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Midazolam

Written By Dr. Swati MishraReviewed By Dr. Rajeev Sharma
Last updated 13 Jun 2025 | 07:34 PM (UTC)

How Midazolam works

Midazolam is a benzodiazepine. It works by increasing the action of a chemical messenger (GABA) which suppresses the abnormal and excessive activity of the nerve cells in the brain.

Common side effects of Midazolam

Injection site pain, Sleepiness, Vomiting, Apnea (absence of breathing), Decreased respiratory rate, Nasal discomfort
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Expert advice for Midazolam

  • The addiction / habit-forming potential of this medicine is very high. Take it only as per the dose and duration advised by your doctor
  • It may cause dizziness. Do not drive or do anything that requires mental focus until you know how this medicine affects you.
  • Avoid consuming alcohol as it may increase dizziness and drowsiness.
  • Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
  • Do not stop taking medication suddenly without talking to your doctor as that may lead to nausea, anxiety, agitation, flu-like symptoms, sweating, tremor, and confusion.

Frequently asked questions for Midazolam

Midazolam is safe if used at prescribed doses for the prescribed duration as advised by your doctor
Yes, Midazolam is a controlled substance
Yes, Midazolam a sedative medication used before and during diagnostic or surgical procedures either in combination with or without local anesthesia
No, Midazolam is not an opiate medication
Yes, Midazolam belongs to benzodiazepine class of sedative medication
No, Midazolam belongs to schedule 4. It has low potential for abuse
Versed is a brand (trade) name for Midazolam
No, Midazolam does not have any analgesic properties. It is used as a central nervous system depressant that slows brain activity, causes relaxation and induces sleep (anesthetic)
No, Midazolam does not make you high; it makes you sleepy as it is a central nervous system depressant that slows brain activity, causes relaxation and induces sleep
Yes, Midazolam causes retrograde amnesia (short term loss of memory)
No, Midazolam does not hasten death. Although it may be used to induce sleep and relive anxiety in terminally-ill patients not responding to other relevant medications
Yes, Midazolam crosses the placenta.