Mesacol 500mg Suppository
Product introduction
Mesacol 500mg Suppository is a medicine used to treat Crohn’s disease and ulcerative colitis. It is used when the lining tissue of the inner rectum becomes inflamed (proctitis). It helps to reduce symptoms such as diarrhea, bleeding, and stomach pain by reducing inflammation in the bowel.
Mesacol 500mg Suppository is only for the rectal route and should not be taken orally. It must be used under the supervision of a doctor or healthcare professional. Stay in a lying position for at least 15 minutes after the insertion of suppositories. The dose will depend on what you are being treated for, but take it exactly as your doctor prescribes. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early, your symptoms may come back, and your condition may worsen.
The most common side effects of this medicine include rectal discomfort, rash, itching, and fever. If these symptoms bother you or do not go away or get worse, tell your doctor. There may be ways of reducing or preventing them.
Before taking it, tell your doctor if you have any kidney or liver problems or a blockage in your stomach. Your age may also be a factor in deciding whether this medicine is suitable. Pregnant or breastfeeding women should also consult their doctor before taking this medicine. Let your doctor know about all other medications you are taking, as some may affect or be affected by this medicine. You may be asked for kidney and liver function tests before and after the treatment.
Uses of Mesacol Suppository
Benefits of Mesacol Suppository
In Treatment of Ulcerative colitis
Mesacol 500mg Suppository works directly on the inflamed areas of the colon and rectum to reduce swelling and irritation. This helps relieve symptoms like abdominal pain, bleeding, and frequent bowel movements associated with ulcerative colitis. It also helps prevent future flare-ups and keeps the condition under control.
In Treatment of Crohn’s disease
In patients with Crohn's disease, Mesacol 500mg Suppository helps reduce inflammation in the digestive tract, easing symptoms like stomach pain, diarrhea, and fatigue. It can help control flare-ups and maintain remission, preventing symptoms from returning.
Side effects of Mesacol Suppository
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Mesacol
- Rectal discomfort
- Abdominal pain
- Flatulence
- Headache
- Diarrhea
- Nausea
- Vomiting
- Rash
How to use Mesacol Suppository
Remove the wrapper from the suppository before inserting it. Keep lying down for about 15 minutes after insertion so that the suppository does not come out before it melts.
How Mesacol Suppository works
Mesacol 500mg Suppository is an aminosalicylate. It works directly on the site of inflammation (swelling) in the lower parts of the large intestine (colon and rectum) to provide rapid relief from attacks of ulcerative colitis. It suppresses the production of chemical messengers (prostaglandins) that cause intestinal inflammation, thereby reducing ulceration, bleeding, and painful symptoms.
Safety advice
Alcohol
No interaction found/established
Pregnancy
CONSULT YOUR DOCTOR
Mesacol 500mg Suppository may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Mesacol 500mg Suppository is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
If you are taking Mesacol 500mg Suppository, monitor the baby for diarrhea.
If you are taking Mesacol 500mg Suppository, monitor the baby for diarrhea.
Driving
No interaction found/established
Kidney
CAUTION
Mesacol 500mg Suppository should be used with caution in patients with kidney disease. Dose adjustment of Mesacol 500mg Suppository may be needed. Please consult your doctor.
Use of Mesacol 500mg Suppository is not recommended in patients with severe kidney disease.
Use of Mesacol 500mg Suppository is not recommended in patients with severe kidney disease.
Liver
CAUTION
Mesacol 500mg Suppository should be used with caution in patients with liver disease. Dose adjustment of Mesacol 500mg Suppository may be needed. Please consult your doctor.
What if you forget to take Mesacol Suppository?
If you miss a dose of Mesacol 500mg Suppository, use it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Mesacol 500mg Suppository
₹19.57/Suppository
Meslataj Suppository
Taj Pharma India Ltd
₹16.48/suppository
16% cheaper
Quick tips
- Mesacol 500mg Suppository is for administration into the back passage (rectum). It must not be taken by mouth.
- Avoid taking antacids with Mesacol 500mg Suppository as it can make your inflammation worse.
Fact Box
Chemical Class
Aminosalicylic Acids Derivative
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
5-Aminosalicylic Acid (5-ASA)
Interaction with drugs
Taking Mesacol with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
If concurrent use is essential, your doctor may monitor blood cell counts and your overall treatment closely.
Concurrent use may increase the risk of harmful effects on the blood,
If concurrent use is essential, your doctor may monitor blood cell counts and your overall treatment closely.
Concurrent use may increase the risk of low blood cell counts.
If concurrent use can not be avoided, your doctor may monitor your blood cell counts.
Concurrent use may increase the risk of fall in white blood cell count.
Your doctor may monitor your blood cell count and adjust the doses as per the observations.
Concurrent use may increase the risk of low blood cell counts.
Patient concerns
FAQs
My symptoms have improved can I stop using Mesacol 500mg Suppository?
Continue to use Mesacol 500mg Suppository as advised by the doctor, even if you feel better at the beginning of your treatment. Do not stop using Mesacol 500mg Suppository without consulting your doctor.
I am suffering from ulcerative colitis (UC) and piles can I use Mesacol 500mg Suppository?
Mesacol 500mg Suppository is used for the treatment of ulcerative colitis; however, you should not start using the medicine on your own. Consult a doctor who will prescribe you the right dose and duration of treatment and will address any related or other concerns that you have.
Can I drink alcohol while using Mesacol 500mg Suppository?
You should avoid alcohol if you have ulcerative colitis, as alcohol will irritate your stomach and intestines, which will worsen your condition. Although alcohol does not interfere with the working of Mesacol 500mg Suppository, you should consult your doctor before using alcohol.
What is the best time to use Mesacol 500mg Suppository?
Use Mesacol 500mg Suppository exactly as directed by your doctor. If you are using Mesacol 500mg Suppository suppositories, you should insert them rectally, once daily at bedtime.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 867-69.
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Mesalamine. [Updated 2019 Apr 1]. [Accessed 20 Feb. 2020] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:
- Mesalazine [Product Information]. Pymble, NSW: Ferring Pharmaceuticals Pty Ltd.; 2023. [Accessed 11 Jul. 2023]. (online) Available from:
- Mesalazine [New Zealand Data Sheet]. Mt Wellington, Auckland: Pharmaco (NZ) Ltd.; 2023. [Accessed 11 Jul. 2023]. (online) Available from:
Marketer details
Name: Sun Pharmaceutical Industries Ltd
Address: Plot no 107/108,Namli block , Ranipool, East Sikkim 737135
Country of origin: India
Expires on or after: February, 2026
A licensed vendor partner from your nearest location will deliver Mesacol 500mg Suppository. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: February, 2026
A licensed vendor partner from your nearest location will deliver Mesacol 500mg Suppository. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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