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Midfast 5mg Injection

Written By Dr. Swati Mishra, BDS
Reviewed By Dr. Mekhala Chandra, MD, MBBS
Last updated on 14 Apr 2026 | 04:21 PM (IST)
Midfast 5mg Injection is used as a sedative or for conscious sedation before diagnostic or therapeutic procedures. It relieves anxiety and muscle tensions, thus making the person comfortable before investigations or minor surgical or dental procedures.
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General Information

The content is shown in English
Midfast 5mg Injection image
Midfast 5mg Injection image

Product introduction

Midfast 5mg Injection can be used for sedation in intensive care units and to obtain anesthesia in elderly people before undergoing any surgical procedure. This medicine is given as an injection under the supervision of a healthcare professional in a hospital setting. It may be administered by intravenous injection (injection into a vein) or by intravenous infusion (given by a drip into a vein).

The most common side effects of this medicine include hiccup, nausea, vomiting, cough, sedation, headache, drowsiness, and injection site reactions (pain, swelling, and redness). You should not drive or do anything that requires mental focus until you know how this medicine affects you. Inform your doctor if you are pregnant, planning to conceive, or breastfeeding before taking this medicine.

Benefits of Midfast Injection

Anesthesia
Midfast 5mg Injection is used to initiate anesthesia by calming the brain and inducing sleepiness. It helps reduce anxiety and muscle tension before full anesthesia, making the transition into unconsciousness smoother and more controlled.
Conscious sedation during diagnostic or therapeutic procedures
In diagnostic or therapeutic procedures, Midfast 5mg Injection helps reduce anxiety and discomfort while allowing patients to remain awake but relaxed. This makes procedures more tolerable and easier to perform safely.

Side effects of Midfast Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Midfast
  • Injection site reactions (pain, swelling, redness)
  • Vomiting
  • Injection site pain
  • Sleepiness
  • Apnea (absence of breathing)
  • Decreased respiratory rate
  • Nasal discomfort

How to use Midfast Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Midfast Injection works

Midfast 5mg Injection is a benzodiazepine. It works by increasing the action of a chemical messenger (GABA) which suppresses the abnormal and excessive activity of the nerve cells in the brain.

Quick tips

  • The addiction / habit-forming potential of this medicine is very high. Take it only as per the dose and duration advised by your doctor
  • It may cause dizziness. Do not drive or do anything that requires mental focus until you know how this medicine affects you.
  • Avoid consuming alcohol as it may increase dizziness and drowsiness.
  • Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
  • Do not stop taking medication suddenly without talking to your doctor as that may lead to nausea, anxiety, agitation, flu-like symptoms, sweating, tremor, and confusion.
  • The addiction / habit-forming potential of this medicine is very high. Take it only as per the dose and duration advised by your doctor
  • It may cause dizziness. Do not drive or do anything that requires mental focus until you know how this medicine affects you.
  • Avoid consuming alcohol as it may increase dizziness and drowsiness.
  • Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
  • Do not stop taking medication suddenly without talking to your doctor as that may lead to nausea, anxiety, agitation, flu-like symptoms, sweating, tremor, and confusion.

Safety advice

Alcohol

Alcohol

UNSAFE
Do not drink alcohol while you are taking this medicine. Midfast 5mg Injection may cause excessive drowsiness when taken with alcohol.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Midfast 5mg Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CAUTION
Midfast 5mg Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Midfast 5mg Injection should be used for short periods and sleepiness of the baby should be watched. The withdrawal of Midfast 5mg Injection should be gradual.
Driving

Driving

UNSAFE
Midfast 5mg Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Midfast 5mg Injection may make the patient sleepy, forgetful or affect their concentration or coordination. This may affect their ability to drive.
Kidney

Kidney

CAUTION
Midfast 5mg Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Midfast 5mg Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Midfast with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Tramadol (Injection Route)

If concurrent use is essential, watch out for symptoms of Midazolam side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Midazolam as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.
Severe

Clozapine (Oral Route)

If concurrent use is essential, watch out for symptoms such as dizziness, headaches, tremors, sleep disturbances or mood changes and consult your doctor if you experience them. They may adjust the doses as per the observations.
Severe

Tramadol (Oral Route)

If concurrent use is essential, watch out for symptoms of Midazolam side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Midazolam as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.
Severe

Morphine (Oral Route)

If concurrent use is essential, watch out for symptoms of Midazolam side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Midazolam as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.
Severe

Codeine (Oral Route)

If concurrent use is essential, watch out for symptoms of Midazolam side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Midazolam as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.

Frequently asked questions

Midfast 5mg Injection is safe if used at prescribed doses for the prescribed duration as advised by your doctor
Yes, Midfast 5mg Injection is a controlled substance
Yes, Midfast 5mg Injection a sedative medication used before and during diagnostic or surgical procedures either in combination with or without local anesthesia
No, Midfast 5mg Injection is not an opiate medication
Yes, Midfast 5mg Injection belongs to benzodiazepine class of sedative medication
No, Midfast 5mg Injection belongs to schedule 4. It has low potential for abuse
Versed is a brand (trade) name for Midfast 5mg Injection
No, Midfast 5mg Injection does not have any analgesic properties. It is used as a central nervous system depressant that slows brain activity, causes relaxation and induces sleep (anesthetic)
No, Midfast 5mg Injection does not make you high; it makes you sleepy as it is a central nervous system depressant that slows brain activity, causes relaxation and induces sleep
Yes, Midfast 5mg Injection causes retrograde amnesia (short term loss of memory)
No, Midfast 5mg Injection does not hasten death. Although it may be used to induce sleep and relive anxiety in terminally-ill patients not responding to other relevant medications
Yes, Midfast 5mg Injection crosses the placenta.

Fact Box

Chemical Class

Imidazo [1,5- a] [1,4] benzodiazepines

Habit Forming

Yes

Therapeutic Class

NEURO CNS

Action Class

Benzodiazepines

References

  1. Stahl SM, editor. Midazolam. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 431-33.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 914-15.
  3. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 20 Mar. 2019] (online) Available from:
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Samarth Life Sciences Pvt Ltd
Address: Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.

Vendor Details

Country of origin: India
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