Irnotel 100mg Injection
View available alternative with same salt composition
Product introduction
Irnotel 100mg Injection is used in the treatment of cancer of colon and rectum. It shows its working by stopping or slowing down the growth of cancer cells.
Irnotel 100mg Injection is given as an IV infusion into vein by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include fatigue, nausea, vomiting, weakness, and hair loss. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Inform your doctor if you notice fever, sore throat, and continuous episodes of diarrhea. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses of Irnotel Injection
Benefits of Irnotel Injection
In Cancer of colon and rectum
Cancer of the colon and rectum, also known as colorectal cancer (CRC) or bowel cancer, is the development of cancer from two parts of the large intestine, namely, the colon or rectum. In this type of cancer, the person may notice symptoms such as blood in the stool, a change in bowel movements, weight loss, and fatigue. Irnotel 100mg Injection treats and also lowers the risk of developing further cancerous growths (polyps) and bowel cancer. It kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective, yet very toxic medicine and you should discuss the risks and benefits with your doctor. Avoid drinking alcohol or smoking while having this treatment and drink plenty of water to stay hydrated.
Side effects of Irnotel Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Irnotel
- Fatigue
- Nausea
- Vomiting
- Weakness
- Hair loss
- Fever
- Anemia (low number of red blood cells)
- Diarrhea
- Decreased white blood cell count (neutrophils)
- Decreased appetite
- Mucosal inflammation
How to use Irnotel Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Irnotel Injection works
Irnotel 100mg Injection is an anti-cancer medication. It works by suppressing the activity of an enzyme (topoisomerase I) involved in DNA multiplication of the cancer cells. This slows the growth of cancer cells and eventually kills them.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Irnotel 100mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Irnotel 100mg Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding
UNSAFE
Irnotel 100mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Irnotel 100mg Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Irnotel 100mg Injection is probably safe to use in patients with kidney disease. Limited data suggest dose adjustment may not be needed.
Use of this medicine is not recommended for patients on dialysis.
Use of this medicine is not recommended for patients on dialysis.
Liver
CONSULT YOUR DOCTOR
There is limited data available on the use of Irnotel 100mg Injection in patients with liver disease.
What if you forget to take Irnotel Injection?
If you miss a dose of Irnotel 100mg Injection, please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Irnotel 100mg Injection
₹819/Injection
Irnocel 100mg Injection
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₹3839.06/injection
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Irinot 100mg Injection
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₹3843.75/injection
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Inotad 100mg Injection
Adley Formulations
₹1386/injection
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Stritosar 100mg Injection
Mylan Pharmaceuticals Pvt Ltd - A Viatris Company
₹3752.81/injection
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Quick tips
- Irnotel 100mg Injection is used in combination with other medicines for the treatment of metastatic cancer of the colon and rectum.
- It is given via a drip into a vein (intravenous infusion).
- It may cause dizziness and visual disturbances. Do not drive or do anything that requires mental focus until you know how it affects you.
- Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
- Your doctor may get regular blood tests done to monitor your blood cells, kidney and liver function during treatment with this medicine.
- Inform your doctor immediately if you notice any signs of infection such as fever, sore throat or rash.
- Inform your doctor if you notice passage of blood in stools or experience dizziness or faintness, continuous episodes of nausea, vomiting, diarrhea or fever.
Fact Box
Chemical Class
Camptothecins
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Topoisomerase Inhibitors
Interaction with drugs
Taking Irnotel with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Do not consume Irinotecan with Atazanavir. If Irinotecan is essential, ensure a gap of at least 1 week after discontinuing Atazanavir. Please consult your doctor. Atazanavir may ra
Do not consume Irinotecan with Carbamazepine. If concurrent use is essential, please consult your doctor. Carbamazepine may fasten the elimination of Irinotecan and its active form
Do not consume Irinotecan with Phenobarbitone. If concurrent use is essential, please consult your doctor. Phenobarbitone may fasten the elimination of Irinotecan and its active fo
Do not consume Irinotecan with Phenobarbitone. If concurrent use is essential, please consult your doctor. Phenobarbitone may fasten the elimination of Irinotecan and its active fo
Do not consume Irinotecan with Clarithromycin. If Irinotecan is essential, ensure a gap of at least 1 week after discontinuing Clarithromycin. Please consult your doctor. Clarithro
Patient concerns
FAQs
What is Irnotel 100mg Injection used for?
Irnotel 100mg Injection is used to treat colon and rectal cancer, especially when the cancer has spread to other parts of the body. It is often used alone or in combination with other chemotherapy medicines.
How is Irnotel 100mg Injection given?
Irnotel 100mg Injection is administered as an intravenous (IV) infusion by a doctor, usually over 90 minutes. It is not taken at home, and the dose depends on your body size, health condition, and treatment plan.
Can Irnotel 100mg Injection cause serious side effects?
Yes. Irnotel 100mg Injection can cause serious side effects, such as severe diarrhea, dangerously low white blood cell counts, dehydration, infections, and allergic reactions. Prompt medical attention is important if you experience a high fever, chills, or persistent diarrhea.
What should I know about diarrhea caused by Irnotel 100mg Injection?
Irnotel 100mg Injection can cause two types of diarrhea: early-onset and late-onset. Early diarrhea may occur within 24 hours and may include sweating or stomach cramps. Late diarrhea occurs more than 24 hours after treatment and can be severe. You may be prescribed anti-diarrhea medication to manage these symptoms.
Who should not receive Irnotel 100mg Injection?
Individuals should not take Irnotel 100mg Injection if they are allergic to it or have had severe side effects from it previously. It may not be suitable for individuals with certain liver or bowel conditions, or those who are severely dehydrated.
Can Irnotel 100mg Injection affect my ability to fight infections?
Yes. Irnotel 100mg Injection can lower the number of white blood cells in your body, making it harder to fight infections. It is important to avoid close contact with people who are sick and report signs of infection, such as fever or sore throat, immediately.
What precautions should I take while on Irnotel 100mg Injection treatment?
While on Irnotel 100mg Injection treatment, you should stay well hydrated, follow all instructions regarding medications to manage side effects, and report any symptoms of infection, breathing problems, or unusual bleeding. Avoid grapefruit juice, as it may interfere with the medicine’s effect.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 951.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 736-37.
- Irinotecan hydrochloride trihydrate. Sandwich, Kent: Pfizer Limited; 1995 [revised May 2018]. Accessed 26 Jan. 2019] (online) Available from:
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Irinotecan. [Updated 2018 Dec 3]. [Accessed 18 Feb. 2020] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 26 Mar. 2019] (online) Available from:
Marketer details
Name: Fresenius Kabi India Pvt Ltd
Address: Fresenius Kabi AG , Else-Kröner-Straße 1 , 61352 Bad Homburg , Germany
Country of origin: India
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₹819
Inclusive of all taxes
MRP₹889 8% OFF
1.0 Injection in 1 vial
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