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Lucaparib 300mg Tablet 1
Lucaparib 300mg Tablet 2

Lucaparib 300mg Tablet

Rucaparib (300mg)
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Lucaparib 300mg Tablet is used in the treatment of prostate and ovarian cancers. It works by stopping the repair of damaged cancer cells, which stops their further growth, and kills the damaged cancer cells.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 31 Aug 2026 | 02:14 PM (IST)
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Payment

Online only

Free Return

within 7 days

Expiry after

Dec, 2026

Price Info

The price displayed is the MRP (inclusive of applicable taxes). Any additional fee (shipping, handling and/or platform fee, etc.) will be disclosed before you complete your purchase.

The content is shown in English
Lucaparib 300mg Tablet 1
Lucaparib 300mg Tablet 2

Product introduction

Lucaparib 300mg Tablet can be taken with or without food, but better to have it at the same time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as advised by the doctor. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include increased liver enzymes, decreased appetite, anemia, weakness, gastrointestinal disturbance, acute myeloid leukemia (blood cancer), and nasopharyngitis (inflammation of the throat and nasal passages). Inform your doctor if you notice fever, chills, sore throat, and severe diarrhea. Regular blood tests are required to check your blood cells along with the heart, liver, and blood uric acid levels. It is advised to stay hydrated while taking this medicine to overcome diarrhea.

Before taking it, tell your doctor if you have heart disease, liver or kidney problems, or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine, so let your healthcare team know about all the medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. Effective contraception by both males and females during the treatment is important to avoid pregnancy.

Uses of Lucaparib Tablet

Benefits of Lucaparib Tablet

Prostate cancer
Prostate gland is a small walnut-sized gland that produces seminal fluid, which nourishes and transports sperm in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Lucaparib 300mg Tablet decreases or stops the growth of cancer cells and also relieves difficulty in passing urine. This makes it easier to urinate.
Ovarian cancer
Ovarian cancer is a cancer that begins in the female organs that produce eggs (ovaries). This type of cancer is usually detected very late and can be fatal too. It usually spreads to the pelvis and stomach. Lucaparib 300mg Tablet kills the cancer cells and also prevents the repair of damaged cancer cells. It is an effective medicine but has some side effects that may be bothersome. Consult your doctor to know about the ways that can help you avoid these side effects.

Side effects of Lucaparib Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Lucaparib
  • Increased liver enzymes
  • Decreased appetite
  • Anemia (low number of red blood cells)
  • Weakness
  • Gastrointestinal disturbance
  • Myelodysplastic syndrome
  • Acute myeloid leukemia (blood cancer)
  • Nasopharyngitis (inflammation of the throat and nasal passages)
  • Rash

How to use Lucaparib Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lucaparib 300mg Tablet may be taken with or without food.

How Lucaparib Tablet works

Lucaparib 300mg Tablet prevents (by blocking certain proteins) cancer cells from repairing their damaged DNA, causing them to die.

Quick tips

  • Before taking Lucaparib 300mg Tablet, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.).
  • After starting your treatment with Lucaparib 300mg Tablet you may be at risk of infection, so try to avoid crowds or people with colds. Report fever or any other signs of infection immediately to your doctor.
  • Drink at least two to three-quarters of fluid every 24 hours, unless you are instructed otherwise.
  • To reduce nausea, take antinausea medications as prescribed by your doctor, and eat small, frequent meals.
  • Females who are able to become pregnant should use effective birth control during the treatment and for at least 6 months after receiving the last dose of Lucaparib 300mg Tablet.
  • Avoid breastfeeding during the treatment with Lucaparib 300mg Tablet and for 2 weeks after the last dose.
  • If you are a male with a female partner who is pregnant or able to conceive, use effective birth control (condom) during the treatment and for 3 months after the last dose of Lucaparib 300mg Tablet.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Lucaparib 300mg Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Lucaparib 300mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Lucaparib 300mg Tablet during breastfeeding is not available. Please consult your doctor.
Driving

Driving

UNSAFE
Lucaparib 300mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Lucaparib 300mg Tablet in patients with kidney disease. Please consult your doctor.
Liver

Liver

CAUTION
Lucaparib 300mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
All

Interaction with drugs

Taking Lucaparib with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate

Agomelatine (Oral Route)

If concurrent use is essential, watch out for symptoms such as headache, nausea, dizziness, fatigue, anxiety, difficulty in sleeping, back pain or abdominal pain and consult your doctor if you experience them. They may adjust the doses as per the observations. Rucaparib may raise blood levels of Agomelatine.
Moderate

Temsirolimus (Injection Route)

Please consult with your doctor regarding required precautions. If you observe any sign of bleeding, please inform your doctor.
Moderate

Rifaximin (Oral Route)

watch out for symptoms of Rifaximin side effects such as diarrhea, dizziness, swelling or fatigue and consult your doctor if you experience them. They may adjust the doses as per the observations. Rucaparib may raise blood levels of Rifaximin.
Moderate

Paclitaxel (Injection Route)

watch out for symptoms of Paclitaxel side effects such as rash, bleeding, flushing, hair loss, nausea, vomiting or weakness and consult your doctor if you experience them. They may adjust the doses as per the observations. Rucaparib may raise blood levels of Paclitaxel.
Moderate

Docetaxel (Injection Route)

If concurrent use is essential, watch out for symptoms of Docetaxel side effects such as breathlessness, constipation, edema, muscle pain or weakness and consult your doctor if you experience them. They may adjust the dose of Docetaxel accordingly. Rucaparib may raise blood levels of Docetaxel.

Frequently asked questions

Lucaparib 300mg Tablet is usually used to treat certain types of cancer, including specific ovarian, fallopian tube, primary peritoneal, and prostate cancers. It may also be used to help keep cancer under control after a good response to previous treatment. Your doctor will determine whether this medicine is suitable based on your cancer type and treatment history.
Lucaparib 300mg Tablet contains Rucaparib, a targeted anticancer medicine. It works by blocking proteins that help damaged cancer cells repair themselves. As a result, cancer cells become less able to survive and multiply, which can help slow the growth and spread of the cancer.
No. Lucaparib 300mg Tablet is a targeted cancer therapy rather than traditional chemotherapy. It works in a more specific way by targeting certain pathways that cancer cells use to repair damage. However, like other cancer treatments, it can still cause side effects and requires regular monitoring.
The response to cancer treatment varies from person to person. Some individuals may notice improvement in symptoms within a few weeks, while for others the benefits are mainly seen through scans, blood tests, and other medical assessments. Continue taking the medicine exactly as advised by your doctor.
Yes. In some individuals, Lucaparib 300mg Tablet may be used for an extended period to help keep cancer under control, especially if it is working well and side effects remain manageable. Your doctor will regularly assess your response to determine how long treatment should continue.
Your doctor may use scans, blood tests, physical examinations, and discussions about your symptoms to assess how well the treatment is working. These regular check-ups help track the response of the cancer and guide future treatment decisions.
Some individuals may experience side effects such as tiredness, nausea, changes in appetite, stomach discomfort, or changes in taste during the first few weeks. Not everyone experiences the same effects, and many side effects can be managed with appropriate medical support.
Tiredness is one of the more commonly reported effects of cancer treatment, including Lucaparib 300mg Tablet. The medicine can affect normal cells as well as cancer cells, which may contribute to fatigue. Getting adequate rest, staying hydrated, and maintaining good nutrition may help, but speak with your doctor if the tiredness becomes severe.
Yes. Some individuals may experience nausea, vomiting, changes in taste, or a reduced appetite while taking Lucaparib 300mg Tablet. Eating small, frequent meals and staying hydrated may help. Contact your doctor if these symptoms become severe or make it difficult to eat or drink.
Cancer can behave differently in different individuals. In some cases, the disease may remain controlled after treatment, while in others it may return or progress over time. Regular follow-up appointments help your doctor monitor your condition and identify any changes as early as possible.
Tell your doctor about all medicines, supplements, and herbal products you are taking. Some medicines may affect how Lucaparib 300mg Tablet works or increase the risk of side effects. Sharing your complete medication history helps ensure your treatment remains safe and effective.
Several factors can influence treatment outcomes, including the type of cancer, its stage, genetic characteristics of the tumour, overall health, and how consistently the medicine is taken. Regular follow-up visits help your doctor evaluate your response and make any necessary adjustments.
Contact your doctor immediately if you develop severe or persistent tiredness, unusual bleeding or bruising, frequent infections, high fever, severe shortness of breath, chest pain, or any sudden worsening of your overall health. These symptoms may require urgent medical evaluation.
Contact your doctor if you experience troublesome side effects, worsening symptoms, severe nausea or vomiting, persistent fatigue, signs of infection, unusual bleeding, or any symptoms that interfere with your daily activities. Early medical attention can help manage side effects and keep treatment on track.

Fact Box

Chemical Class

2- phenylindoles

Habit Forming

No

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Other Anticancer Agents
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Lupin Ltd
Address: 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Lucaparib 300mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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