Lucaparib 300mg Tablet is used in the treatment of prostate and ovarian cancers. It works by stopping the repair of damaged cancer cells, which stops their further growth, and kills the damaged cancer cells.

Lucaparib 300mg Tablet can be taken with or without food, but better to have it at the same time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as advised by the doctor. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include increased liver enzymes, decreased appetite, anemia, weakness, gastrointestinal disturbance, acute myeloid leukemia (blood cancer), and nasopharyngitis (inflammation of the throat and nasal passages). Inform your doctor if you notice fever, chills, sore throat, and severe diarrhea. Regular blood tests are required to check your blood cells along with the heart, liver, and blood uric acid levels. It is advised to stay hydrated while taking this medicine to overcome diarrhea.

Before taking it, tell your doctor if you have heart disease, liver or kidney problems, or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine, so let your healthcare team know about all the medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. Effective contraception by both males and females during the treatment is important to avoid pregnancy.

Uses of Lucaparib Tablet

Benefits of Lucaparib Tablet

In Prostate cancer

Prostate gland is a small walnut-sized gland that produces seminal fluid, which nourishes and transports sperm in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Lucaparib 300mg Tablet decreases or stops the growth of cancer cells and also relieves difficulty in passing urine. This makes it easier to urinate.

In Ovarian cancer

Ovarian cancer is a cancer that begins in the female organs that produce eggs (ovaries). This type of cancer is usually detected very late and can be fatal too. It usually spreads to the pelvis and stomach. Lucaparib 300mg Tablet kills the cancer cells and also prevents the repair of damaged cancer cells. It is an effective medicine but has some side effects that may be bothersome. Consult your doctor to know about the ways that can help you avoid these side effects.

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Side effects of Lucaparib Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Lucaparib

Nasopharyngitis (inflammation of the throat and nasal passages)
Rash
Increased liver enzymes
Decreased appetite
Anemia (low number of red blood cells)
Weakness
Gastrointestinal disturbance
Myelodysplastic syndrome
Acute myeloid leukemia (blood cancer)

How to use Lucaparib Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lucaparib 300mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Lucaparib Tablet works

Lucaparib 300mg Tablet prevents (by blocking certain proteins) cancer cells from repairing their damaged DNA, causing them to die.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Lucaparib 300mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Lucaparib 300mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Lucaparib 300mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether Lucaparib 300mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

SAFE IF PRESCRIBED

Lucaparib 300mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Lucaparib 300mg Tablet is recommended.

Liver

SAFE IF PRESCRIBED

Lucaparib 300mg Tablet is safe to use in patients with liver disease. No dose adjustment of Lucaparib 300mg Tablet is recommended.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Lucaparib 300mg Tablet

₹894.37/Tablet

Bdparib 300 Tablet

BDR Pharmaceuticals Internationals Pvt

₹881.55/tablet

1% cheaper

Quick tips

Before taking Lucaparib 300mg Tablet, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.).
After starting your treatment with Lucaparib 300mg Tablet you may be at risk of infection, so try to avoid crowds or people with colds. Report fever or any other signs of infection immediately to your doctor.
Drink at least two to three-quarters of fluid every 24 hours, unless you are instructed otherwise.
To reduce nausea, take antinausea medications as prescribed by your doctor, and eat small, frequent meals.
Females who are able to become pregnant should use effective birth control during the treatment and for at least 6 months after receiving the last dose of Lucaparib 300mg Tablet.
Avoid breastfeeding during the treatment with Lucaparib 300mg Tablet and for 2 weeks after the last dose.
If you are a male with a female partner who is pregnant or able to conceive, use effective birth control (condom) during the treatment and for 3 months after the last dose of Lucaparib 300mg Tablet.
Before taking Lucaparib 300mg Tablet, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.).
After starting your treatment with Lucaparib 300mg Tablet you may be at risk of infection, so try to avoid crowds or people with colds. Report fever or any other signs of infection immediately to your doctor.
Drink at least two to three-quarters of fluid every 24 hours, unless you are instructed otherwise.
To reduce nausea, take antinausea medications as prescribed by your doctor, and eat small, frequent meals.
Females who are able to become pregnant should use effective birth control during the treatment and for at least 6 months after receiving the last dose of Lucaparib 300mg Tablet.
Avoid breastfeeding during the treatment with Lucaparib 300mg Tablet and for 2 weeks after the last dose.
If you are a male with a female partner who is pregnant or able to conceive, use effective birth control (condom) during the treatment and for 3 months after the last dose of Lucaparib 300mg Tablet.

Fact Box

Chemical Class

2-phenylindoles

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Anticancer-others

Interaction with drugs

Taking Lucaparib with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Tenofovir disoproxil fumarate (Oral Route) Moderate

Rucaparib may raise blood levels of Tenofovir disoproxil fumarate. If concurrent use is essential, watch out for symptoms such as frequent urination, nausea, diarrhea or weakness ... More

Paclitaxel (Oral Route) Moderate

Rucaparib may raise blood levels of Paclitaxel. watch out for symptoms of Paclitaxel side effects such as rash, bleeding, flushing, hair loss, nausea, vomiting or weakness and con... More

Docetaxel (Oral Route) Moderate

Rucaparib may raise blood levels of Docetaxel. If concurrent use is essential, watch out for symptoms of Docetaxel side effects such as breathlessness, constipation, edema, muscle... More

Vinorelbine (Oral Route) Moderate

Rucaparib may raise blood levels of Vinorelbine. If concurrent use is essential, watch out for symptoms such as fatigue, nausea, vomiting, diarrhea, constipation, hair loss, mouth... More

Rifaximin (Oral Route) Moderate

Rucaparib may raise blood levels of Rifaximin. watch out for symptoms of Rifaximin side effects such as diarrhea, dizziness, swelling or fatigue and consult your doctor if you exp... More

View all drug interactions

Patient concerns

Do i have prostrate cancer. Married but now having difficulty in having relation with wife. Penis not hard in the morning. Having problem with self spontaneous erection. Please help. God Bless.

Dr. Sanjay Singh Rai

Medical Oncology and Hematology

Not a symptom of prostate cancer

I have problem of frequent urination at night. My father had same at his time.Doctor told me that I am having BPH.Also I went through PSA whose result is 1.8 increased prostate gland size is 40 which came in ultrasound report .When doctor did some test by inserting his finger in my rectal area I felt abnormal pain.doctor asked me to go for a culture test so as to check which can be the best medicine for BPH for me. Kindly suggest if it can be something else like prostate cancer.

Dr. Vijay Sharnangat

Medical Oncology and Hematology

May not be prostate cancer, it is only begnin enlargement of prostate.

Related lab tests

Prostate Specific Antigen (Free) PSA

Prostate Specific Antigen (Total) PSA

Related ayurvedic ingredients

Green Tea

Garlic

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Marketer details

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Country of origin: India

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