Lobel Injection

Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS

Last updated on 02 Feb 2026 | 07:41 PM (IST)

Lobel Injection is a medicine used in the urgent treatment of hypertensive emergency (severely increased blood pressure). It also helps to treat severe hypertension in pregnancy, when rapid control of blood pressure is essential.

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General Information

Contains

Labetalol (5mg/ml)

Marketer

Biosam Life Science Private Limited

Storage

Store below 25°C

The content is shown in English

Product introduction

Lobel Injection brings about an immediate reduction in blood pressure and the workload of the heart. It is administered by a doctor and requires continuous blood pressure monitoring.

Common side effects of this medicine include dizziness, fatigue, nausea, vomiting, paresthesia, impotence, edema, and cold fingers or toes. Let your doctor know if they persist or get worse. They may be able to suggest ways to prevent or reduce the side effects.

Before taking it, let your doctor know if you are suffering from any kidney or liver disease. If you are pregnant or breastfeeding then you should always inform the doctor. Lobel Injection brings about an immediate reduction in blood pressure and the workload of the heart. It is administered by a doctor and requires continuous blood pressure monitoring.

Uses of Lobel Injection

Treatment of Hypertensive emergency

Benefits of Lobel Injection

Treatment of Hypertensive emergency
Lobel Injection blocks the effect of some chemicals on your heart and blood vessels. This slows down the heart rate and helps the heart beat with less force thereby lowering your blood pressure. This medicine is injected into a vein under the supervision of a doctor. It is used for immediate reduction of very high blood pressure (hypertensive emergency). A controlled blood pressure reduces the risk of having a heart attack, stroke, or kidney problems.

Side effects of Lobel Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Lobel

Dizziness
Vomiting
Fatigue
Impotence
Paresthesia (tingling or pricking sensation)
Nausea
Edema (swelling)
Cold extremities

How to use Lobel Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Lobel Injection works

Lobel Injection is an alpha and beta blocker. It works by slowing down the heart rate and relaxing blood vessels which makes the heart more efficient at pumping blood around the body.

All substitutes for Lobel Injection

For information purposes only. Consult a doctor before taking any medicine.

Lobetajet Injection

by Suncure Lifescience Pvt Ltd

₹187.24/injection

11% cheaper

Beta-L Injection

by Wohltat Lifesciences

₹208.13/injection

1% cheaper

Quick tips

It is given as an injection into veins or as drip under the supervision of a medical professional.
Check your blood pressure 1 week after starting Lobel Injection, and inform your doctor if it has not improved.
Lobel Injection may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
It may cause you to feel lightheaded or weak especially when you stand up (orthostatic hypotension). Rise slowly if you have been sitting or lying down.
It is best to avoid drinking alcohol while taking Lobel Injection as it may make the side effects worse.
Do not stop taking Lobel Injection suddenly as it can cause your blood pressure to rise suddenly, thereby increasing the risk of heart attack and stroke.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Lobel Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Lobel Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CAUTION

Lobel Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

UNSAFE

Lobel Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Lobel Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.
However, talk to your doctor if you have any underlying kidney disease. Regular monitoring of blood pressure is recommended for better dose adjustment.

Liver

CAUTION

Lobel Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Lobel with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Aminophylline (Oral Route)

Do not consume Aminophylline with Labetalol.

Life-threatening

Theophylline (Oral Route)

Do not use Labetalol with Theophylline in any form if you have asthma or breathing issues, as it may result in excessive breathlessness or coughing.

Life-threatening

Theophylline (Injection Route)

Do not use Labetalol with Theophylline in any form if you have asthma or breathing issues, as it may result in excessive breathlessness or coughing.

Severe

Adrenaline (Injection Route)

watch out for symptoms such as breathlessness, fatigue, drowsiness, sedation or faintness or vomiting and consult your doctor if you experience them. Labetalol may reduce efficacy of Adrenaline.

Severe

Diltiazem (Oral Route)

watch out for symptoms such as breathlessness, fatigue, drowsiness, sedation or faintness or vomiting and consult your doctor if you experience them.

Frequently asked questions

Is Lobel Injection safe?

Lobel Injection is generally considered a safe medicine if it is taken as directed by the doctor. The side effects that result with use of Lobel Injection occur during the first few weeks of treatment and disappear with time.

Why is Lobel Injection used in pregnancy?

It is important to appropriately treat high blood pressure in pregnancy. Studies have shown that poorly controlled high blood pressure in pregnancy can lead to an increased risk of certain birth defects, stillbirth, reduced growth of the baby within the womb, and premature birth. For some women with high blood pressure, treatment with Lobel Injection in pregnancy might be considered to be the best option. Your doctor is the best person to help you decide what is right for you and your baby.

Does Lobel Injection cause itching?

Yes, itchy skin, a rash or tingly scalp are common side effects of Lobel Injection. Speak to your doctor if the itchiness or rash gets worse or lasts for more than a week.

Is it safe to use Lobel Injection in patients with diabetes?

Diabetic patients while using Lobel Injection should regularly check the blood sugar levels. Lobel Injection may make it difficult to recognize the warning signs of low blood sugar such as shaking and a racing heartbeat. Consult your doctor if the blood sugar levels are reduced while taking Lobel Injection.

Does Lobel Injection affect heart rate?

Lobel Injection slows down your heart rate and makes it easier for your heart to pump blood around your body. Your doctor may regularly check your blood pressure and pulse (heart rate) during therapy to determine your response to the medicine.

Fact Box

Chemical Class

Salicylamides

Habit Forming

Therapeutic Class

CARDIAC

Action Class

Alpha & beta blocker

References

Westfall TC, WestfallIn DP. Adrenergic Agonists and Antagonists. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 328-29.
Benowitz NL. Antihypertensive Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 176-77.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 764-65.
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 19 Mar. 2019] (online) Available from:
Labetalol hydrochloride [Prescribing Information]. Lake Forest, IL: Hospira, Inc.; 2018. [Accessed 20 Feb. 2024] (online) Available from:
National Health Service (NHS). Side effects of labetalol. [Accessed 20 Feb. 2024]. [Last reviewed: 7 Mar 2022]. (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Biosam Life Science Private Limited
Address: G-9, 222, KARADVA ROAD, DINDOLI, SURAT, GUJARAT, PIN- 394210, INDIA, MOB- 9470216982, 9504896445

Vendor Details

Country of origin: India

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Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

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Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Lobel Injection

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Lobel Injection

Benefits of Lobel Injection

Side effects of Lobel Injection

How to use Lobel Injection

How Lobel Injection works

All substitutes for Lobel Injection

Lobetajet Injection

Beta-L Injection

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Aminophylline (Oral Route)

Theophylline (Oral Route)

Theophylline (Injection Route)

Adrenaline (Injection Route)

Diltiazem (Oral Route)

Frequently asked questions

Is Lobel Injection safe?

Why is Lobel Injection used in pregnancy?

Does Lobel Injection cause itching?

Is it safe to use Lobel Injection in patients with diabetes?

Does Lobel Injection affect heart rate?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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