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Lignorain 2% Injection

Written By Dr. Syeda Aafia, MBA, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 31 Mar 2026 | 02:31 PM (IST)
Lignorain 2% Injection is a local anesthetic. It is used during minor surgical procedures such as dental, oral, diagnostic, or other therapeutic procedures to anesthetize or numb the surgical area.
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Lignorain 2% Injection image
Lignorain 2% Injection image

Product introduction

Lignorain 2% Injection must be administered by healthcare professionals. It blocks the pain signals to reach the brain by temporarily numbing the surgical area and helps to perform a painless procedure.

This medicine is generally safe with little or no side effects. However, it may cause injection site reactions, such as pain, swelling, and redness, in some people. These are usually mild and short-lived. If the numbness or other side effects persist at the injection site, consult your doctor without any delay.

Before using Lignorain 2% Injection, it is very important to tell your doctor if you have any underlying heart disease or are taking medicines for heart rhythm problems. Ask your doctor for advice if you are pregnant or breastfeeding. Also, the medicine may cause dizziness. So avoid driving or operating heavy machinery while on medication.

Uses of Lignorain Injection

  • Local anesthesia (Numb tissues in a specific area)

Benefits of Lignorain Injection

Local anesthesia (Numb tissues in a specific area)
Lignorain 2% Injection is a local anesthetic. It makes your skin numb. It works by blocking nerve signals in your body. It is generally very safe, works quite quickly and will reduce discomfort that might be caused by invasive medical procedures such as surgery, needle punctures, or insertion of a catheter or breathing tube.

Side effects of Lignorain Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Lignorain
  • Injection site reactions (pain, swelling, redness)

How to use Lignorain Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Lignorain Injection works

Lignorain 2% Injection is a local anesthetic. It works by blocking the transmission of pain signals from the nerves to the brain. This helps to decrease the sensation of pain.

Quick tips

  • Lignorain 2% Injection is used to anesthetize or numb the surgical area during minor surgical procedures such as oral or dental.
  • It is given as an injection under the supervision of a doctor.
  • Minor injection site reactions (pain, swelling, redness) may occur for 1-2 minutes after injection. Notify your doctor if it persists for longer.
  • Use caution while doing anything that requires concentration as Lignorain 2% Injection can cause dizziness and sleepiness.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. 

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Lignorain 2% Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Lignorain 2% Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.
Driving

Driving

UNSAFE
Lignorain 2% Injection may cause side effects that could affect your ability to drive.
Kidney

Kidney

CAUTION
Lignorain 2% Injection should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Lignorain 2% Injection should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Lignorain with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Atenolol (Oral Route)

watch out for symptoms such as breathlessness, fatigue, drowsiness, sedation or faintness or vomiting and consult your doctor if you experience them. Lidocaine may increase the side effects of Atenolol.
Severe

Atenolol (Injection Route)

watch out for symptoms such as breathlessness, fatigue, drowsiness, sedation or faintness or vomiting and consult your doctor if you experience them. Lidocaine may increase the side effects of Atenolol.
Severe

Bisoprolol (Oral Route)

watch out for symptoms such as breathlessness, fatigue, drowsiness, sedation or faintness or vomiting and consult your doctor if you experience them. Bisoprolol may raise blood levels of Lidocaine.
Severe

Carvedilol (Oral Route)

watch out for symptoms such as breathlessness, fatigue, drowsiness, sedation or faintness or vomiting and consult your doctor if you experience them. Carvedilol may raise blood levels of Lidocaine.
Severe

Celiprolol (Oral Route)

watch out for symptoms such as breathlessness, fatigue, drowsiness, sedation or faintness or vomiting and consult your doctor if you experience them. Celiprolol may raise blood levels of Lidocaine.

Frequently asked questions

The anesthetic effect of Lignorain 2% Injection starts acting rapidly. However, it has a very short duration of action of 10-20 minutes after intravenous injection and 60-90 minutes after intramuscular action. The quantity of medicine reduces into half (into the blood-stream) within 1.5 to 2 hours of taking it.
No, Lignorain 2% Injection injection does not cause pain except when it is given as spinal anesthesia. Lignorain 2% Injection usually relieves pain in conditions like neuropathic pain and pain occurring after surgery.
Lignorain 2% Injection should not be given to patients who are allergic to it, have decreased blood volume (hypovolemia), or complete heart block. If the solution also contains adrenaline, it should not be injected into a vein or used in areas such as fingers, toes, ears, nose or penis, as the blood supply to these areas may not be sufficient.
No, abuse of Lignorain 2% Injection has not been observed yet. There are very rare reports of Lignorain 2% Injection injection causing any euphoric effect. However, Lignorain 2% Injection may cause some psychotic reactions such as fear from death, doom anxiety, and delirium. These are short-lasting and generally disappear after the effect of injection is over.

Fact Box

Chemical Class

M- xylenes

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

Action Class

Amide-Type Local Anesthetics

References

  1. Catterall WA, Mackie K. Local Anesthetics. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 572-73.
  2. Hume JR, Grant AO. Agents Used in Cardiac Arrhythmias. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 238-39.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 798-99.
  4. Lidocaine. Gloucester: Hameln Pharmaceuticals Ltd.; 2002 [revised 05 Apr. 2019]. [Accessed 05 Apr. 2019] (online) Available from:
  5. Lidocaine. Schaumburg, Illinois: APP Pharmaceuticals; 2010. [Accessed 05 Apr. 2019] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Rainbow Laboratories (india) Pvt Ltd
Address: W-124,GREATER KAILASH-II,NEW DELHI DL 000000 IN

Vendor Details

Country of origin: India
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