Linofit DS 100mg is an antibiotic medicine. It helps cure a wide range of serious infections caused by resistant bacteria. These may include infections affecting the skin, soft tissues, bones, brain, heart, urinary tract, lungs, and blood. It also aids in the treatment of resistant tubercular infections.

Give Linofit DS 100mg to your child orally, preferably at a fixed time, either before or after meals. In case your child develops a stomach upset, prefer giving it with meals. Adhere to the dose, time, and way prescribed by the doctor as that depends on the type and severity of the infection, your child’s age, and body weight. If your child vomits within 30 minutes of intake, repeat the same dose but do not double dose if it's time for the next dose.

Taking this medicine may sometimes cause minor and temporary side effects. These include nausea, vomiting, diarrhea, headache, and low blood cell count. These side effects almost always subside within a few days. However, in case these side effects persist or bother your child, it would be best to consult your child’s doctor without any delay.

Your child’s doctor should be aware of your child’s complete medical history, including any previous episode of allergy, heart problem, liver impairment, blood disorder, eye disorder, and kidney malfunction. Do tell the doctor if your child is taking any other medicine too. This information is critical for dose alterations and for planning your child’s overall treatment.

Uses of Linofit DS 100mg in children

Treatment of Resistant Tuberculosis (TB)
Treatment of Severe bacterial infections

Benefits of Linofit DS 100mg for your child

In Treatment of Resistant Tuberculosis (TB)

In multidrug-resistant (MDR) tuberculosis, the causative bacteria produce an enzyme that makes the antibiotics ineffective. As a result, the bacteria become resistant to the antibiotic being used for treatment. Linofit DS 100mg is effective in treating MDR tuberculosis and Extensively Drug-resistant tuberculosis (XDR-TB). Linofit DS 100mg is not the first medicine that the doctor gives to treat tuberculosis. It is given only if the child suffers from resistant-tubercular infection.

In Treatment of Severe bacterial infections

Linofit DS 100mg works by killing bacteria which can cause serious infections. It is used to treat many different types of bacterial infections such as infections of lungs (pneumonia), skin, and soft tissues. This medicine usually makes you feel better very quickly but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.

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Side effects of Linofit DS 100mg in children

Linofit DS 100mg does not pose serious side effects and is well-tolerated by children. In case the side effects do occur, they’re likely to subside once the body adapts to the medicine. Consult your child’s doctor if these side effects persist or bother your child. The most common side effects include-

Common side effects of Linofit DS

Decreased blood pressure
Vomiting
Headache
Nausea
Decreased blood cells (red cells, white cells, and platelets)
Diarrhea

How can I give Linofit DS 100mg to my child?

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Linofit DS 100mg may be taken with or without food, but it is better to take it at a fixed time.
Avoid Linofit DS 100mg with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.

How Linofit DS Oral Suspension works

Linofit DS 100mg is an antibiotic. It stops bacterial growth by preventing the synthesis of essential proteins required by bacteria to carry out vital functions.

Safety advice

Kidney

SAFE IF PRESCRIBED

Linofit DS 100mg is safe to use in patients with kidney disease. No dose adjustment of Linofit DS 100mg is recommended.
However, Linofit DS 100mg must be used with caution in children with severe kidney disease. Dose modification may be required in severe kidney disease.

Liver

SAFE IF PRESCRIBED

Linofit DS 100mg is safe to use in patients with liver disease. No dose adjustment of Linofit DS 100mg is recommended.
However, Linofit DS 100mg should be used with caution in children with severe liver disease as it can be a potential threat to liver functions although not very common.

What if I forget to give Linofit DS 100mg to my child?

There is no need to panic. You can give the medicine as soon as you remember unless your child’s doctor has advised a specific regime for your child. In case of any confusion, do consult your doctor, do not double the dose to catch up.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Linofit DS 100mg

₹90.2/Oral Suspension

Lizoforce Dry Syrup

Mankind Pharma Ltd

₹137.5/oral suspension

48% costlier

Megazolid 100 Dry Syrup

Aristo Pharmaceuticals Pvt Ltd

₹145/oral suspension

56% costlier

Lizomac DS Dry Syrup

Macleods Pharmaceuticals Pvt Ltd

₹154/oral suspension

65% costlier

Henzolid 100 Dry Syrup

Henin Lukinz Pvt Ltd

₹121/oral suspension

30% costlier

Maxolid DS Dry Syrup

Macleods Pharmaceuticals Pvt Ltd

₹140/oral suspension

50% costlier

View all substitutes

Quick tips

Your child must complete the entire course of antibiotics. Stopping too soon may cause the bacteria to multiply again, become resistant, or cause another infection.
Your child must drink plenty of water if he/she develops diarrhea as a side effect.
Discontinue Linofit DS 100mg and inform the doctor immediately if your child develops a rash, itchy skin, swelling of face and mouth, or difficulty in breathing.
Only give Linofit DS 100mg to your child for their current infection. Never save medicine for future illnesses.

Fact Box

Chemical Class

Oxazolidinone derivative

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Action Class

Oxazolidinone

Interaction with drugs

Taking Linofit DS with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Amitriptyline

Brand(s): Triptam, Tryptomec, Amsha

Life-threatening

Amoxapine

Brand(s): Oxcap, A Pine, Axa

Life-threatening

Citalopram

Brand(s): Vocita, Celexa, Citlop

Life-threatening

Clomipramine

Brand(s): Imi-CI

Life-threatening

View all interactions

Patient concerns

My daughter is given tb medicine even though she is not infected taking these medicine will cause tb???

Dr. Rahul Yadav

Paediatrics

Hello, TB medicines are given only when there is indication of tuberculosis. They are for treating tuberculosis.

Scar on face due to bacterial infections

Dr. Atul Jain

Dermatology

Pic is not clear, plz visit for proper opinion

FAQs

Q. What if I give an excess of Linofit DS 100mg by mistake?

Overdose may cause unwanted side effects such as low blood count, nerve damage, or loss of vision. It may even cause a life-threatening complication called lactic acidosis which shows symptoms of abdominal pain, nausea, vomiting, and generalized weakness. Rush to your child’s doctor on an immediate basis if you notice any of these symptoms.

Q. My child is suffering from depression and is on antidepressant therapy. Is it safe to give Linofit DS 100mg along with these medicines?

No, it is not safe as it can lead to life-threatening syndrome known as serotonin syndrome which can be manifested as hypertension, increased heart rate, shaking of the body, seizures, and increased body temperature. Call your child’s doctor right away if these symptoms appear.

Q. What should I do if my child shows no improvement even after taking Linofit DS 100mg for the prescribed duration?

Ineffective treatment with Linofit DS 100mg could mean that the medicine is not able to act against the infection-causing bacteria. In such a case, visit your child’s doctor who may change the medicine and prescribe an antibiotic which has a stronger impact on the infection-causing bacteria. Since some of these antibiotics are given as intravenous injections, you may have to visit the doctor to give this medicine to your child.

Q. Can Linofit DS 100mg be given for a long duration?

Prolonged use of Linofit DS 100mg may result in fungal or bacterial superinfection, including <br>serious gastrointestinal infections due to inhibition of good bacteria of the gut. You must reach out to the doctor soon.

Q. Can other medicines be given at the same time as Linofit DS 100mg?

Linofit DS 100mg can sometimes interact with other medicines or substances. Tell your doctor about any other medicines your child is taking before starting Linofit DS 100mg. Also, check with your child’s doctor before giving any medicine to your child.

Q. What lab tests that are required for monitoring while my child is taking Linofit DS 100mg?

For children receiving Linofit DS 100mg for a longer duration, the doctor may ask for complete blood count, basic metabolic panel, liver function test, and routine eye and nerve function assessments.

Q. In which disease conditions should I avoid giving Linofit DS 100mg to my child?

Avoid giving Linofit DS 100mg if your child is suffering from conditions like diabetes mellitus (risk of low glucose), hypertension, hyperthyroidism, and seizure disorder. To ensure that this medicine is not given in such conditions, tell your child’s complete medical history to the doctor before giving Linofit DS 100mg to your child.

Q. What food items should my child avoid while taking Linofit DS 100mg?

Avoid giving tyramine-containing foods like old cheese, red meat, fava or broad bean pods, soy sauce, and other soybean condiments while your child is taking Linofit DS 100mg. Always recheck the freshness of food before giving it to your child as it is an important concern.

Q. Can I get my child vaccinated while on treatment with Linofit DS 100mg?

It is advised not to get your child vaccinated while they are on treatment with Linofit DS 100mg. Let your child recover from the ongoing illness and finish the course of the medicine As soon as a child is feeling better, even if he or she is on antibiotics, the vaccine can and should be given.

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Related lab tests

Complete Blood Count

Erythrocyte Sedimentation Rate

Mycobacterium Tuberculosis DNA PCR - Qualitative

Peripheral Smear Examination

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

MacDougall C, Chambers HF. Protein Synthesis Inhibitors and Miscellaneous Antibacterial Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1537-38.
Chambers HF, Deck DH. Tetracyclines, Macrolides, Clindamycin, Chloramphenicol, Streptogramins, & Oxazolidiones. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 804.
Linezolid [FDA Label]. New York, NY: Pharmacia & Upjohn Company; 2010. [Accessed 20 Jan. 2021] (online) Available from:
University of Michigan: C.S. Mott Children’s Hospital. Linezolid (oral/injection). [Accessed 21 Jan. 2020] (online) Available from:
Mayo Clinic. Drugs and Supplements: Linezolid (Oral Route). [Accessed 21 Jan. 2020] (online) Available from:

Marketer details

Name: Morepen Laboratories Ltd

Address: 409, Antriksh Bhawan, 22 Kasturba Gandhi Marg, New Delhi - 110 001

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.