kidney failure in patients who already have kidney problems. Therefore, your doctor may need to do tests to check how your kidneys are working.

Q. I started taking Nefazor XR 500 Tablet about a week ago. Now I have noticed that my urine has become very dark though I am taking plenty of fluids. Is there anything to worry about?

Urine discoloration could be because of Nefazor XR 500 Tablet. You need not worry if you do not have any other symptoms. However, if it still bothers you, you can talk to your doctor who will advise you further.

Q. In case I accidentally take excess of Nefazor XR 500 Tablet, what will happen?

Excess of Nefazor XR 500 Tablet can cause nausea, vomiting, lightheadedness, double vision, tiredness, severe tremor, confusion, hallucinations, difficulty in speaking and walking and you can even faint. If you have taken excess of Nefazor XR 500 Tablet by mistake, call your doctor right away or seek emergency medical care in a nearby hospital.

Q. Is it safe to take Nefazor XR 500 Tablet if I am already taking metoprolol?

Yes, it is safe to take the Nefazor XR 500 Tablet and Metoprolol together. Nefazor XR 500 Tablet has minimal effect on blood pressure in patients of angina.

Q. I am a diabetic and am taking metformin. My doctor has prescribed Nefazor XR 500 Tablet, is it safe to take both together?

If you are taking metformin along with Nefazor XR 500 Tablet, you have to be careful since Nefazor XR 500 Tablet may increase the levels of metformin in the body which can lead to metformin toxicity. Talk to your doctor who will modify the dose of metformin.

Q. I have been taking simvastatin to keep my cholesterol levels in check. Can I take Nefazor XR 500 Tablet with it?

It is recommended not to take simvastatin and Nefazor XR 500 Tablet together because it may cause simvastatin toxicity which may lead to symptoms like muscle weakness and soreness, fatigue, decreased urination, etc. Let your doctor know that you are already taking simvastatin. If it is still necessary to take, then take it exactly as advised by the doctor.

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Disclaimer:

1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Opie LH, Horowitz JD. Nitrates and Newer Antianginals β-Blocking Agents. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. p. 56
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1200.
  3. Ranolazine. Wooburn Green, Buckinghamshire: A. Menarini Farmaceutica Internazionale SRL; 2008 [revised 22 Nov. 2018]. [Accessed 25 Jan. 2019] (online) Available from:External Link
  4. Ranolazine. Foster City, California: Gilead Sciences, Inc.; 2013. [Accessed 20 Mar. 2019] (online) Available from:External Link
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:External Link
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