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Milnone 10mg Injection

Milrinone (10mg)
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Milnone 10mg Injection is a medicine used for short-term treatment of heart failure. It is also used to treat patients with a poorly functioning heart after heart surgery. It makes the heart pump blood more efficiently.

Written By Dr. Mayank, Pharm.D,
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology,
Last updated on 07 Aug 2025 | 05:39 PM (IST)
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Gurgaon
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Aug, 2026

 
 
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General Information

The content is shown in English
Milnone 10mg Injection image
Milnone 10mg Injection image

Product introduction

It is administered under the supervision of a doctor. Your doctor will decide the dose and duration of the medicine for you. The doctor may closely monitor your blood pressure, heart rate, and ECG until you become stable. You should continue all your other medicines that are advised by the doctor for your long-term treatment even after this injection.

Common side effects of this medicine include hypotension, headaches,  arrhythmias, and tachycardia. Consult your doctor if these effects bother you. This medicine is used with caution for some people. Thus, you must inform the doctor if you are suffering from any kidney disease. Also, let your doctor know if you are pregnant or breastfeeding and about all the other medications that you are taking regularly.

Uses of Milnone Injection

Benefits of Milnone Injection

Heart Failure
Heart failure is a condition where the heart cannot pump blood effectively, leading to symptoms like shortness of breath, fatigue, and swelling in the legs or ankles. Milnone 10mg Injection helps improve the heart’s pumping ability and supports better blood flow throughout the body. It provides relief from symptoms, enhances physical activity, and stabilizes patients during critical stages, especially after heart surgery or during severe episodes, improving overall comfort and chances of recovery.

Side effects of Milnone Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Milnone
  • Hypotension (low blood pressure)
  • Headache
  • Arrhythmia (irregular heartbeats)
  • Tachycardia

How to use Milnone Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Milnone Injection works

Milnone 10mg Injection is a vasodilator. It increases the level of a chemical messenger (cAMP), which helps the smooth muscles to relax. Thus, dilates the blood vessels for better blood flow into the heart. It also has blood thinning property.

Quick tips

  • If mild burning or pain at the injection site bothers you consult with your doctor.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Milnone 10mg Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Milnone 10mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Milnone 10mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Milnone 10mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney

Kidney

CAUTION
Milnone 10mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Milnone 10mg Injection may be needed. Please consult your doctor.
Liver

Liver

SAFE IF PRESCRIBED
Milnone 10mg Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Milnone 10mg Injection may not be needed in these patients. Please consult your doctor.

Interaction with drugs

Taking Milnone with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate

Riociguat (Oral Route)

If concurrent use is essential, your doctor may monitor your blood pressure closely.
Mild

Aminophylline (Oral Route)

Talk to your doctor if you notice any unusual symptoms.
Mild

Aminophylline (Injection Route)

Talk to your doctor if you notice any unusual symptoms.

Fact Box

Chemical Class

Bipyridines and Oligopyridines Derivative

Habit Forming

No

Therapeutic Class

CARDIAC

Action Class

Phosphodiesterase-III Inhibitors

References

  1. Maron BA, Rocco TP. Pharmacotherapy of Congestive Heart Failure. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 805.
  2. Teerlink JR, Sliwa K, Opie LH. Heart Failure. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 181-83.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 921-22.
  4. Milrinone. Guildford, Surrey: SANOFI; 1989 [revised 19 Jun. 2018]. [Accessed 19 Mar. 2019] (online) Available from:
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Strathspey Labs Pvt Ltd
Address: K Raheja Platinum Sag Baug Off Andheri Kurla Marol Andheri East , Mumbai Maharashtra Marol Bazar- 400059

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Milnone 10mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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