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Levopa 500mg Tablet

Levodopa (500mg)
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Levopa 500mg Tablet is used in the treatment of Parkinson's disease. This medicine helps to treat excessive shaking by slowing down the body movements.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 12 Mar 2026 | 11:07 AM (IST)
₹30.2 MRP ₹33.099% off 
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General Information

The content is shown in English
Levopa 500mg Tablet image
Levopa 500mg Tablet image

Product introduction

Levopa 500mg Tablet should be taken with food to avoid stomach upset. However, take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember it. You should never skip any doses and try to finish the full course of treatment even if you feel better.

Do not stop taking it suddenly without talking to your doctor as it can result in harmful effects. It is important to note that this drug may cause addiction in some individuals. It may be contraindicated if you have narrow-angle glaucoma or skin cancer, or have a history of fits.

This medicine may cause side effects like nausea, vomiting, muscle contraction, and movement disorder. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, so it is better to rise slowly if you have been sitting or lying down. It causes a sudden onset of dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. If you are undergoing any tests for urine glucose or urine ketones, it may cause the results of some tests to be wrong and even changes the color of urine, so consult your doctor before getting any such tests.

Uses of Levopa Tablet

Benefits of Levopa Tablet

Parkinson's disease
Parkinson’s disease is a progressive nervous system disorder that affects movement, causing symptoms such as tremors, stiffness, and slowed movements. Levopa 500mg Tablet helps replenish dopamine levels in the brain, improving muscle control and reducing symptoms like stiffness and tremors. This supports better mobility, coordination, and overall quality of life for people with Parkinson’s disease.

Side effects of Levopa Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Levopa
  • Nausea
  • Vomiting
  • Dizziness
  • Akathisia (inability to stay still)
  • Muscle contraction

How to use Levopa Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Levopa 500mg Tablet should be taken with or after food.

How Levopa Tablet works

Levopa 500mg Tablet works by being converted to dopamine, a chemical messenger that is needed to control the movement through transmission of signals in the brain.

Quick tips

  • Take it with or without food or as suggested by your doctor.
  • Avoid a high-protein diet (e.g. meat, eggs, and dairy products) while you are taking this medicine as it can reduce the amount of medication absorbed by your body.
  • Avoid vitamin supplements while taking Levopa 500mg Tablet as it may reduce the effectiveness of the medicine.
  • It may cause dizziness. Do not drive or do anything that requires mental focus until you know how this medicine affects you.
  • When you start the medication, get out of bed slowly, as the medication may cause lightheadedness or fainting.
  • Inform your doctor if you notice an urge to gamble, increased sexual urges, binge eating, or uncontrolled spending.
  • Do not stop taking the medication without talking to your doctor first.
  • Take it with or without food or as suggested by your doctor.
  • Avoid a high-protein diet (e.g. meat, eggs, and dairy products) while you are taking this medicine as it can reduce the amount of medication absorbed by your body.
  • Avoid vitamin supplements while taking Levopa 500mg Tablet as it may reduce the effectiveness of the medicine.
  • It may cause dizziness. Do not drive or do anything that requires mental focus until you know how this medicine affects you.
  • When you start the medication, get out of bed slowly, as the medication may cause lightheadedness or fainting.
  • Inform your doctor if you notice an urge to gamble, increased sexual urges, binge eating, or uncontrolled spending.
  • Do not stop taking the medication without talking to your doctor first.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Levopa 500mg Tablet.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Levopa 500mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CAUTION
Levopa 500mg Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

UNSAFE
Levopa 500mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Patients who have experienced somnolence and/or an episode of sudden sleep onset must refrain from driving or operating machines .
Kidney

Kidney

SAFE IF PRESCRIBED
Levopa 500mg Tablet is safe to use in patients with kidney disease. No dose adjustment is recommended.
Liver

Liver

SAFE IF PRESCRIBED
Levopa 500mg Tablet is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.

Interaction with drugs

Taking Levopa with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Selegiline (Oral Route)

Concurrent consumption of Levodopa and Selegiline should be avoided if you experience breathlessness, fatigue, drowsiness, sedation, faintness, vomiting, frequent falls, confusion, or dementia. Your doctor may adjust the doses of Levodopa to prevent its side effects.
Moderate

Moclobemide (Oral Route)

Talk to your doctor if you notice any unusual symptoms.
Moderate

Linezolid (Oral Route)

Watch out for symptoms such as tremors, fever, diarrhea or agitation and consult your doctor if you experience them. Your doctor may discontinue the medicines accordingly.
Moderate

Pramipexole (Oral Route)

Talk to your doctor if you notice any unusual symptoms.Doctor may monitor your liver function. Levodopa may reduce efficacy of Pramipexole.
Moderate

Linezolid (Injection Route)

Watch out for symptoms such as tremors, fever, diarrhea or agitation and consult your doctor if you experience them. Your doctor may discontinue the medicines accordingly.

Fact Box

Chemical Class

Tyrosine derivative

Habit Forming

No

Therapeutic Class

NEURO CNS

Action Class

Dopamine Precursors

References

  1. Standaert DG, Roberson ED. Treatment of Central Nervous System Degenerative Disorders. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 614-16.
  2. Aminoff MJ. Pharmacologic Management of Parkinsonism & Other Movement Disorders. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 470-74.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 791-93.
  4. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 20 Mar. 2019] (online) Available from:
  5. Carbidopa-Levodopa. Whitehouse Station, NJ: Merck $ Co., Inc.; 2008. [Accessed 15 Sept. 2020] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Wallace Pharmaceuticals Pvt Ltd
Address: Plot No. 100-105, Bethora Industrial Estate, Bethora, Ponda, Goa-403409 || 3rd Floor, Dempo Trade Centre Bldg., Patto Plaza, EDC Complex, Panaji 403001, Goa, India.

Vendor Details

Country of origin: India
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