Lupibose 62.5 Tablet

Prescription Required
Manufacturer
SALT COMPOSITION
Storage
Store at room temperature (10-30°C)
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Introduction

Lupibose 62.5 Tablet is a prescription medicine used to treat pulmonary arterial hypertension (high pressure in the blood vessels that carry blood from the heart to the lungs). It even helps to improve your quality of life, exercising ability and delay in disease progression.

Lupibose 62.5 Tablet should be taken with or without food. This medicine should be used regularly to get the most benefit from it. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you.

The most common side effects of this medicine include headache, swelling of the legs and ankles, and diarrhea.  If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Some serious side effects which mean your doctor should know immediately include Anemia (low number of red blood cells) and abnormal liver function such as nausea, vomiting, dark urine, fever, and dark urine. Your doctor might check you for blood tests to check for anemia and liver function.

Before taking this medicine, let your doctor know if you have liver dysfunctioning. Inform your doctor if you are pregnant or breastfeeding. Women are suggested to use reliable contraceptive pills to avoid pregnancy and should continue even after one month of stopping the treatment. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works.

Benefits of Lupibose Tablet

In Pulmonary arterial hypertension (PAH)

Pulmonary arterial hypertension can cause shortness of breath, tiredness, dizziness, chest pain and swelling in your ankles and legs. It is caused by thickening of walls of the arteries that supply your lungs making it hard for blood to get through. Lupibose 62.5 Tablet relaxes the blood vessels and can help lower the blood pressure in the arteries of your lungs. You will be able to carry out your daily activities more easily and feel less tired or dizzy.

Side effects of Lupibose Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Lupibose

  • Headache
  • Ankle swelling
  • Edema (swelling)
  • Diarrhea
  • Anemia (low number of red blood cells)
  • Respiratory tract infection

How to use Lupibose Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lupibose 62.5 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Lupibose Tablet works

Lupibose 62.5 Tablet is an endothelin receptor blocker. It blocks the action of endothelin (a natural substance) that causes blood vessels to narrow (constrict). This narrowing increases the pressure in the blood vessels of the lungs. Lupibose 62.5 Tablet helps relax these blood vessels and increases the supply of blood to the lungs.

Safety Advice

Alcohol
UNSAFE
Lupibose 62.5 Tablet may cause excessive drowsiness with alcohol.
Pregnancy
UNSAFE
Lupibose 62.5 Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breastfeeding
CONSULT YOUR DOCTOR
Lupibose 62.5 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Lupibose 62.5 Tablet may cause side effects which could affect your ability to drive.
As Lupibose 62.5 Tablet can induce hypotension (decrease of your blood pressure) which can make you feel dizzy and this can affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Lupibose 62.5 Tablet is safe to use in patients with kidney disease. No dose adjustment of Lupibose 62.5 Tablet is recommended.
Liver
CAUTION
Lupibose 62.5 Tablet should be used with caution in patients with liver disease. Dose adjustment of Lupibose 62.5 Tablet may be needed. Please consult your doctor.
Use of Lupibose 62.5 Tablet is not recommended in patients with moderate and severe liver disease.

What if you forget to take Lupibose Tablet?

If you miss a dose of Lupibose 62.5 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Lupibose 62.5 Tablet
₹111.2/Tablet
PULVANCE 62.5 MG TABLET
Sun Pharmaceutical Industries Ltd
₹69/Tablet
38% cheaper
₹69.48/Tablet
38% cheaper
Bosenat 62.5 Tablet
Natco Pharma Ltd
₹73/Tablet
34% cheaper
₹89.71/Tablet
19% cheaper

Quick Tips

  • Your doctor has prescribed Lupibose 62.5 Tablet to treat high pressure in the blood vessels that carry blood from the heart to the lungs (the pulmonary arteries).
  • It helps improve your quality of life, exercising ability, and delay disease progression.
  • Notify your doctor if you are pregnant or planning to conceive or breastfeeding.
  • Your doctor may ask you to get routine blood tests done to check for anemia and to assess the functioning of your liver.
  • Do not drive or do anything requiring concentration until you know how Lupibose 62.5 Tablet affects you.
  • Females with reproductive potential should use a reliable form of birth control while using and 1 month after stopping Lupibose 62.5 Tablet as it is toxic to an unborn baby.
  • Inform your doctor if you notice weight gain, swelling of your arms and legs, or difficulty breathing.
  • Inform your doctor if you notice yellowing of skin/eye, dark urine, or stomach pain.

Fact Box

Chemical Class
Sulfonamide and Pyrimidine Derivative
Habit Forming
No
Therapeutic Class
CARDIAC

Interaction with Drugs

Taking Lupibose with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Clowil, Odis, Kamestin
LIFE-THREATENING
Brand(s): Fungis, EF Z, Rocflu
LIFE-THREATENING
Brand(s): No Gluco, Diabnil, D Con
LIFE-THREATENING
Brand(s): Indizole
LIFE-THREATENING

Patient Concerns

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Having high Pulmonary Atrial Hypertension
Dr. Nabajit Talukdar
Cardiology
What medicines r u on
Hiii my wife having hurt patient ( pulmonary hypertension ) she's taking pulmonext 5mg tablet but this tablet is very costly for me of Rs. 1450/- 10tab. I want to know any another tablet available in same drugs with low price
Dr. Sfurti Mann
Internal Medicine
This can't be decided online Your doctor is the best judge about your patients pulmonary hypertension
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FAQs

Q. How is Lupibose 62.5 Tablet administered?

Lupibose 62.5 Tablet is given as a tablet form and can be taken with or without food. The tablets are to be taken twice daily in the morning and evening. The exact dosage and frequency of dose will be decided by the doctor on the basis of age and weight of the patient.

Q. Are there chances of anemia with Lupibose 62.5 Tablet?

Yes, there are chances that Lupibose 62.5 Tablet may cause anemia. It can cause a dose-related decrease in hemoglobin in the blood which could lead to anemia. Regular hemoglobin check is advised while taking this medicine and consult your prescribing doctor for his advice. In some cases, blood transfusion is done to treat anemia.

Q. Can I take Lupibose 62.5 Tablet if I have liver problems?

It has been found that in some cases Lupibose 62.5 Tablet can cause liver damage in patients who are prone to have liver disease. This medicine can also lead to increased liver enzymes. Hence, it should be used with caution in prone patients or in patients with history of liver disease. Before starting the medication inform your doctor if you have had a history of liver disease.

Q. Is Lupibose 62.5 Tablet safe in pregnancy?

No, Lupibose 62.5 Tablet is not safe during pregnancy. There is evidence to show that it can cause major birth defects in the newborn baby and can harm the baby in womb. It is not advised to take Lupibose 62.5 Tablet if you are planning to become pregnant. You should use reliable contraception methods while you take Lupibose 62.5 Tablet. Consult your doctor before starting this medication or planning pregnancy.

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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Barnes PJ. Pulmonary Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1059.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 154-56.
  3. Bosentan. Beerse Belgium: Janssen-Cilag International NV; 2013 [revised Sep. 2018]. [Accessed 01 Apr. 2019] (online) Available from:External Link
  4. Bosentan. South San Francisco, California: Actelion Pharmaceuticals US, Inc.; 2001 [revised Aug. 2009]. [Accessed 23 Jan. 2019] (online) Available from:External Link
  5. Bosentan. South San Francisco, CA: Actelion Pharmaceuticals; 2001. [Accessed 01 Apr. 2019] (online) available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 01 Apr. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India
Country of Origin: India

Expires on or after: December, 2021

A licensed vendor partner from your nearest location will deliver Lupibose 62.5 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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₹945.2
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10 tablets in 1 strip
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