Lupitux Injection

Cetuximab (100mg)

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Prescription

required

Cold stored

Stored between 2-8°C

Lupitux Injection is used in the treatment of head and neck cancer and cancer of colon and rectum. It helps to mark the cancer cells for destruction by the body's immune system.

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 02 Mar 2026 | 12:39 PM (IST)

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20 ml Injection

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General Information

Contains

Cetuximab (100mg)

Marketer

Lupin Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.

The content is shown in English

Product introduction

Lupitux Injection is given as an injection under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. Do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include nausea, headache, vomiting, and skin rash. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Inform your doctor if you experience sudden difficulty in breathing, shortness of breath, fever, or chills. Regular blood tests are required to check your blood cells along with heart, liver, and electrolyte levels. It makes your skin more sun-sensitive, take precaution while stepping out.

Before taking it, tell your doctor if you have heart disease, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Lupitux Injection

Benefits of Lupitux Injection

Cancer of colon and rectum
Cancer of the colon and rectum, also known as colorectal cancer (CRC) or bowel cancer, is the development of cancer from two parts of the large intestine, namely, the colon or rectum. In this type of cancer, the person may notice symptoms such as blood in the stool, a change in bowel movements, weight loss, and fatigue. Lupitux Injection treats and also lowers the risk of developing further cancerous growths (polyps) and bowel cancer. It kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective medicine, but has some bothersome side effects. Consult your doctor if you have any concerns.

Head and neck cancer
Head and neck cancer includes cancer of the mouth, nose, sinuses or throat. Lupitux Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol or smoking while having this treatment and drink plenty of water to stay hydrated.

Side effects of Lupitux Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Lupitux

Nausea
Headache
Vomiting
Conjunctivitis
Skin rash
Diarrhea
Infusion reaction
Decreased magnesium level in blood
Increased liver enzymes

How to use Lupitux Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Lupitux Injection works

Lupitux Injection is a monoclonal antibody that specifically binds to receptors on cancer cells. Thus it flags the cancer cells for destruction by the body's immune system.

Quick tips

Lupitux Injection is given as an injection into the veins under the supervision of a doctor.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Lupitux Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Lupitux Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CAUTION

Lupitux Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

CONSULT YOUR DOCTOR

It is not known whether Lupitux Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of Lupitux Injection in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Lupitux Injection in patients with liver disease.

Interaction with drugs

Taking Lupitux with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Carboplatin (Injection Route)

Do not consume Cetuximab with Carboplatin. If concurrent use is essential, please consult your doctor. They may monitor your treatment and adjust the doses as per the observations. Cetuximab may increase the effect of Carboplatin.

Severe

Capecitabine (Oral Route)

Your doctor may monitor treatment and prescribe safer alternatives, if required.

Severe

Cisplatin (Injection Route)

Concurrent use should be avoided. If concurrent use is essential, your doctor may regularly monitor cardiac function and blood electrolyte levels.

Severe

Oxaliplatin (Injection Route)

Your doctor may monitor treatment and prescribe safer alternatives, if required.

Moderate

Fluorouracil (Injection Route)

Contact your doctor if you experience chest pain, chest tightness, difficulty breathing, and/or redness, tenderness, or peeling of the palms and soles.

Frequently asked questions

Is Lupitux Injection a chemotherapy drug?

Yes, Lupitux Injection is a cytotoxic drug that is used in the chemotherapy of cancers of colon and rectum, and head-neck cancers.

Is Lupitux Injection cytotoxic agent or vesicant or radiosensitizer?

It is not a radiosensitizer, but usually used in combination with radiotherapy to treat the cancers. It is not a vesicant (irritant).

How is Lupitux Injection administered?

Lupitux Injection is generally administered by intravenous (IV infusion) route, with or without radiotherapy.

Does Lupitux Injection cause hair loss?

Yes. Lupitux Injection is a chemotherapy agent, which may cause hair loss. Please consult your doctor if you experience such side effect.

Why does Lupitux Injection cause a rash?

Lupitux Injection may cause a rash. Consult your doctor if it bothers you.

How long does the rash last?

The duration of skin rash depends upon its type and severity. Please consult your doctor for advice..

Fact Box

Chemical Class

Peptides

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Anti-HER1 Monoclonal Antibody

Related lab tests

Carcino Embryonic Antigen

References

Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1736-37.
Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 953-54.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 239-40.
Cetuximab. Feltham, Middlesex: Merck; 2004 [revised Oct. 2018]. [Accessed 26 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Cetuximab. [Updated 2018 Dec 3]. [Accessed 18 Feb. 2020] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Lupin Ltd
Address: 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Lupitux Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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Why we need a prescription?

Lupitux Injection

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Lupitux Injection

Benefits of Lupitux Injection

Side effects of Lupitux Injection

How to use Lupitux Injection

How Lupitux Injection works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Carboplatin (Injection Route)

Capecitabine (Oral Route)

Cisplatin (Injection Route)

Oxaliplatin (Injection Route)

Fluorouracil (Injection Route)

Frequently asked questions

Is Lupitux Injection a chemotherapy drug?

Is Lupitux Injection cytotoxic agent or vesicant or radiosensitizer?

How is Lupitux Injection administered?

Does Lupitux Injection cause hair loss?

Why does Lupitux Injection cause a rash?

How long does the rash last?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Carcino Embryonic Antigen

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests