Liofen 25 Tablet

Written By Dr. Lipika Khurana, PGDHHM, BDS

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 23 Jan 2026 | 10:15 AM (IST)

Liofen 25 Tablet is a muscle relaxer. It is used to treat muscular symptoms such as rigidity, tension, and stiffness that may occur due to various conditions such as cerebral palsy, multiple sclerosis, motor neuron disease, or injury to the head, brain, or spine.

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General Information

Contains

Baclofen (25mg)

Marketer

Sun Pharmaceutical Industries Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Liofen 25 Tablet can be taken with food. In general, you should try to use the smallest amount necessary to control your symptoms, for the shortest possible time. You should take this medicine regularly while you need it. Try not to miss doses as this will make the medicine less effective.

Some common side effects of this medicine include fatigue, weakness, drowsiness, and dizziness. If any of these side effects do not go away or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.

To make sure it is safe for you, before taking this medicine, let your doctor know if you have any medical conditions or disorders. You should also tell your doctor all the other medicines you are using or taking. Pregnant and breastfeeding women should consult their doctors before using this medicine.

Uses of Liofen Tablet

Muscle relaxation

Benefits of Liofen Tablet

Muscle relaxation
Liofen 25 Tablet is a muscle relaxant that is used to relieve rigidity, inflammation, and swelling in conditions that affect skeletal muscles. It works by blocking chemical messengers in the brain that are responsible for such symptoms. It effectively relieves muscle stiffness or spasm, thereby improving muscle movement.

Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Side effects of Liofen Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Liofen

Dizziness

How to use Liofen Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Liofen 25 Tablet should be taken with or after food.

How Liofen Tablet works

Liofen 25 Tablet is a muscle relaxant. It works on the brain and spinal cord to relieve muscle stiffness or spasm maintaining the strength of the muscles. This relieves pain and improves movement of muscles.

All substitutes for Liofen 25 Tablet

For information purposes only. Consult a doctor before taking any medicine.

Lioresal 25 Tablet

by Novartis India Ltd

₹41.3/tablet

12% costlier

Baclof 25 Tablet

by Intas Pharmaceuticals Ltd

₹40.1/tablet

8% costlier

Quick tips

Liofen 25 Tablet provides relief from rigidity, tension and stiffness in muscles (spasticity) that may occur due to various conditions affecting the nervous system.
Liofen 25 Tablet should be taken during meals with a little liquid.
Liofen 25 Tablet may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
Avoid consuming alcohol when taking Liofen 25 Tablet as it may cause excessive drowsiness.
Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
Do not stop taking it suddenly without talking to your doctor if you've been on it for a long time.
Liofen 25 Tablet provides relief from rigidity, tension and stiffness in muscles (spasticity) that may occur due to various conditions affecting the nervous system.
Take it with or after food or a glass of milk.
Liofen 25 Tablet may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
Avoid consuming alcohol when taking Liofen 25 Tablet as it may cause excessive drowsiness.
Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
Do not stop taking it suddenly without talking to your doctor if you've been on it for a long time.

Safety advice

Alcohol

CAUTION

Alcohol should be used with caution while taking Liofen 25 Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Liofen 25 Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CAUTION

Liofen 25 Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

UNSAFE

Liofen 25 Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Liofen 25 Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Liofen 25 Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Liofen with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Tramadol (Injection Route)

If concurrent use is essential, your doctor may monitor your respiratory and cardiovascular functions along with your overall treatment and adjust the doses as per the observations.

Moderate

Trihexyphenidyl (Injection Route)

Talk to your doctor if you notice any unusual symptoms.

Moderate

Alfuzosin (Oral Route)

If concurrent use is essential, watch out for symptoms such as dizziness, fainting, blurred vision, nausea, fatigue, confusion, cold or clammy skin, shallow breathing or rapid pulse and consult your doctor if you experience them. They may adjust the doses as per the observations.

Moderate

Amlodipine (Oral Route)

Moderate

Atenolol (Oral Route)

Frequently asked questions

Can Liofen 25 Tablet make you sleepy?

Yes, Liofen 25 Tablet can cause sleepiness. It can make a person dizzy due to its sedative effect. It can also affect vision and therefore you should avoid driving and using heavy machinery until and unless you know how Liofen 25 Tablet affects you.

Does Liofen 25 Tablet help anxiety?

Though Liofen 25 Tablet is not approved to treat anxiety disorders, it has been observed in some studies that it is effective in treating stress which occurs after a trauma.

Can I take Liofen 25 Tablet if I have a liver problem?

If you have a liver problem then you need to be cautious while taking Liofen 25 Tablet. This is because the medicine may increase the production of liver enzymes. Hence, regular laboratory examination of liver enzymes is required while taking this medicine as advised by your doctor.

Does Liofen 25 Tablet have any effect on kidneys?

Liofen 25 Tablet may cause side effects in patients with normal kidney function which include excessive day time urination (pollakiuria), burning sensation while urinating (dysuria), and loss of bladder control (urinary incontinence). Generally, a lower dose of this medicine is prescribed if a person has abnormally functioning kidneys or if a person is on dialysis.

How should Liofen 25 Tablet be taken?

Take Liofen 25 Tablet exactly as directed by your doctor. If a person experiences nausea while taking Liofen 25 Tablet then it should be consumed with food or milk. However, for night cramps, it would be best to use the medicine at night time or 1 hour before doing specific tasks like physiotherapy or washing.

Fact Box

Chemical Class

Gamma Amino Acids Derivative

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Action Class

Centrally Acting Skeletal Muscle Relaxants

References

White PF, Katzung BG. Skeletal Muscle Relaxants. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 463.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 121-23.
Baclofen. Camberley, Surrey: Novartis Pharmaceuticals UK Ltd.; 2001 [revised 22 Dec. 2017]. [Accessed 23 Jan. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 02 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:
Baclofen [Package Leaflet]. Basel, Switzerland: Novartis Pharma AG; 2021. [Accessed 09 Jun, 2023] (online) Available from:
Baclofen. Athens, GA: Metacel Pharmaceuticals, LLC; 2019. [Accessed 08 Jan, 2026] (online). Available from:

User feedback

Patients taking Liofen 25 Tablet

Thrice A Day

80%

Once A Day

20%

What are you using Liofen Tablet for?

Muscle relaxation

75%

Hiccups

25%

How much was the improvement?

Excellent

78%

Average

22%

What were the side-effects while using Liofen 25 Tablet?

No Side Effect

100%

How do you take Liofen Tablet?

With food

100%

Please rate Liofen 25 Tablet on price

Expensive

100%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Sun Pharmaceutical Industries Ltd
Address: Khasra No. 1335-1340,Near EPIP- I, Vill - Bhatoli Kalan ,Baddi, Solan, Himachal Pradesh, 173205 || Plot no 107/108,Namli block , Ranipool, East Sikkim 737135

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Liofen 25 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Liofen 25 Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Liofen Tablet

Benefits of Liofen Tablet

Side effects of Liofen Tablet

How to use Liofen Tablet

How Liofen Tablet works

All substitutes for Liofen 25 Tablet

Lioresal 25 Tablet

Baclof 25 Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Tramadol (Injection Route)

Trihexyphenidyl (Injection Route)

Alfuzosin (Oral Route)

Amlodipine (Oral Route)

Atenolol (Oral Route)

Frequently asked questions

Can Liofen 25 Tablet make you sleepy?

Does Liofen 25 Tablet help anxiety?

Can I take Liofen 25 Tablet if I have a liver problem?

Does Liofen 25 Tablet have any effect on kidneys?

How should Liofen 25 Tablet be taken?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

User feedback

Patients taking Liofen 25 Tablet

What are you using Liofen Tablet for?

How much was the improvement?

What were the side-effects while using Liofen 25 Tablet?

How do you take Liofen Tablet?

Please rate Liofen 25 Tablet on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

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