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Midaspray

Written By Dr. Syeda Aafia, MBA, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 23 Apr 2026 | 11:59 PM (IST)
Midaspray is used for the rapid control of seizures. It acts quickly to calm abnormal brain activity, helping stop ongoing seizure episodes and providing timely relief in emergency situations.
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General Information

Contains

Midazolam (5mg)

Marketer

Intas Pharmaceuticals Ltd

Storage

Store below 30°C
The content is shown in English
Midaspray image
Midaspray image

Product introduction

Midaspray is taken under the supervision of a healthcare professional only or used after the proper guidance of a doctor. Take this medicine in the dose and duration as advised by your doctor, as it has a high potential for habit-forming.


If you have missed a dose, take it as soon as you remember it and finish the full course of treatment, even if you feel better. This medication must not be stopped suddenly without talking to your doctor, as it may cause nausea and anxiety.


Side effects of this medicine include sleepiness, headache, nasal discomfort, throat irritation, and rhinorrhea (runny nose). Do not drive or do anything that requires mental focus until you know how this medicine affects you. These side effects are usually short-lasting and resolve on their own. Consult your doctor if they bother you or do not go away. Inform your doctor if you are pregnant, planning to conceive, or breastfeeding, before taking this medicine.

Uses of Midaspray Nasal Spray

  • Seizures

Benefits of Midaspray Nasal Spray

Seizures
Seizures occur due to sudden, uncontrolled electrical disturbances in the brain, leading to jerking movements, confusion, or loss of awareness. Midaspray helps quickly control these episodes, reducing their duration and severity. Its fast onset makes it particularly useful in emergency settings, helping prevent complications and supporting rapid stabilization.

Side effects of Midaspray Nasal Spray

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Midaspray
  • Vomiting
  • Throat irritation
  • Runny nose
  • Injection site pain
  • Sleepiness
  • Apnea (absence of breathing)
  • Decreased respiratory rate
  • Nasal discomfort

How to use Midaspray Nasal Spray

Use this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Insert the bottle tip into one nostril and close the other nostril. Direct the spray towards the sides of your nostril, away from the cartilage dividing the two sides of your nose. As you spray, breath gently and keep the head upright. Repeat the same process for the other nostrils.

How Midaspray Nasal Spray works

Midaspray is a benzodiazepine (BZD). It is rapidly absorbed into the bloodstream through the inner lining of the nose. Once absorbed, it works by increasing the action of GABA, a chemical messenger that suppresses the abnormal and excessive activity of the nerve cells in the brain. This helps the patient to recover from a seizure faster.

Quick tips

  • The addiction / habit-forming potential of this medicine is very high. Take it only as per the dose and duration advised by your doctor
  • It may cause dizziness. Do not drive or do anything that requires mental focus until you know how this medicine affects you.
  • Avoid consuming alcohol as it may increase dizziness and drowsiness.
  • Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
  • Do not stop taking medication suddenly without talking to your doctor as that may lead to nausea, anxiety, agitation, flu-like symptoms, sweating, tremor, and confusion.
  • The addiction / habit-forming potential of this medicine is very high. Take it only as per the dose and duration advised by your doctor
  • It may cause dizziness. Do not drive or do anything that requires mental focus until you know how this medicine affects you.
  • Avoid consuming alcohol as it may increase dizziness and drowsiness.
  • Inform your doctor if you are pregnant, planning to conceive or breastfeeding.

Safety advice

Alcohol

Alcohol

No interaction found/established
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Midaspray is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Midaspray may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Midaspray should be used for short periods and sleepiness of the baby should be watched. The withdrawal of Midaspray should be gradual.
Driving

Driving

No interaction found/established
Kidney

Kidney

No interaction found/established
Liver

Liver

No interaction found/established

Interaction with drugs

Taking Midaspray with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Tramadol (Injection Route)

If concurrent use is essential, watch out for symptoms of Midazolam side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Midazolam as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.
Severe

Clozapine (Oral Route)

If concurrent use is essential, watch out for symptoms such as dizziness, headaches, tremors, sleep disturbances or mood changes and consult your doctor if you experience them. They may adjust the doses as per the observations.
Severe

Tramadol (Oral Route)

If concurrent use is essential, watch out for symptoms of Midazolam side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Midazolam as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.
Severe

Morphine (Oral Route)

If concurrent use is essential, watch out for symptoms of Midazolam side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Midazolam as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.
Severe

Codeine (Oral Route)

If concurrent use is essential, watch out for symptoms of Midazolam side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Midazolam as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.

Frequently asked questions

Midaspray is safe if used at prescribed doses for the prescribed duration as advised by your doctor
Yes, Midaspray is a controlled substance
Yes, Midaspray a sedative medication used before and during diagnostic or surgical procedures either in combination with or without local anesthesia
No, Midaspray is not an opiate medication
Yes, Midaspray belongs to benzodiazepine class of sedative medication
No, Midaspray belongs to schedule 4. It has low potential for abuse
Versed is a brand (trade) name for Midaspray
No, Midaspray does not have any analgesic properties. It is used as a central nervous system depressant that slows brain activity, causes relaxation and induces sleep (anesthetic)
No, Midaspray does not make you high; it makes you sleepy as it is a central nervous system depressant that slows brain activity, causes relaxation and induces sleep
Yes, Midaspray causes retrograde amnesia (short term loss of memory)
No, Midaspray does not hasten death. Although it may be used to induce sleep and relive anxiety in terminally-ill patients not responding to other relevant medications
Yes, Midaspray crosses the placenta.

Fact Box

Chemical Class

Imidazo [1,5- a] [1,4] benzodiazepines

Habit Forming

Yes

Therapeutic Class

NEURO CNS

Action Class

Benzodiazepines

References

  1. Stahl SM, editor. Midazolam. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 431-33.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 914-15.
  3. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 20 Mar. 2019] (online) Available from:
  4. Midazolam. Smyrna, GA: UCB, Inc.; 2023. [Accessed 23 Apr 2026] (online).
  5. Midazolam. Smyrna, GA: UCB, Inc.; 2023. [Accessed 23 Apr 2026] (online).
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User feedback

Once A Day
88%
Twice A Day
7%
Once A Month
2%
Four Times A Day
2%
Others
100%
Average
100%
Vomiting
33%
Headache
33%
Sleepiness
33%
With or without food
100%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Vendor Details

Country of origin: India

Lab tests offered by us

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