Midarine 100mg Injection

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Midarine 100mg Injection belongs to a group of medicines called muscle relaxants. It is used along with general anesthesia or sedatives to provide skeletal muscle relaxation during surgical procedures. It is also used to facilitate emergency airway management in patients in intensive care.

Midarine 100mg Injection is administered by a healthcare professional. You should not self-administer this medicine at home. The dose and duration will depend on what you are taking it for and how well it helps your symptoms.

The most common side effects of this medicine include stomach pressure, excessive salivation, muscle twitching, and postoperative muscle pain. Other common side effects include increased intraocular pressure, slow heart rate, increased heart rate, flushing of the skin, high blood pressure, low blood pressure, rash, and increased potassium level in blood. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.

Before using it, to make sure it is safe for you, you should let your doctor know if you have any other medical conditions or disorders. You should also tell your doctor all the other medicines you are using or taking. Pregnant and breastfeeding women should consult their doctors before using this medicine.

Uses of Midarine Injection

  • Skeletal muscle relaxation during surgery

Benefits of Midarine Injection

In Skeletal muscle relaxation during surgery

Midarine 100mg Injection is used to relax muscles during anesthesia and surgical procedures. It works by blocking chemical messengers in the brain that are responsible for rigidity, inflammation, or swelling. It effectively relieves muscle stiffness or spasm, thereby improving muscle movement.
It is given as an injection by a doctor or nurse and should not be self-administered. The dose and duration will be decided by the doctor depending on the condition you are being treated for. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Side effects of Midarine Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Midarine

  • Stomach pressure
  • Excessive salivation
  • Muscle twitching
  • Postoperative muscle pain
  • Increased intraocular pressure
  • Slow heart rate
  • Increased heart rate
  • Flushing of skin
  • High blood pressure
  • Hypotension (low blood pressure)
  • Rash
  • Increased potassium level in blood

How to use Midarine Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Midarine Injection works

Midarine 100mg Injection relaxes the muscles by blocking the impulses from the nerves.

Safety advice

It is not known whether it is safe to consume alcohol with Midarine 100mg Injection. Please consult your doctor.
Midarine 100mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
Midarine 100mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Not relevant, as Midarine 100mg Injection is intended for use in hospitalised patients.
Midarine 100mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Midarine 100mg Injection may be needed. Please consult your doctor.
Midarine 100mg Injection should be used with caution in patients with liver disease. Dose adjustment of Midarine 100mg Injection may be needed. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Midarine 100mg Injection
Myorelex 100mg Injection
Neon Laboratories Ltd
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Suxalin 100mg Injection
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Quick tips

  • Midarine 100mg Injection is given as an injection into vein under the supervision of a doctor.
  • It makes you feel dizzy or drowsy. Do not drive until you know how Midarine 100mg Injection affects you.
  • Your doctor will monitor your blood pressure regularly as the medicine may lead to high blood pressure.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Fact Box

Chemical Class
Acyl Cholines Derivative
Habit Forming
Therapeutic Class
Action Class
Skeletal muscle relaxant- Peripherally acting

Patient concerns

Pain in right arm and calf muscle after recovering during bypass surgery Anyone here Please help me
Dr. Nabajit Talukdar
When was cabg done
Road accident. Now cured. Is physiotherapy mandatory after removal of POP?? Sir, I met with road accident exactly 63 days ago. Now POP is removed. Still can't walk without walking aid. Doctor told physiotherapy is not required. And not suggested any exercises also for muscle relaxation. Sir, please suggest me , whether I should consult another doctor or exercises not always mandatory
Dr. Akshat Goel
Physiotherapy is not mandatory Home exercises are needed for all cases


Q. Why does Midarine 100mg Injection cause bradycardia (abnormally slow heart beat)?

The initial metabolite of Midarine 100mg Injection produces a transient negative chronotropic effect through its stimulation of sinus node muscarinic receptors. Repeated dosing or infusions of Midarine 100mg Injection may lead to bradycardia that is appropriately treated with atropine

Q. Why does Midarine 100mg Injection cause fasciculation (twitching of muscles under the skin)?

Midarine 100mg Injection cause fasciculation by an action on some distal part of motor nerve fibres

Q. Is Midarine 100mg Injection still used?

Midarine 100mg Injection is still used during general anesthesia

Q. Is Midarine 100mg Injection reversible?

Midarine 100mg Injection is a short-acting muscle relaxant which exerts a depolarizing effect at the neuromuscular junction. This effect is not reversible pharmacologically

Q. Is Midarine 100mg Injection is contraindicated in burned patients?

Yes, Midarine 100mg Injection should not be used in burned patients

Q. Does Midarine 100mg Injection cross the placenta?

In normal therapeutic doses, Midarine 100mg Injection does not cross the placental barrier in sufficient amounts.

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  1. Suxamethonium. Co Dublin, Ireland: Mercury Pharma International Ltd.; 1990 [revised Jul. 2018]. [Accessed 02 Apr. 2019] (online) Available from:External Link
  2. Suxamethonium. Business Campus, Dublin: Aspen Pharma Trading Limited; 30 Aug. 1985 [revised 1 Aug. 2017]. [Accessed 02 Apr. 2019] (online) Available from:External Link

Manufacturer/Marketer address

Dr. Annie Besant Road, Mumbai - 400 030
Expires on or after: December, 2021

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