Largan Syrup

Promethazine (5mg)

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Largan Syrup treats allergic and short-term common cold symptoms like runny nose, sneezing, watery eyes, skin rash, and itching in children. It also helps treat nausea, and vomiting caused after surgery or due to motion sickness (travel sickness).

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 12 Mar 2026 | 12:41 PM (IST)

₹20.3 MRP ₹22.510% off

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General Information

Contains

Promethazine (5mg)

Marketer

Southshourne Corporation India

Storage

Store below 30°C

The content is shown in English

Your child’s medicine at a glance

When given post-surgery, it makes your child sleepy and relaxed, helping the pain-relieving medicines work better. Give Largan Syrup to your child by mouth either before or after food. If your child develops stomach upset, give it preferably after food. The usual prescribed frequency is two to four times a day but may vary as per your child’s condition. For motion sickness, give Largan Syrup 30 to 60 minutes before travel whereas to prevent vomiting post-surgery, you may need to give it a night before the surgical procedure or just before the surgery and may need to continue it afterward as directed.

If your child vomits within 30 minutes of taking this medicine, give the same dose again. However, never repeat the dose if the next scheduled dose is near. Your child may start to feel better within a few days of regular dosing. However, you must continue giving the medicine to your child to finish the complete prescribed course as stopping it abruptly may worsen your child’s condition.

Some of the minor and temporary side effects that your child may experience while taking Largan Syrup include dry mouth, blurring of vision, drowsiness, dizziness, and constipation. These side effects usually subside once your child’s body adapts to the medicine. In case they persist or become bothersome for your child, consult your child’s doctor without any delay.

Inform the doctor if your child has any ongoing medicine regime or history of any allergy, heart problem, blood disorder, birth defects, airway obstruction, lung anomaly, skin disorder, liver impairment, and kidney malfunction. Awareness of your child’s medical history will help the doctor make dose alterations and better treatment planning.

Uses of Largan Syrup in children

Benefits of Largan Syrup for your child

Treatment of Nausea
Largan Syrup blocks the action of chemicals in the body that can make you feel or be sick. It is often used to prevent nausea and vomiting that may be caused due to some medicines or any other medical treatment. This medicine helps you recover more comfortably. The dose will depend on what you are being treated for but always take this medicine as it is prescribed.

Treatment of Allergic conditions
Largan Syrup is used to treat many different inflammatory and allergic conditions. It works by lowering your immune system’s response to these conditions and prevents the release of substances in the body that cause inflammation. It helps relieve symptoms such as swelling, pain, itching, and other allergic-type reactions. If you are not sure why you are being given this medicine, ask your doctor.

This medicine is given orally (by mouth). You should always take it as it has been prescribed for you. Do not stop taking it without your doctor’s advice. This can cause unpleasant withdrawal symptoms. Because this medicine weakens your immune system, you should avoid being near people who are ill or have infections.

Treatment of Motion sickness
Motion sickness is a condition caused due to motion during travel. You may experience spinning sensation (vertigo), nausea or vomiting as a result of this condition. Largan Syrup helps treat these symptoms effectively. Take it as prescribed by the doctor to get maximum benefit.

Side effects of Largan Syrup in children

Largan Syrup does not pose serious side effects and is well-tolerated by children. In case the side effects do occur, they’re likely to subside once the body adapts to the medicine. Consult your child’s doctor if these side effects persist or bother your child. The most common side effects include-

Common side effects of Largan

Constipation
Slow heart rate
Hypotension (low blood pressure)
Tremors

How can I give Largan Syrup to my child?

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Largan Syrup may be taken with or without food.

How Largan Syrup works

Largan Syrup is an antiallergic medication. When the body is exposed to an allergen (pollen, animal dander, house dust, etc.), it releases a chemical called histamine. This chemical causes watery eyes, runny or blocked nose, sneezing, skin rashes, itching, etc. Largan Syrup also works directly on several areas of the brain to prevent nausea and vomiting and help you feel more relaxed.

Quick tips

Stop taking it at least three days before taking an allergy test as it can affect the test results.
Largan Syrup may make your child feel sleepy. Ensure your child takes extra care when taking part in physical activities.
Avoid using Largan Syrup in children less than 2 years of age as it can cause fatal respiratory distress.
Do not give Largan Syrup if your child has liver disease. Tell the complete medical history of your child to the doctor.
Stop Largan Syrup and immediately report to the doctor if your child develops an itchy rash, facial swelling, or breathing difficulties.
Avoid driving or operating dangerous machinery as it may decrease alertness.
Avoid consuming alcohol when taking the Largan Syrup, as it may cause excessive sleepiness or drowsiness.

Safety advice

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of Largan Syrup in patients with kidney disease. Please consult your doctor.
Discuss with your child’s doctor thoroughly before giving Largan Syrup to your child in case of severe kidney disease

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Largan Syrup in patients with liver disease.
Use of Largan Syrup is not recommended in children with severe liver disease and active liver disease.

Interaction with drugs

Taking Largan with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Tranylcypromine (Oral Route)

Do not consume Tranylcypromine with Promethazine. If Tranylcypromine is essential, ensure a gap of at least 2 weeks after discontinuing Promethazine. Please consult your doctor.

Moderate

Trihexyphenidyl (Injection Route)

Talk to your doctor if you notice any unusual symptoms.

Moderate

Clozapine (Oral Route)

Watch out for symptoms such as dry mouth, increased heart rate, urination difficulties, constipation, loss of appetite or nausea and consult your doctor if you experience them.

Moderate

Trihexyphenidyl (Oral Route)

Talk to your doctor if you notice any unusual symptoms.

Moderate

Lorazepam (Oral Route)

Do not drive or do anything requiring concentration or alertness until you know how the medicines affect you.

Frequently asked questions

My child is 1 year old. Is it safe to give Largan Syrup to my child who is suffering from a common cold?

Largan Syrup should not be given to children less than 2 years of age as it may cause fatal respiratory depression wherein your child’s breathing may stop completely.

What if I give an overdose of Largan Syrup by mistake?

Always stick to the prescribed dose. Prolonged or excess intake of Largan Syrup can put your child at risk of developing serious side effects like bradycardia, decreased blood pressure, confusion, delirium, disorientation, dizziness, drowsiness, and hallucinations. Rush to your child’s doctor immediately if you feel you have given excess Largan Syrup to your child. To pour out the right dose, use the calibrated cup provided with the medicine by the manufacturer. Do not use a kitchen teaspoon as it will not give the correct estimate.

When will my child’s condition improve after taking Largan Syrup?

Largan Syrup usually starts working within 30 to 60 minutes of intake and shows its peak effect within 3 to 4 hours. Your child may start to feel better after a few doses. In case the symptoms persist longer, consult your child’s doctor immediately.

Can other medicines be given at the same time as Largan Syrup?

Largan Syrup can sometimes interact with other medicines or substances. Tell your doctor about any other medicines your child is taking before starting Largan Syrup. Also, check with your child’s doctor before giving any medicine to your child.

Can Largan Syrup make my child sleepy?

Largan Syrup may cause mild drowsiness, making your child feel sleepy. So, be cautious and never give this medicine if your child is suffering from a sleep disorder as this medicine can mask the symptoms of underlying sleep disorders like insomnia. It is always best to consult your child’s doctor before giving this medicine to your child.

Where should I keep Largan Syrup?

Keep Largan Syrup out of the reach and sight of children to avoid any accidental intake. Keep it at room temperature, in a dry place, away from direct heat and light.

When should I call my child’s doctor right away?

You should call the doctor without any delay if your child starts to develop side effects such as irregular heartbeat, vision problem, muscle spasm, irregular bodily movements, sudden weakness, and inability to empty the bladder completely (urinary retention).

My child is an athlete and has to participate in a sports event in the school. Can I give Largan Syrup before his performance?

This medicine may cause CNS depression in which the normal nerve functioning slows down. So, avoid giving Largan Syrup to your child if he/she is scheduled to perform tasks that require mental alertness.

Fact Box

Chemical Class

Phenothiazines

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Action Class

First-Generation H1 Antihistamines

Related lab tests

Absolute Eosinophil Count

Peripheral Smear Examination

Total IgE

References

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Southshourne Corporation India
Address: Plot No 931, Gidc Estate, Makarpura Industrial Estate, Vadodara - 390010

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Largan Syrup

Save more with additional offers

General Information

Contains

Marketer

Storage

Your child’s medicine at a glance

Uses of Largan Syrup in children

Benefits of Largan Syrup for your child

Side effects of Largan Syrup in children

How can I give Largan Syrup to my child?

How Largan Syrup works

Quick tips

Safety advice

Kidney

Liver

Interaction with drugs

Tranylcypromine (Oral Route)

Trihexyphenidyl (Injection Route)

Clozapine (Oral Route)

Trihexyphenidyl (Oral Route)

Lorazepam (Oral Route)

Frequently asked questions

My child is 1 year old. Is it safe to give Largan Syrup to my child who is suffering from a common cold?

What if I give an overdose of Largan Syrup by mistake?

When will my child’s condition improve after taking Largan Syrup?

Can other medicines be given at the same time as Largan Syrup?

Can Largan Syrup make my child sleepy?

Where should I keep Largan Syrup?

When should I call my child’s doctor right away?

My child is an athlete and has to participate in a sports event in the school. Can I give Largan Syrup before his performance?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Absolute Eosinophil Count

Peripheral Smear Examination

Total IgE

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests