Mazetol SR 300 Tablet

Prescription Required

Overview

Introduction of Mazetol Tablet ER

Mazetol SR 300 Tablet is a medicine used to treat epilepsy. It helps prevent and control seizures (fits). It can also be taken for nerve pain caused by diabetes (neuropathy) or a painful condition of the face called trigeminal neuralgia. Occasionally it is used to treat bipolar disorder.

Mazetol SR 300 Tablet may be used alone or in combination with other medicines. The dose and how often you need to take it will be decided by your doctor so that you get the right amount to control your symptoms. It may be increased gradually. You can take this medicine with or without food but take it at the same time each day to get the most benefit. It usually takes a couple of weeks to work. It is important to take this medicine regularly and for as long as you are advised, even if you feel well. Missing doses may trigger seizures and, if you stop, your condition may get worse. It should never be stopped suddenly.

The most common side effects of this medicine include nausea, vomiting, feeling dizzy, tired or drowsy, and unsteadiness. Most of these are not serious. Keep taking the medicine but talk to your doctor if these side effects bother you or do not go away. However, if you notice a skin rash or redness, tell your doctor straight away. It could develop into a life-threatening skin condition called Stevens-Johnson syndrome. Long-term treatment with this medicine can cause osteoporosis (reduced bone mass) and increase your risk of breaking a bone. Anticonvulsants like this medicine may cause suicidal thoughts and behaviors. If your mood becomes depressed, tell your doctor.

This medicine may not be suitable for everybody. Before using it, tell your doctor if you have ever had heart problems, kidney or liver disease, difficulty urinating, depression or suicidal thoughts. Many other medicines can interfere with it and some should not be taken together so tell your doctor all the medicines you are taking to make sure it is safe. If you are pregnant, do not start or stop taking this medicine without asking your doctor. Drinking alcohol should be avoided as it can increase some of the side effects and can also increase your risk of seizures. You may need frequent blood tests to help your doctor make sure you are taking the right dose both before you start and while you are using it.

Uses of Mazetol Tablet ER

Mazetol Tablet ER side effects

Common
  • Nausea
  • Vomiting
  • Dizziness
  • Balance disorder (loss of balance)
  • Drowsiness

How to use Mazetol Tablet ER

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Mazetol SR 300 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Mazetol Tablet ER works

Mazetol SR 300 Tablet is an antiepileptic medication. It controls seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain.

Mazetol Tablet ER related warnings

Alcohol
UNSAFE
Mazetol SR 300 Tablet may cause excessive drowsiness with alcohol
Pregnancy
CONSULT YOUR DOCTOR
Mazetol SR 300 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Lactation
SAFE IF PRESCRIBED
Mazetol SR 300 Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
Mazetol SR 300 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Mazetol SR 300 Tablet in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Mazetol SR 300 Tablet in patients with liver disease. Please consult your doctor.

What if you miss a dose of Mazetol Tablet ER?

If you miss a dose of Mazetol SR 300 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Mazetol SR 300 Tablet
₹2.9/Tablet ER
ZEN Retard 300 Tablet ER
Intas Pharmaceuticals Ltd
₹2.9/Tablet ER
same price
Tegrital CR 300 Divitabs
Novartis India Ltd
₹3.84/Tablet ER
32% costlier
Carbatol CR 300 Tablet
Torrent Pharmaceuticals Ltd
₹2.74/Tablet ER
save 6%

Expert Advice

  • Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
  • Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
  • Some healthy tips to prevent seizures:
    • Practice yoga every day.
    • Get enough sleep at nighttime.
    • Limit the use of screen time such as mobile/ laptop.
    • Take your medication on time.
  • It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
  • Your doctor may get regular tests done to monitor the level of blood cells in your blood while taking this medication. 
  • Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
  • Inform your doctor if you notice a rash or other skin changes such as reddish spot or circular patches while taking this medicine.
  • Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.

Interaction with Drugs

Taking Mazetol with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Itracip, Itraspan, Canzit
LIFE-THREATENING
Brand(s): Auxicasp, Canducid
SERIOUS
Brand(s): R Zep
SERIOUS
Brand(s): Norma, Cizonil
SERIOUS
Brand(s): Arthrox
SERIOUS
Brand(s): Ranisol, Vepred, Catapred
SERIOUS
Brand(s): Suclosz, Vizopin
SERIOUS
Brand(s): Leparox, Prx
SERIOUS
Brand(s): Stoin
SERIOUS

Patient Concerns

Questions Related to Mazetol

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I am suffering from trigeminal neuralgia since last 5 years. Taking zefratol 400 in the morning and half tablet at night along with Gabapen NT 400. I used to get good relief earlier but now I am getting frequent attacks while talking eating etc., Is there any permanent cure for thiis? Other than surgery?
Dr. Vikas Sharma
Neurologist
radio wave ablation may be helpful
I am a patient of epilepsy and i am using mazetol 200 tablet for last 6 years to avoid strokes.Is there any permanent treatement for this disease.
Dr. Vikas Sharma
Neurologist
No Medicine suppresses fits
arrow
Do you have any questions related to Mazetol SR 300 Tablet?

User Feedback


FAQs

Q. How quickly does Mazetol start working?

Your symptoms may take 1-2 weeks to improve. In some cases, it may take longer.

Q. Is Mazetol an analgesic? What is it used for?

No, Mazetol is not an analgesic and should not be used for regular aches or pains. It is an anti-epileptic medicine which is given to treat fits (seizures). It is also used to treat pain of trigeminal neuralgia and to control mood disorders when other medicines fail to work.

Q. What should I tell my doctor before taking this medicine?

Inform your doctor if you are taking any other medicines including medicines for epilepsy or seizures, medicines used to thin your blood (e.g., warfarin), birth control pills, medicines to control bacterial infection (e.g., chloramphenicol, metronidazole, and doxycycline), medicines to control viral infection (e.g., nelfinavir), and asthma medicines (e.g., theophylline and montelukast), etc. Also, inform your doctor if you are planning to become pregnant or are breastfeeding. Further, you should tell the doctor if you have ever had liver problems, kidney problems, lung problems, or porphyria (a rare blood pigment disorder).

Q. What are the long-term effects of Mazetol ?

The long-term side effects of Mazetol vary from person to person. While some people can take Mazetol safely for several years, some may develop side effects on using it for a long term. These side effects include osteoporosis and osteopenia in which the bones become weak and can be easily fractured. If you have been prescribed Mazetol for long term, get your bone density checked at regular intervals, maintain a healthy diet and exercise daily.

Q. What should I avoid while taking Mazetol?

If Mazetol makes you feel sleepy, avoid driving or operating heavy machinery. Alcohol consumption should be avoided since taking both together may cause excessive sleepiness.

Q. How do I stop taking Mazetol ?

You should stop Mazetol only after consulting your doctor. The dose of Mazetol should be reduced gradually so that the condition for which you are taking it does not recur.

Q. How can I look for early symptoms of suicidal thoughts and actions?

Pay attention to any changes, especially sudden changes in mood, behavior, thoughts, or feelings. Keep all follow-up visits with your doctor as scheduled. Call your doctor as needed, especially if you are worried about any symptoms.

Q. Can the use of Mazetol lead to weight gain? If yes, how can it be managed?

Yes, Mazetol commonly causes weight gain due to increase in appetite. You can manage your weight by eating a healthy diet, consuming low calorie food and including more vegetables and fruits in your diet. Regular physical exercise will be very helpful.

Q. Can the use of Mazetol affect my sex life?

Though rare but Mazetol may cause decreased sexual desire. It may also impair male fertility as it may reduce sperm count and/or motility. Consult your doctor if you develop these symptoms.

Q. I am taking Mazetol for trigeminal neuralgia. For how long do I need to take it?

Once the medicine relieves your pain, talk to your doctor who will gradually reduce your dose. After taking the reduced dose for several weeks, Mazetol can possibly be stopped if there is no recurrence of pain.

Q. How can I reduce the side effects of Mazetol?

Side effects of Mazetol can be reduced by starting it at a low dose and then increasing the dose gradually, until an effective dose is reached.

Q. When should I go for laboratory test when taking this drug?

Before starting treatment with Mazetol, your doctor may ask you to get regular blood tests, liver tests, and in some cases, even urine test. You may need to take these tests from time to time during your treatment. This is quite usual and nothing to worry about.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Stahl SM, editor. Carbamazepine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 105-110.
  2. McNamara JO. Pharmacotherapy of the Epilepsies. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 594-95.
  3. Porters RJ, Meldrum BS. Antiseizure Drugs. Sedative-Hypnotic Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 405-406.
  4. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 197-201.
  5. Carbamazepine. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2018. [Accessed 19 Jun. 2019] (online) Available from:External Link
  6. Carbamazepine. Hatfield, Hertfordshire: Generics UK T/A Mylan; 2009 [revised Sep. 2018]. [Accessed 24 Jan. 2019] (online) Available from:External Link
  7. Carbamazepine. Hoofddorp, The Netherlands: Sun Pharmaceutical Industries Europe B.V.; 2019. [Accessed 06 Feb. 2019] (online) Available from:External Link
  8. Carbamazepine. Potters Bar, UK: Generics [UK] Limited; 2016. [Accessed 19 Jun. 2019] (online) Available from:External Link
  9. Drugs.com. Carbamazepine Pregnancy and Breastfeeding Warnings. [Accessed 20 Mar. 2019] (online) Available from:External Link
  10. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 20 Mar. 2019] (online) Available from:External Link
  11. Central Drugs Standard Control Organisation (CDSCO). [Accessed 20 Mar. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India
A licensed pharmacy from your nearest location will deliver Mazetol SR 300 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.
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