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Melitra 10 Tablet

Written By Dr. Swati Mishra, BDS
Reviewed By Dr. Mekhala Chandra, MD, MBBS
Last updated on 05 Dec 2025 | 05:48 PM (IST)
Melitra 10 Tablet is an antidepressant. It is used to treat depression and anxiety. It helps to improve and brighten up the mood. It is also effective in treating depression that is unresponsive to other treatments.
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General Information

The content is shown in English
Melitra 10 Tablet image
Melitra 10 Tablet image
Melitra 10 Tablet image
Melitra 10 Tablet image
Melitra 10 Tablet image
Melitra 10 Tablet image
Melitra 10 Tablet image

Product introduction

Melitra 10 Tablet is best taken before bedtime because it can make you feel drowsy. It can be taken with or without food. Take it at a fixed time each day for best results. The dose and duration will be decided by your doctor so that you get the right amount to control your symptoms. This medication must not be stopped suddenly without talking to the doctor. Your dose may be modified or gradually decreased before completely stopping the medication.


The most common side effects of this medicine include increased heart rate, blurred vision, dryness in the mouth, difficulty in urination, and constipation. Initially, this medicine may also cause a sudden drop in blood pressure, especially when you change positions. It may even cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. To lower the chances of dizziness, rise slowly if you have been sitting or lying down. It may also lead to weight gain in some people. Most of the common side effects tend to be mild and temporary. Your doctor may be able to suggest ways of preventing or reducing side effects if they bother you or do not go away. Serious side effects with this medicine are rare.


Before taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same or any other diseases. Pregnant and breastfeeding women should take this medicine with proper consultation and caution. This medicine is not known to be addictive, but you can experience additional side effects (withdrawal symptoms) if you stop taking it suddenly. If you notice any sudden mood change or suicidal or self-harm thoughts, you must consult the doctor without delay. Also, remember to take this medicine strictly as advised by the doctor, as an overdose of this medicine may lead to a serious health emergency. Consumption of alcohol should be avoided as alcohol interacts with this medicine to cause serious health issues.

Benefits of Melitra Tablet

Treatment of Depression
Depression is a condition marked by persistent sadness, loss of interest, and low energy, which can affect daily life. Melitra 10 Tablet helps improve mood, restore emotional balance, and reduce feelings of hopelessness, supporting better mental well-being.
Treatment of Anxiety
Anxiety involves excessive worry, restlessness, and tension that can interfere with daily activities. Melitra 10 Tablet helps calm the mind, reduce nervousness, and improve overall emotional stability, making it easier to manage stress and daily challenges.

Side effects of Melitra Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Melitra
  • Blurred vision
  • Difficulty in urination
  • Dryness in mouth
  • Weight gain
  • Constipation
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Increased heart rate

How to use Melitra Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Melitra 10 Tablet may be taken with or without food.

How Melitra Tablet works

Melitra 10 Tablet is a tricyclic antidepressant. It increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.

Quick tips

  • It may take 4 to 6 weeks for Melitra 10 Tablet to start working. Keep taking it as prescribed.
  • It may cause sleepiness. Take it at bedtime and do not drive or do anything requiring concentration until you know how it affects you.
  • Avoid consuming alcohol when taking Melitra 10 Tablet, as it may cause excessive sleepiness.
  • Monitor your weight during the treatment as this medicine can cause weight gain and increased appetite.
  • It may cause a sudden drop in your blood pressure. Rise slowly if you have been sitting or lying down.
  • Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.

Safety advice

Alcohol

Alcohol

UNSAFE
Do not drink alcohol while you are taking this medicine. Melitra 10 Tablet may cause excessive drowsiness when taken with alcohol.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Information regarding the use of Melitra 10 Tablet during pregnancy is not available. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Melitra 10 Tablet during breastfeeding is not available. Please consult your doctor.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Melitra 10 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Melitra 10 Tablet in patients with kidney disease. Please consult your doctor.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Melitra 10 Tablet in patients with liver disease.

Interaction with drugs

Taking Melitra with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Procarbazine (Oral Route)

Avoid concurrent use. Please consult with your doctor.
Moderate

Lithium carbonate (Oral Route)

Careful consideration is advised when taking Lithium carbonate with Melitracen. If concurrent use is essential, watch out for symptoms such as impaired movements, dizziness or drowsiness and consult your doctor if you experience them.
Moderate

Levodopa (Oral Route)

Monitor your blood pressure and inform your doctor if you notice severe high blood pressure.

Frequently asked questions

Melitra 10 Tablet is used to treat depression and anxiety that is unresponsive to any other alternative treatment. It restores the chemical imbalance in the brain and enhances mood and behavior.
No, you must not stop taking Melitra 10 Tablet suddenly, even if you are feeling better, as it may worsen your condition. Continue taking Melitra 10 Tablet for the duration prescribed by your doctor to get maximum benefit. If any of the side effects bother you, consult your doctor. In case you have completed your course of treatment, your doctor will reduce your dose gradually before taking you off this medicine completely.
Melitra 10 Tablet may cause drowsiness and dizziness, especially at the beginning of the treatment. Do not drive or work with tools or machinery if your alertness is affected. It is not advisable to drink alcohol during treatment with this medicine, as it might worsen the drowsiness. Inform your doctor if you have any problems with your liver or kidneys. Let your doctor know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Inform your doctor if you are pregnant, planning to conceive, or breastfeeding to prevent any harmful effects on the baby.
Yes, Melitra 10 Tablet can cause urinary problems. It is more commonly seen in elderly patients who are above 65 years of age. The patient may face difficulty in passing urine, which can further lead to a urinary tract infection. You should consult your doctor immediately if you develop these symptoms.

Fact Box

Chemical Class

Anthracenes

Habit Forming

No

Therapeutic Class

NEURO CNS

Action Class

Tricyclic Antidepressants (TCAs)

References

  1. Bexinfo: Therapeutic Guide. Dhaka, Bangladesh: Beximco Pharmaceuticals Ltd.; 2013. pp. 246-47.
  2. Zeelab Pharmacy: Melitracen [Product Information]. [Accessed 05 Dec. 2025] (online) Available from:
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User feedback

Once A Day
85%
Twice A Day
15%
Depression
40%
Others
40%
Anxiety
20%
Excellent
67%
Average
33%
Difficulty in urination
100%
With food
100%
Expensive
67%
Average
33%
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Obsurge Biotech Ltd
Address: 101-102 Aditya Tower, District Centre, Laxmi Nagar, Delhi : 110092, India

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Country of origin: India
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