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Labetalol is used to treat severe high blood pressure in emergency situations like during pregnancy, during surgery or hypertension episodes following a heart attack.

How it works

Labetalol belongs to a class of medication called beta-blockers. It relaxes the blood vessels and reduces heart rate to improve the blood flow and decrease the blood pressure.

Common side effects

Nausea, Pain, Numbness, Heart failure, Psoriasis, Blurred vision, Cardiac arrest, Cramping pain, Decreased blood pressure, Depression, Dizziness, Shortness of breath, Asthma, Difficulty in urination, Fatigue, Fever, Headache, Increased potassium level in blood, Impotence, Inability to empty the urinary bladder, Itching, Limb swelling, Loss of muscle mass, Nose bleed, Nose pain, Sore throat, Rash, Tachycardia, Tingling sensation, Vomiting, Weakness, Worsening of heart failure, Yellow discoloration of skin, Yellow discoloration of eye


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Expert advice

  • Do not take labetalol, if are allergic to labetalol or other beta-blockers or any of the other ingredients of the tablet.
  • Consult your doctor before taking labetalol, if you are taking any other medication for high blood pressure or heart condition or other beta blockers.
  • Avoid taking labetalol, if you are breastfeeding or pregnant.
  • Do not take labetalol, if you are receiving a medical procedure for detection of tumors like MIBG scintigraphy.
  • Avoid taking labetalol, if you have scaly pink patches on the skin (psoriasis).
  • Do not drive or operate machines, if you have just begun taking labetalol or have had a change of dose, as labetalol may cause dizziness or tiredness.

Frequently asked questions


Q. Is labetalol a blood thinner/ diuretic/ vasodilator/ water pill/ addictive?
Labetalol is not a blood thinner/ diuretic/ vasodilator/ water pill/ addictive. It is a beta blocker used for reduction of blood pressure.
Q. Can I take labetalol with ibuprofen/ tylenol/ benadryl/ aspirin/ tums/ paracetamol/ aleve/ Sudafed/ phentermine?
Labetalol is not known to interact with Benadryl (anti-allergy)/ tums (antacid)/ Sudafed (cough medication)/ phentermine (appetite suppressant). Labetalol is known to interact with ibuprofen (pain killer)/ tylenol (pain killer) / aspirin (pain killer)/ paracetamol/ aleve (pain killer). Labetalol interacts with a variety of drugs and hence the doctor’s advice must be strictly followed on taking any drug along with it. 
Q. Does labetalol cause blood sugar/weight gain/affect heart rate/insomnia/weight loss/ constipation/ frequent urination?
Labetalol is known to cause blood sugar/ weight gain/ affect heart rate. It is not usually known to cause insomnia/ weight loss/ constipation/ frequent urination. If any side effect is observed while on therapy with labetalol please inform the doctor immediately.

Content on this page was last updated on 04 October, 2016, by Dr. Varun Gupta (MD Pharmacology)