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Leezole Gel is an antifungal medication. It is used in the treatment of fungal vaginal infections that may cause vaginal burning, itching, and abnormal discharge. It kills fungi by destroying the fungal cell membrane.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 09 Sep 2026 | 01:01 AM (IST)
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30 gm Vaginal gel
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Product expires after May, 2027

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General Information

Contains

Clotrimazole (2% w/w)

Marketer

Leeford Healthcare Ltd

Storage

Store below 30°C

Preservative

Benzyl Alcohol, Chlorocresol
The content is shown in English
Leezole Gel 1
Leezole Gel 2
Leezole Gel 3
Leezole Gel 4
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Leezole Gel 6
Leezole Gel 7
Leezole Gel 8
Leezole Gel 9

Product introduction

Leezole Gel is for external use only. You should use it in the dose and duration as advised by your doctor. It is best to use it at night for better results. The affected area should be clean before using the medicine. You must wash your hands thoroughly before and after applying this medicine. Do not stop using it until you have finished the complete course, even when you feel better.


Some of the common side effects include vaginal burning sensation and irritation. If the side effects bother you or do not go away, let your doctor know.


It is not likely that other medicines you take by mouth or injection will affect the way it works, but talk to your doctor before using it if you have used a similar medicine before and had an allergic reaction. This medicine should only be used if it is clearly needed during pregnancy.

Uses of Leezole Vaginal gel

Benefits of Leezole Vaginal gel

Treatment of Fungal infections of vagina
Leezole Gel helps treat fungal vaginal infections by stopping the growth of infection-causing fungi, particularly Candida species. It works directly at the site of infection to relieve symptoms such as itching, burning, irritation, abnormal discharge, and discomfort during urination or intercourse. It helps restore a normal vaginal environment and provides effective symptom relief when used as prescribed.

Side effects of Leezole Vaginal gel

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Leezole
  • Edema (swelling)
  • Erythema (skin redness)
  • Vaginal discharge
  • Itching
  • Stomach pain
  • Rash
  • Vulvovaginal discomfort

How to use Leezole Vaginal gel

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying

How Leezole Vaginal gel works

Leezole Gel is an antifungal medication. It kills and stops the growth of the fungi by destroying their cell membrane, thereby treating your infection.

All substitutes for Leezole Gel

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Use Leezole Gel exactly as prescribed and complete the full course, even if symptoms improve earlier.
  • Avoid sexual intercourse while you have vaginal thrush and during the course of treatment, as this may worsen irritation and delay healing.
  • This medicine may reduce the effectiveness of condoms and diaphragms made of latex. Avoid relying on these methods for contraception or protection during treatment and for up to 5 days after finishing the course.
  • Do not use tampons, intravaginal douches, spermicides, or other vaginal products while using this medicine, unless advised by your doctor.
  • Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding before using this medicine.
  • If symptoms do not improve within 7 days, worsen, or keep coming back, consult your doctor for further evaluation.

Safety advice

Alcohol

Alcohol

No interaction found/established
Pregnancy

Pregnancy

SAFE IF PRESCRIBED
Leezole Gel is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.
Driving

Driving

No interaction found/established
Kidney

Kidney

No interaction found/established
Liver

Liver

No interaction found/established
All

Interaction with drugs

Taking Leezole with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate

Codergocrine Mesylate (Oral Route)

Do not consume Codergocrine Mesylate with Clotrimazole. If concurrent use is essential, watch out for symptoms such as painful seizures and spasms, diarrhea, itching, headaches or nausea and consult your doctor if you experience them. Clotrimazole may raise blood levels of Codergocrine Mesylate.
Moderate

Sirolimus (Injection Route)

If concurrent use is essential, your doctor may monitor the levels and effects of Sirolimus on your kidneys and adjust the doses as per the observations. Clotrimazole may raise blood levels of Sirolimus.
Moderate

Sirolimus (Oral Route)

If concurrent use is essential, your doctor may monitor the levels and effects of Sirolimus on your kidneys and adjust the doses as per the observations. Clotrimazole may raise blood levels of Sirolimus.
Moderate

Tacrolimus (Oral Route)

If concurrent use is essential, your doctor may monitor your Tacrolimus levels and kidney function closely. They may adjust the doses as per the observations. Clotrimazole may raise blood levels of Tacrolimus.
Moderate

Calcitriol (Injection Route)

Your doctor may monitor your treatment and adjust the doses as per the observations. Clotrimazole may reduce the efficacy of Calcitriol.

Frequently asked questions

Leezole Gel is an antifungal medicine used to treat vaginal thrush (fungal infections of the vagina) caused by an overgrowth of Candida yeast. It helps relieve symptoms such as vaginal itching, burning, soreness, abnormal discharge, and irritation of the vulva (external thrush).
Symptoms such as itching, burning, and soreness usually begin to improve within a few days of starting treatment. However, it may take several days for symptoms to clear completely. If there is no improvement within 7 days, consult your doctor.
No. You should complete the full course of treatment (single-day or multi-day, as prescribed). Stopping treatment too early may allow the infection to return.
Yes. It is recommended to avoid vaginal intercourse while you have thrush and during treatment, as this can worsen irritation and delay healing.
Yes. Leezole Gel may reduce the effectiveness of latex condoms and diaphragms. Alternative contraception should be used during treatment and for up to 5 days after finishing the course.
No. Do not use tampons, intravaginal douches, spermicides, or other vaginal products while using Leezole Gel, unless advised by a doctor.
Routine treatment of partners is not usually required. However, if your partner has symptoms such as redness, itching, or irritation of the penis, medical advice should be sought.
If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before using Leezole Gel. Vaginal antifungals are commonly used in pregnancy, but medical guidance is important.

Fact Box

Chemical Class

Triphenyl compounds

Habit Forming

No

Therapeutic Class

ANTI INFECTIVES

Action Class

Fungal Ergosterol Synthesis Inhibitor

References

  1. Bennett JE. Antifungal Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. p. 1587.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 306-307.
100% genuine products
100% genuine products
Safe & secure payments
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No contact delivery
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Fully sanitized facilities
Fully sanitized facilities

User feedback

Fungal infections
100%
Poor
50%
Average
50%
With food
100%
Average
100%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Leeford Healthcare Ltd
Address: 203, Mangalam, Kulupwadi, Borivali (E), Mumbai-400066

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Leezole Gel. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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