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    Amlodipine

    Information about Amlodipine

    Amlodipine uses

    Amlodipine is used in the treatment of Hypertension (High blood pressure) and Angina (Heart related chest pain).

    How amlodipine works

    Amlodipine is a calcium channel blocker. It works by relaxing blood vessels which makes the heart more efficient at pumping blood throughout the body.

    Common side effects of amlodipine

    Fatigue, Ankle swelling, Sleepiness, Flushing (sense of warmth in the face, ears, neck and trunk), Headache, Nausea, Dizziness, Palpitations, Edema (swelling), Abdominal pain
    Content Details
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    Written By
    Dr. Betina Chandolia
    Writing in Sciences, PGCCL
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    Reviewed By
    Dr. Varun Gupta
    MD (Pharmacology), MBBS
    Last updated on:
    22 May 2019 | 11:14 AM (IST)
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    Expert advice for Amlodipine

    • You have been prescribed Amlodipine to improve your blood pressure and/or to reduce the number and severity of angina attacks.
    • Lowering blood pressure reduces the chance of future heart attack & stroke.
    • Take it at the same time every day to help you remember to take it.
    • A sudden drop in your blood pressure may occur, especially when you first start taking Amlodipine. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
    • It can cause ankle or foot swelling. Raise your legs while you are sitting down. Talk to your doctor if it does not go away.

    Frequently asked questions for Amlodipine

    Amlodipine

    Q. What is Amlodipine used for?

    Amlodipine is indicated for the treatment of high blood pressure (hypertension), angina pectoris (pain in the chest caused by blockages in the arteries leading to the heart) or chest pain classed as vasospastic angina pectoris (or Prinzmetal’s angina).

    Q. Is Amlodipine a calcium channel blocker and how does it works?

    Amlodipine is a calcium channel blocker. In patients with high blood pressure, it works by relaxing blood vessels, so that blood passes through them more easily. In patients with angina, it works by improving blood supply to the heart muscle, which then receives more oxygen, and hence, prevents chest pain. It does not provide immediate relief of chest pain from angina.

    Q. Is Amlodipine safe?

    Amlodipine is safe if used at prescribed doses for the prescribed duration as advised by your doctor.

    Q. Can I take Amlodipine at night?

    Amlodipine can be taken at night. You should take Amlodipine at the same time each day with a glass of water.

    Q. Can I take Amlodipine and aspirin?

    Amlodipine can be taken with aspirin. No drug-drug interactions have been reported between the two. However, interactions can occur. Please consult your doctor before taking the two medicines together.

    Q. Can I take Amlodipine with sildenafil?

    Both Amlodipine and sildenafil cause a lowering the blood pressure. So, taking the two medicines together could be harmful. Please consult your doctor before taking them together.

    Q. Is Amlodipine safe for kidneys?

    Amlodipine is not known to damage kidneys. However, Amlodipine can cause urinary disorders like difficulty in passing urine, increased the need to urinate at night, increased number of times of passing urine as an uncommon side effect.

    Q. Does Amlodipine cause tachycardia?

    Amlodipine can rarely cause changes in heart rate, which can be an increase (tachycardia) or a decrease in heart rate (bradycardia) or an irregular heart rate. Please consult your doctor if you experience any changes in your heart rate while taking Amlodipine.

    Q. Does Amlodipine cause pedal edema (swelling of the ankles)?

    Amlodipine can cause pedal edema (swelling of the ankles). Please consult your doctor if you have pedal edema while taking Amlodipine.

    Q. Does Amlodipine increase creatinine?

    Amlodipine has not been reported to increase creatinine levels. Please consult your doctor if you have increased creatinine levels while taking Amlodipine as it requires proper diagnosis and management.

    Q. Does Amlodipine cause erectile dysfunction?

    Erectile dysfunction is an uncommon side effect of Amlodipine. Please consult your doctor if you experience erectile dysfunction when you are taking Amlodipine.

    Q. Does Amlodipine cause weight gain?

    Amlodipine can cause changes in weight, it can either cause weight gain or weight loss. However, these changes are very rare. Please consult your doctor if you experience a change in weight while taking Amlodipine.

    Q. Does Amlodipine cause joint pain (arthralgia)?

    Amlodipine can cause joint pain (arthralgia). Please consult your doctor if you experience excessive joint pains while taking Amlodipine.

    Q. Does Amlodipine cause cough?

    Amlodipine can cause cough, but it is a very rare side effect. Please consult your doctor if you experience excessive coughing while taking Amlodipine.

    Q. Does Amlodipine cause dry mouth?

    Amlodipine can cause dry mouth as an uncommon side effect. Please consult your doctor if you experience excessive dryness of mouth after taking Amlodipine.

    Q. Can I take Amlodipine without food?

    Amlodipine can be taken before or after food and drinks. Amlodipine should be taken same time each day with a glass of water. Do not take Amlodipine with grapefruit juice.

    Q. Can I take Amlodipine with ramipril?

    Amlodipine and ramipril both have a blood pressure lowering effect. So, taking both the medicines together can be harmful. Please consult your doctor before taking the two medicines together.

    Q. Can I take Amlodipine with simvastatin?

    Amlodipine can increase the levels of simvastatin, causing an increased tendency towards myopathy (muscle pain) and rhabdomyolysis (increased breakdown of muscle). The dose of simvastatin may need to be reduced when giving along with Amlodipine . Please consult your doctor.

    Content on this page was last updated on 22 May, 2019, by Dr. Varun Gupta (MD Pharmacology)