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Last updated:
18 Feb 2020 | 05:25 PM (IST)
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Megval 50mg Injection

Prescription Required
SALT COMPOSITION

Overview

Introduction

Megval 50mg Injection is used to treat cancer of ovaries and a type of cancer of bone marrow called multiple myeloma. It may be also used to treat other conditions, as determined by the doctor.

Megval 50mg Injection is given as an injection into veins by the doctor, but try to take it at the same time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. It makes skin more sensitive towards sunlight, wear protective clothing or use sunscreen.

The most common side effects of this medicine include nausea, vomiting, anemia (low number of red blood cells) and hair loss. This medicine may reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidney, liver and heart function during treatment with this medicine. Inform your doctor if you observe signs of infections such as fever, chills, body ache or if you have unusual bruising or bleeding and  bleeding gums or blood in your urine or stool.

Before taking it, tell your doctor if you have bleeding, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Megval Injection

Side effects of Megval Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Megval

  • Nausea
  • Vomiting
  • Stomatitis (Inflammation of the mouth)
  • Anemia (low number of red blood cells)
  • Hair loss
  • Low blood platelets
  • Diarrhea
  • Decreased white blood cell count

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Nausea
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop from feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Vomiting
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Anemia (low number of red blood cells)
    Making some simple lifestyle changes can raise your red blood cell count. Reduce the amount of alcohol you drink, eat a well-balanced healthy diet and take regular exercise. Physical activities make your body need more oxygen and this stimulates the production of red blood cells. There are some vitamins which are important such as vitamin B-12, vitamin B-9, vitamin C and Vitamin A. Also, some minerals such as iron (especially) and copper. Aim for foods which contain higher quantities of these vitamins and minerals or ask your doctor for supplements. Make sure to consult your doctor for complete evaluation and treatment of anemia.
  • Coping with Hair loss
    Use gentle hair products such as baby shampoo. Use a soft brush and comb gently. Avoid using hairdryers, curling tongs or hair straighteners and pat your hair dry after washing. Do not color your hair. Protect your scalp by covering your head in the sun. It is necessary to not take the stress and eat a balanced, nutritious diet as it is vital for the health of your hair.
  • Coping with Low blood platelets
    You will need a blood test to find out if your blood platelet level is low. If this medicine is causing your platelet levels to drop, your doctor may suggest an alternative medicine. There are also medicines that can boost your blood platelet level. Consider asking your doctor about this. A low platelet count can put you at risk for bleeding. Try to be careful when doing activities that might cause an injury or a cut as it may take longer to stop bleeding.
  • Coping with Diarrhea
    Keep up your intake of fluids and electrolytes (sugars and salts) to avoid getting dehydrated. Eat less fiber (avoid raw fruits, fruit juice and vegetables). Talk to your doctor about possible medication to manage diarrhea. Ask about reducing the dosage of your drug or other suitable treatments.
  • Coping with Decreased white blood cell count
    If you have a low level of white blood cells, you are more likely to get infections. There are several ways to reduce your chances of catching or spreading an infection. Avoid unnecessary exposure to germs when you can. Wash your hands frequently and thoroughly with soap or use a sanitiser. Avoid crowds and avoid contact with people who are ill or have infections. Use disposable tissues for coughs and sneezes. Consider using an appropriate face mask. Do not share personal items like cutlery, glasses, towels or toothbrushes with others. Get enough rest and eat a well balanced healthy diet.

How to use Megval Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Megval Injection works

Megval 50mg Injection is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.

Safety Advice

Alcohol
CAUTION
Caution is advised when consuming alcohol with Megval 50mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Megval 50mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breastfeeding
UNSAFE
Megval 50mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Megval 50mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CAUTION
Megval 50mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Megval 50mg Injection may be needed. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Megval 50mg Injection in patients with liver disease. Please consult your doctor.

What if you forget to take Megval Injection?

If you miss a dose of Megval 50mg Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
No alternate brands found for this medicine

Quick Tips

  • Megval 50mg Injection should be taken as per dose and duration suggested by the doctor.

Fact Box

Chemical Class
Nitrogen Mustard Compounds
Habit Forming
No

Patient Concerns

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Please tell me the interpretation of the attach report, if possible. Also guide for further treatment process.
Dr. Sanjay Singh Rai
Medical Oncology and Hematology
U r having multiple myeloma
Multiple myeloma can be cured or not
Dr. Rohan Khandelwal
Surgical Oncology
Yes, if diagnosed at the right stage
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Do you have any questions related to Megval 50mg Injection ?

FAQs

Q. Is Megval a vesicant (irritant)?

Megval is not a vesicant but an anti-cancer drug

Q. How is Megval given?

Megval is given by oral or intravenous route; dosing varies by purpose and route of administration as well as patient weight

Q. Does Megval cause hair loss/ neuropathy/ liver damage?

Megval causes hair loss as one of the side effects. but cause for liver damage and neuropathy is not known

Q. How does Megval work/ how does Megval kill cancer cells?

Megval belongs to class of drugs called alkylating agents. It works by stopping or slowing the growth of cancer cells in your body.

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Disclaimer:

1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1684.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 860-61.
  3. Drugs.com. Melphalan Pregnancy and Breastfeeding Warnings. [Accessed 26 Mar. 2019] (online) Available from:External Link
  4. Mephalan. Dublin, Ireland: Aspen; 2004 [revised Aug. 2014]. [Accessed 26 Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

255/2, Hinjawadi, Pune - 411057, India
A licensed vendor partner from your nearest location will deliver Megval 50mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
MRP2199  Get 15% OFF
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₹1869.15
1 Injection in 1 vial
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