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Lupitux Injection 1
Lupitux Injection 2
Lupitux Injection 3
Lupitux Injection 4

Lupitux Injection

Cetuximab (100mg)
Genuine
Authenticity Assured
Prescription
required
Cold stored
Stored between 2-8°C

Product Summary :

Lupitux Injection is an anti-cancer medicine (EGFR blocker) that contains cetuximab. It is used to treat certain cancers of the colon and rectum and head and neck. It works by blocking signals that help cancer cells grow and survive. It is given into a vein by a doctor. Common side effects include skin reactions, headache, diarrhea and infections. Serious reactions can occur during the infusion.
 


Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 06 Nov 2026 | 01:02 AM (IST)
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20 ml Injection
Get by Monday, 9 November
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Gurgaon
 
 
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Product expires after Feb, 2027

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General Information

Contains

Cetuximab (100mg)

Marketer

Lupin Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English
Lupitux Injection 1
Lupitux Injection 2
Lupitux Injection 3
Lupitux Injection 4

Product introduction

Lupitux Injection is used in the treatment of head and neck cancer and cancer of colon and rectum. It helps to mark the cancer cells for destruction by the body's immune system.

Lupitux Injection is given as an injection under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. Do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include nausea, headache, vomiting, and skin rash. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Inform your doctor if you experience sudden difficulty in breathing, shortness of breath, fever, or chills. Regular blood tests are required to check your blood cells along with heart, liver, and electrolyte levels. It makes your skin more sun-sensitive, take precaution while stepping out.

Before taking it, tell your doctor if you have heart disease, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Lupitux Injection

  • Cancer of colon and rectum : Lupitux Injection helps treat certain types of cancer of the colon or rectum that have spread to other parts of the body. It works by blocking signals that cancer cells use to grow and survive.
  • Head and neck cancer : Lupitux Injection helps treat certain cancers of the head, neck, mouth, nose, sinuses, or throat, including cancers that are advanced, have returned, or have spread to other parts of the body.

Benefits of Lupitux Injection

Cancer of colon and rectum
Cancer of the colon and rectum, also known as colorectal cancer (CRC) or bowel cancer, is the development of cancer from two parts of the large intestine, namely, the colon or rectum. In this type of cancer, the person may notice symptoms such as blood in the stool, a change in bowel movements, weight loss, and fatigue. Lupitux Injection treats and also lowers the risk of developing further cancerous growths (polyps) and bowel cancer. It kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective medicine, but has some bothersome side effects. Consult your doctor if you have any concerns.
Head and neck cancer
Head and neck cancer includes cancer of the mouth, nose, sinuses or throat. Lupitux Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol or smoking while having this treatment and drink plenty of water to stay hydrated.

Side effects of Lupitux Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Lupitux
  • Decreased magnesium level in blood
  • Increased liver enzymes
  • Skin reaction
  • Infusion site reaction
  • Mucositis

How to use Lupitux Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Lupitux Injection works

Lupitux Injection is a monoclonal antibody that specifically binds to receptors on cancer cells. Thus it flags the cancer cells for destruction by the body's immune system.

Dosage

Lupitux Injection is given slowly into a vein by a doctor, usually once a week or once every 2 weeks. The dose you receive depends on your body size and treatment plan. It may be given alone or with chemotherapy or radiation therapy. Your doctor will decide how long you need treatment and may change or delay doses if you develop certain side effects.


 

Quick tips

  • Lupitux Injection is given as an injection into the veins under the supervision of a doctor. 
  • Tell your doctor immediately if you develop fever, chills, or breathing problems during or after the infusion, as these may be signs of an infusion reaction.
  • Report a new or worsening cough, chest pain, or shortness of breath immediately to your doctor, as Lupitux Injection can rarely cause serious lung problems.
  • Limit sun exposure during treatment and for 2 months afterward. Tell your doctor about an acne-like rash, dry or cracked skin, nail problems, or eye problems.
  • Your doctor may regularly check certain minerals in your blood, as Lupitux Injection can lower magnesium and may also affect potassium and calcium levels.
  • If you can become pregnant, use effective contraception during treatment and for 2 months after the last dose. Do not breastfeed during this period.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Lupitux Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Lupitux Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CAUTION
Lupitux Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Lupitux Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Lupitux Injection in patients with kidney disease. Please consult your doctor.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Lupitux Injection in patients with liver disease.

Interaction with drugs

Taking Lupitux with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Carboplatin (Injection Route)

Do not consume Cetuximab with Carboplatin. If concurrent use is essential, please consult your doctor. They may monitor your treatment and adjust the doses as per the observations. Cetuximab may increase the effect of Carboplatin.
Severe

Capecitabine (Oral Route)

Talk to your doctor if you notice any unusual symptoms. Capecitabine may increase the side effects of Cetuximab.
Severe

Cisplatin (Injection Route)

Do not consume Cetuximab with Cisplatin. If concurrent use is essential, please consult your doctor. They may monitor your treatment and adjust the doses as per the observations. Cetuximab may increase the metabolism of Cisplatin.
Severe

Oxaliplatin (Injection Route)

Do not consume Cetuximab with Oxaliplatin. If concurrent use is essential, please consult your doctor. They may monitor your treatment and adjust the doses as per the observations. Cetuximab may increase the rate of release of Oxaliplatin in the blood.
Moderate

Fluorouracil (Injection Route)

Talk to your doctor if you notice any unusual symptoms.Doctor may monitor your liver function. Fluorouracil may raise blood levels of Cetuximab.

Frequently asked questions

It is not a radiosensitizer, but usually used in combination with radiotherapy to treat the cancers. It is not a vesicant (irritant).
Lupitux Injection is generally administered by intravenous (IV infusion) route, with or without radiotherapy.
Yes. Lupitux Injection is a chemotherapy agent, which may cause hair loss. Please consult your doctor if you experience such side effect.
Lupitux Injection may cause a rash. Consult your doctor if it bothers you.
The duration of skin rash depends upon its type and severity. Please consult your doctor for advice..
Yes. Lupitux Injection may be used for certain head and neck cancers that have returned or spread to other parts of the body. Depending on your condition, it may be given alone or along with other cancer treatments.
A medicine to reduce the chance of an allergic reaction is given before Lupitux Injection. Serious reactions can occur during an infusion, particularly with the first dose, so you will be closely monitored.
Limit your exposure to sunlight during treatment and for 2 months after your last dose. Your skin may be more sensitive during treatment, and sun exposure may worsen skin problems.
Women who are breastfeeding are advised not to breastfeed their child during treatment and for 2 months after the last dose. Confirm with your doctor as per your treatment plan and needs.

Fact Box

Chemical Class

Peptides

Habit Forming

No

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Anti-HER1 Monoclonal Antibody

Related lab tests

References

  1. Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1736-37.
  2. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 953-54.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 239-40.
  4. Cetuximab. Feltham, Middlesex: Merck; 2004 [revised Oct. 2018]. [Accessed 26 Mar. 2019] (online) Available from:
  5. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Cetuximab. [Updated 2018 Dec 3]. [Accessed 18 Feb. 2020] (online) Available from:
  6. Cetuximab. Branchburg, NJ: Eli Lilly and Company; 2021. [Accessed 18 Feb. 2020] (online). Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Lupin Ltd
Address: 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Lupitux Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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