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Mefran Spas Tablet is a prescription medicine that helps to provide symptomatic relief from menstrual (period-related) pain and cramps. It is also used to treat abdominal pain by relieving spasms of the muscles in the stomach and intestines.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 10 Apr 2026 | 12:12 AM (IST)
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Mefran Spas Tablet image
Mefran Spas Tablet image

Product introduction

Mefran Spas Tablet should be taken with food. This will prevent you from getting an upset stomach. The dose and duration will depend on what you are using it for and how well it helps your symptoms. Use it regularly and do not discontinue it unless the doctor tells you.


Common side effects of Mefran Spas Tablet include dizziness, dry mouth, blurred vision, nausea, diarrhea, headache, and sleepiness. If you experience any of these side effects and they do not go away or become worse, inform your doctor. Your doctor may be able to suggest ways to prevent or reduce these side effects. In general, you should try to use the smallest dose necessary to control your symptoms.


Before using Mefran Spas Tablet, you should tell your doctor if you have any kidney or liver problems or if you are taking any other medicines. Pregnant and breastfeeding women should also consult their doctors before using the medicine.

Uses of Mefran Spas Tablet

  • Treatment of Menstrual pain
  • Treatment of Abdominal cramp : Mefran Spas Tablet helps relieve painful muscle cramps in the abdomen caused by digestive problems, infections, or menstrual periods.

Benefits of Mefran Spas Tablet

Treatment of Menstrual pain
Menstrual pain occurs due to uterine contractions and inflammation during periods. Mefran Spas Tablet works by relaxing the uterine muscles and reducing pain-causing chemical messengers in the body. This helps relieve cramps, pain, bloating, and discomfort during menstruation, making periods more manageable.
Treatment of Abdominal cramp
Abdominal cramps can occur due to muscle spasms in the stomach and intestines. Mefran Spas Tablet relaxes smooth muscles and reduces pain and inflammation. This helps relieve cramping, discomfort, and spasms. It improves comfort and supports better daily functioning.

Side effects of Mefran Spas Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Mefran Spas
  • Constipation
  • Dyspepsia
  • Drowsiness
  • Itching
  • Ringing in ear
  • Breathlessness
  • Nausea
  • Dryness in mouth
  • Dizziness
  • Headache
  • Diarrhea

How to use Mefran Spas Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Mefran Spas Tablet should be taken with or after food.

How Mefran Spas Tablet works

Mefran Spas Tablet is a combination of two medicines: Dicyclomine and Mefenamic Acid. Dicyclomine is an anticholinergic that works by relaxing the muscles in the stomach and intestines. It stops sudden muscle contractions (spasms), thereby relieving cramps, pain, bloating, and discomfort. Mefenamic Acid is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that cause pain and inflammation. Together, these medicines help relieve menstrual cramps and stomach cramps.

Quick tips

  • Mefran Spas Tablet is used to relieve abdominal cramps and menstrual pain.
  • Take Mefran Spas Tablet with food to reduce stomach irritation.
  • Mefran Spas Tablet may cause dizziness, drowsiness, blurred vision, or difficulty concentrating. Do not drive or operate machinery until you know how it affects you.
  • Avoid alcohol while taking Mefran Spas Tablet, as it may increase drowsiness and stomach-related side effects.
  • Do not combine Mefran Spas Tablet with other NSAID painkillers unless advised by your doctor.
  • Dry mouth may occur; frequent mouth rinsing, hydration, or sugar-free gum may help.
  • This medicine may cause either constipation or diarrhea in some people. Consult your doctor if symptoms become severe or persistent.
  • Drink enough fluids, especially if you have cramps or diarrhea.
  • Stop taking Mefran Spas Tablet and seek urgent medical help if you notice black stools, vomit blood, or have severe stomach pain.
  • Seek medical advice if abdominal pain is severe, persistent, or associated with fever, vomiting, or blood in stools.
  • Inform your doctor if you have glaucoma, urinary retention, enlarged prostate, or bowel obstruction before taking Mefran Spas Tablet.
  • Stop using Mefran Spas Tablet and seek medical help if allergic reactions such as rash, swelling, or breathing difficulty occur.
  • Use Mefran Spas Tablet only for the duration advised by your doctor. Do not use it for long periods without medical advice.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Mefran Spas Tablet.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Mefran Spas Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

UNSAFE
Mefran Spas Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

UNSAFE
Mefran Spas Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

UNSAFE
Mefran Spas Tablet is unsafe to use in patients with kidney disease and should be avoided.
Liver

Liver

CAUTION
Mefran Spas Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Frequently asked questions

Yes, you should take Mefran Spas Tablet with food or immediately after food. This will prevent the occurrence of stomach upset, which is very common with this medicine. It is also advisable not to lie down immediately after taking the medicine.
No, Mefran Spas Tablet does not have any effect on menstrual bleeding, neither does it affect the amount nor the duration of bleeding. It does not affect the menstrual cycle and helps relieve the pain caused due to menstrual cramps.
Mefran Spas Tablet is not prescribed to be taken on a regular basis. Therefore, it is advised to take Mefran Spas Tablet for the shortest possible time advised by the doctor or only when you experience menstrual pain.
Yes, you should try to avoid driving after taking Mefran Spas Tablet as this medicine may cause dizziness or sleepiness. These side effects get worse with the consumption of alcohol. Hence, better to avoid driving or any attention-seeking activity until you know how the medicine affects you.

Fact Box

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS
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User feedback

Abdominal pain
57%
Menstrual pain
43%
Average
56%
Excellent
22%
Poor
22%
Sleepiness
50%
Blurred vision
25%
Weakness
25%
With food
100%
Not Expensive
67%
Average
33%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Mankind Pharma Ltd
Address: 208, Okhla Industrial Estate, Phase III, New Delhi - 110020

Vendor Details

Country of origin: India
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