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Minirin Melt 0.1mg Tablet 1
Minirin Melt 0.1mg Tablet 2

Minirin Melt 0.1mg Tablet

Desmopressin (0.1mg)
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Product Summary :

Minirin Melt 0.1mg Tablet contains desmopressin, a medicine used to treat diabetes insipidus and bed-wetting in children aged 5 years and older. It works by mimicking antidiuretic hormone, helping the kidneys retain water and reduce urine production. For diabetes insipidus, it is generally taken several times daily, while for bed-wetting, it is usually taken once at bedtime. A very common side effect of Minirin Melt 0.1mg Tablet is the headache. Excessive fluid intake during treatment can cause dangerously low sodium levels in the blood, so following fluid instructions is essential.


Written By Dr. Nikita Saini, MBA, MDS,
Reviewed By Dr. Dheeraj Kumar Sharma, PhD, M.Pharm,
Last updated on 20 Oct 2026 | 01:04 AM (IST)
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General Information

The content is shown in English
Minirin Melt 0.1mg Tablet 1
Minirin Melt 0.1mg Tablet 2

Product introduction

Minirin Melt 0.1mg Tablet is a medicine used in the treatment of diabetes insipidus and bed-wetting. It helps decrease the urge to urinate and helps resume a more normal lifestyle.

Minirin Melt 0.1mg Tablet can be taken on an empty stomach or after food. Your doctor will decide the dose and how often you should take it. You should use it regularly to get the most benefit from the medicine. Do not stop using the medicine even if you feel better unless the doctor tells you so.


Headache is a commonly reported side effect of Minirin Melt 0.1mg Tablet. It may cause mild to moderate pain or discomfort in the head. Getting adequate rest, staying hydrated, maintaining regular sleep patterns, and avoiding prolonged screen time may help relieve the discomfort. If the headache becomes severe, persists, or occurs frequently, consult your doctor for appropriate management.


Before using this medicine, inform your doctor if you have any problems with your heart, liver, or kidneys. You should also tell your doctor all the other medicines you are taking. Your doctor may monitor your blood glucose regularly while on treatment with this medicine.

Uses of Minirin Tablet

  • Diabetes insipidus : Used to treat a condition in which the body does not produce enough antidiuretic hormone, causing excessive urination and persistent thirst.
  • Bed-wetting : Used to treat primary nocturnal enuresis (bed-wetting) in children aged 5 years and older who have normal urine-concentrating ability.

Benefits of Minirin Tablet

Diabetes insipidus
Diabetes insipidus is a condition where the body loses too much water through frequent urination and excessive thirst, due to a hormone imbalance that affects how the kidneys manage fluids. Minirin Melt 0.1mg Tablet helps the body retain water by acting like the natural hormone (vasopressin) that regulates urine production. This reduces urine output and helps maintain normal hydration levels, relieving constant thirst and frequent urination.
Bed-wetting
Bed-wetting (nocturnal enuresis) is a common condition in children and sometimes adults, where involuntary urination happens during sleep, often due to the body producing more urine at night than the bladder can hold. Minirin Melt 0.1mg Tablet helps by reducing nighttime urine production, allowing better bladder control and fewer disruptions during sleep. This improves sleep quality and boosts confidence and comfort, especially in children.

Side effects of Minirin Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Minirin
  • Headache

How to use Minirin Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Minirin Melt 0.1mg Tablet may be taken with or without food.

How Minirin Tablet works

Minirin Melt 0.1mg Tablet is a synthetic form of vasopressin (natural hormone that balances water). It works by causing reabsorption of water from the kidneys which controls excessive thirst and urination in diabetes insipidus. It also helps decrease night-time urine production and bedwetting in children. In addition to these, it reduces bleeding episodes by promoting the release of blood clotting factors.

Dosage

For diabetes insipidus, it is generally taken three times daily, with the schedule adjusted according to urine output, thirst, fluid balance, and treatment response. For bed-wetting, it is usually taken once daily at bedtime. Treatment for bed-wetting is generally reviewed every three months, with a treatment-free period of at least one week to assess whether further treatment is necessary. Fluid intake must be carefully restricted around bedtime dosing for bed-wetting. Your doctor will determine the appropriate dose and duration for each condition.

All substitutes for Minirin Melt 0.1mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • You have been prescribed Minirin Melt 0.1mg Tablet for the treatment of diabetes insipidus and/or bed-wetting.
  • Limit the amount of fluids you drink with this medication.
  • Minirin Melt 0.1mg Tablet can cause low sodium levels in your body. Get regular blood tests done to monitor the levels.
  • Inform your doctor if you develop an infection, fever, diarrhea, or vomiting.
  • Talk to your doctor if you have sudden weight gain or swelling in your arms and legs that does not go away.
     

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Minirin Melt 0.1mg Tablet. Please consult your doctor.
Pregnancy

Pregnancy

SAFE IF PRESCRIBED
Minirin Melt 0.1mg Tablet is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.
Driving

Driving

SAFE
Minirin Melt 0.1mg Tablet does not usually affect your ability to drive.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Minirin Melt 0.1mg Tablet in patients with kidney disease. Please consult your doctor.
It cannot be used in case of severe renal failure.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Minirin Melt 0.1mg Tablet in patients with liver disease.

Interaction with drugs

Taking Minirin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate

Tolvaptan (Oral Route)

Your doctor may monitor your treatment and adjust the doses as per the observations.
Moderate

Aceclofenac (Oral Route)

Caution is advised when taking Desmopressin with Aceclofenac. Your doctor may monitor your sodium levels closely.
Moderate

Aceclofenac (Injection Route)

Caution is advised when taking Desmopressin with Aceclofenac. Your doctor may monitor your sodium levels closely.
Moderate

Aceclofenac (Oral Route)

Caution is advised when taking Desmopressin with Aceclofenac. Your doctor may monitor your sodium levels closely.
Moderate

Amitriptyline (Oral Route)

Caution is advised when taking Desmopressin with Amitriptyline. Your doctor may monitor your sodium levels closely.

Frequently asked questions

Follow all the instructions given by your doctor strictly. Restrict water intake after taking Minirin Melt 0.1mg Tablet as drinking too much water can lead to fluid overload, which is a serious side effect. Try not to swallow water while swimming.
Minirin Melt 0.1mg Tablet is usually prescribed for 3 months for bedwetting. After 3 months, your doctor will stop the medicine for a week to assess whether your child still needs Minirin Melt 0.1mg Tablet or not.
No, Minirin Melt 0.1mg Tablet does not cure bedwetting, but it helps control bedwetting. It works by replacing a hormone (vasopressin) that is normally produced in the body to help balance the amount of water and salt.
No, Minirin Melt 0.1mg Tablet itself does not cause weight gain. Minirin Melt 0.1mg Tablet may cause fluid overload which may in turn cause weight gain. Fluid overload is a serious side effect and you should immediately contact your doctor if you experience headache, nausea, vomiting, restlessness, tiredness, loss of appetite, sleepiness, confusion and muscle cramps.
No, Minirin Melt 0.1mg Tablet is not a diuretic. It is a hormone which helps lower urine output in patients with diabetes insipidus and helps control bedwetting in children. It works by reducing the amount of urine produced by the kidneys, thereby reducing the frequency of urination.

Fact Box

Chemical Class

Synthetic vasopressin analoguesues

Habit Forming

No

Therapeutic Class

HORMONES

Action Class

Vasopressin Analogues

References

  1. Reilly RF, Jackson EK. Regulation of Renal Function and Vascular Volume. In: Brunton LL, Chabner BA, Knollmann BC,12th ed. editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 712-14.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 375.
  3. Medlineplus. Desmopressin. [Accessed 04 Apr. 2019] (online) Available from:
  4. Desmopressin acetate. West Drayton, UK: Ferring Pharmaceuticals Ltd.; 2003 [revised Jun. 2011]. [Accessed 25 Jan. 2019] (online) Available from:
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 3 Apr. 2019] (online) Available from:
  6. Desmopressine. Holzkirchen, Germany: Hexal AG; 2023. [Accessed 19 Oct. 2026] (online). Available from:
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User feedback

Once A Day
97%
Alternate Day
3%
Bed-wetting
67%
Diabetes insipidus
25%
Others
8%
Average
47%
Excellent
40%
Poor
13%
Headache
33%
No Side Effect
33%
Nausea
17%
Stomach pain
17%
With food
33%
Empty stomach
33%
With or without food
33%
Expensive
78%
Average
22%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Ferring Pharmaceuticals
Address: K-28/1, ADDITIONAL MIDC , ANAND NAGAR , AMBERNATH - 421506 , INDIA

Vendor Details

Country of origin: Switzerland
A licensed vendor partner from your nearest location will deliver Minirin Melt 0.1mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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