Mannitol 20% Infusion

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 10 Apr 2026 | 10:57 AM (IST)

Mannitol 20% Infusion is a medicine used in the treatment of acute renal (kidney) failure, cerebral edema (accumulation of excessive fluid in the brain) and to reduce the pressure inside the eyes in a condition called glaucoma.

Genuine

Authenticity Assured

Prescription

required

NPPA Regulated

Show Details

₹79.2 MRP ₹87.7210% off

Save more with additional offers

Pay with Amazon Pay Balance and get cashback up to Rs. 100 with minimum cashback of Rs. 20

Earn cashback up to Rs. 100 with Amazon Pay Later

Assured cashback up to ₹300 on minimum payment of ₹300 using Paytm UPI*

Save more with additional offers

Pay with Amazon Pay Balance and get cashback up to Rs. 100 with minimum cashback of Rs. 20

Earn cashback up to Rs. 100 with Amazon Pay Later

Assured cashback up to ₹300 on minimum payment of ₹300 using Paytm UPI*

10% cashback up to 200 on Min Transaction of Rs.1000, for first time users of Airtel Payments Bank.

Get cashback up to ₹500

Get upto Rs.500 Cashback on minimum transaction of Rs.999/- with Mobikwik Wallet.

Get upto Rs.150 Cashback

General Information

Contains

Mannitol (20% w/v)

Marketer

Albert David Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Mannitol 20% Infusion works by removing excess water and also relieves inflammation in the affected areas. It may be used alone or in combination with other medicines. It is administered as an injection under the supervision of a medical professional and should not be self administered. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember.

Some common side effects of this medicine include nausea, vomiting, headache, and dehydration. You may also notice some injection site reactions such as pain, redness or swelling. However, these are temporary and usually subside on their own after some time. Please consult your doctor if these do not subside or bother you. Regular monitoring by blood tests may be required while using this medicine.

Uses of Mannitol Infusion

Glaucoma
Acute renal failure
Cerebral edema (accumulation of excessive fluid in the brain)

Benefits of Mannitol Infusion

Glaucoma
Mannitol 20% Infusion is used in glaucoma to rapidly lower eye pressure, providing relief from pain and helping prevent vision loss during acute episodes.

Acute renal failure
In acute renal failure, Mannitol 20% Infusion supports urine production and helps flush out toxins, aiding in kidney function recovery.

Cerebral edema (accumulation of excessive fluid in the brain)
Mannitol 20% Infusion helps reduce swelling in the brain by drawing excess fluid away, relieving pressure and lowering the risk of complications from brain injuries or conditions.

Side effects of Mannitol Infusion

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Mannitol

Nausea
Vomiting
Headache
Dehydration
Injection site reactions (pain, swelling, redness)

How to use Mannitol Infusion

Your doctor or nurse will give you this medicine. Kindly do not self-administer.

How Mannitol Infusion works

Mannitol 20% Infusion is an inert substance with high osmotic pressure. It draws water into the kidney, which in turn increases the amount of urine production. Mannitol 20% Infusion is also used to lower the pressure inside the eye or swelling around the brain.

All substitutes for Mannitol 20% Infusion

For information purposes only. Consult a doctor before taking any medicine.

Manitol 20% Infusion

by Otsuka Pharmaceutical India Pvt Ltd

₹0.22/ml of infusion

4% cheaper

Fabitol 20% Infusion

by Elkos Healthcare Pvt Ltd

₹0.25/ml of infusion

9% costlier

Quick tips

It is given as an injection into the veins by a doctor or healthcare professional.
Your doctor may get regular blood tests done to monitor sodium and potassium level, kidney function, and lung function while you are taking this medicine.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
It is given as an injection into the veins by a doctor or healthcare professional.
Your doctor may get regular blood tests done to monitor sodium and potassium level, kidney function, and lung function while you are taking this medicine.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Mannitol 20% Infusion. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Mannitol 20% Infusion during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Mannitol 20% Infusion during breastfeeding is not available. Please consult your doctor.

Driving

NOT RELEVANT

Not relevant, as Mannitol 20% Infusion is intended for use in hospitalized patients.

Kidney

CAUTION

Mannitol 20% Infusion should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Mannitol 20% Infusion should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Mannitol with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Tobramycin (Injection Route)

Do not consume Tobramycin with Mannitol. If concurrent use is essential, your doctor may monitor your kidney function closely.

Severe

Tobramycin (Inhalation Route)

Do not consume Tobramycin with Mannitol. If concurrent use is essential, your doctor may monitor your kidney function closely.

Severe

Tobramycin (Oral Route)

Do not consume Tobramycin with Mannitol. If concurrent use is essential, your doctor may monitor your kidney function closely.

Moderate

Lamivudine (Oral Route)

Do not consume Lamivudine with Mannitol. If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Mannitol may reduce blood levels of Lamivudine.

Moderate

Atracurium (Injection Route)

Talk to your doctor if you notice any unusual symptoms. Your doctor may adjust the dose if required. Mannitol may increase the effect of Atracurium.

Frequently asked questions

What is Mannitol 20% Infusion used for?

Mannitol 20% Infusion is used to help remove extra fluid from your body. It is often given in hospitals to reduce pressure in the brain (after injury or surgery) or in the eyes (like in glaucoma). It can also help your kidneys produce urine when they are not working well and help flush out certain poisons from the body.

Who should not receive Mannitol 20% Infusion?

Individuals should not receive Mannitol 20% Infusion if they have severe kidney problems, heart failure, lung congestion, severe dehydration, or active bleeding inside the brain (except during surgery). It should also be avoided if the individual is allergic to mannitol.

Is Mannitol 20% Infusion safe for people with kidney problems?

Mannitol 20% Infusion should be used with great care if your kidneys are not working well. Your doctor may give a small test dose first to check if your kidneys can handle it. If you stop passing urine or your kidney function worsens, the treatment is usually stopped immediately.

Can Mannitol 20% Infusion cause brain swelling or confusion?

In some people, Mannitol 20% Infusion can cross into the brain and cause confusion, drowsiness, or even worsen swelling in certain cases, especially if the protective barrier between the brain and blood is damaged. Your doctor will monitor you closely to avoid this.

What serious side effects of Mannitol 20% Infusion should I watch for?

Serious side effects of Mannitol 20% Infusion may include difficulty breathing, chest pain, confusion, reduced urination, or swelling in your feet. These can be signs of fluid overload, heart failure, or kidney problems, which require medical attention.

Why is Mannitol 20% Infusion used to lower pressure in the brain and eyes?

Mannitol 20% Infusion helps draw excess fluid out of tissues into the bloodstream, reducing swelling and pressure in the brain and eyes. It is commonly used in emergencies like head injury, stroke, or glaucoma when other treatments are not enough.

Can Mannitol 20% Infusion affect my body’s water and salt balance?

Yes, Mannitol 20% Infusion can change your body’s water and electrolyte levels, sometimes leading to dehydration, high or low sodium, or acid‑base imbalance. Doctors check your blood and urine regularly to keep this in control.

What happens if Mannitol 20% Infusion builds up in the body?

If Mannitol 20% Infusion is not removed properly by the kidneys, it can build up, causing too much fluid in the body, swelling, or even worsening heart or kidney problems. That is why it is given under close hospital supervision.

Can Mannitol 20% Infusion affect people with heart problems?

Yes, Mannitol 20% Infusion can cause too much fluid in the bloodstream, which may worsen heart failure or cause lung congestion. Doctors will check your heart condition carefully before giving it.

Why do doctors monitor urine output closely during Mannitol 20% Infusion?

Urine output helps doctors know if your kidneys are removing Mannitol 20% Infusion effectively. Low or no urine during treatment may mean your kidneys are not tolerating it, and the infusion might need to be stopped.

Is Mannitol 20% Infusion safe for older adults or children?

Older adults and children may be more sensitive to fluid or electrolyte imbalances caused by Mannitol 20% Infusion. The dose is adjusted carefully based on age, weight, and medical condition.

Fact Box

Chemical Class

Sugar alcohols

Habit Forming

Therapeutic Class

CARDIAC

Action Class

Osmotic Diuretics

Related lab tests

Blood Urea Nitrogen

Creatinine - Spot

Kidney Function Test

Sodium

Urine Routine & Microscopy

References

Ives HE. Diuretic Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 263.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 836-37.
Mannitol. Thetford, Norfolk: Baxter Healthcare Ltd.; 2003 [revised Jan. 2017]. [Accessed 25 Mar 2019] (online) Available from:

User feedback

Patients taking Mannitol 20% Infusion

Once A Day

36%

Once A Month

17%

Thrice A Day

15%

Twice A Day

15%

Twice A Month

Once A Week

Alternate Day

What are you using Mannitol Infusion for?

Cerebral edema (accumulation of excessive fluid in the brain)

67%

Glaucoma

27%

Others

How much was the improvement?

Excellent

53%

Average

27%

Poor

20%

What were the side-effects while using Mannitol 20% Infusion?

Headache

29%

Vomiting

14%

No Side Effect

14%

Behavioural changes

14%

Dehydration

14%

How do you take Mannitol Infusion?

With or without food

75%

With food

25%

Please rate Mannitol 20% Infusion on price

Average

83%

Expensive

17%

Want to know more

We provide you with authentic, trustworthy and relevant information

Have issue with the content

Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Albert David Ltd
Address: D' Block, 3rd Floor, Gillander House, Netaji Subhas Road, Kolkata - 700001 (WB) / 5/11, D. Gupta Lane, Kolkata 700 050, India

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Mannitol 20% Infusion

Save more with additional offers

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Mannitol Infusion

Benefits of Mannitol Infusion

Side effects of Mannitol Infusion

How to use Mannitol Infusion

How Mannitol Infusion works

All substitutes for Mannitol 20% Infusion

Manitol 20% Infusion

Fabitol 20% Infusion

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Tobramycin (Injection Route)

Tobramycin (Inhalation Route)

Tobramycin (Oral Route)

Lamivudine (Oral Route)

Atracurium (Injection Route)

Frequently asked questions

What is Mannitol 20% Infusion used for?

Who should not receive Mannitol 20% Infusion?

Is Mannitol 20% Infusion safe for people with kidney problems?

Can Mannitol 20% Infusion cause brain swelling or confusion?

What serious side effects of Mannitol 20% Infusion should I watch for?

Why is Mannitol 20% Infusion used to lower pressure in the brain and eyes?

Can Mannitol 20% Infusion affect my body’s water and salt balance?

What happens if Mannitol 20% Infusion builds up in the body?

Can Mannitol 20% Infusion affect people with heart problems?

Why do doctors monitor urine output closely during Mannitol 20% Infusion?

Is Mannitol 20% Infusion safe for older adults or children?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Blood Urea Nitrogen

Creatinine - Spot

Kidney Function Test

Sodium

Urine Routine & Microscopy

References

User feedback

Patients taking Mannitol 20% Infusion

What are you using Mannitol Infusion for?

How much was the improvement?

What were the side-effects while using Mannitol 20% Infusion?

How do you take Mannitol Infusion?

Please rate Mannitol 20% Infusion on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests