Irnocel 100mg Injection

Irinotecan (100mg)

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Irnocel 100mg Injection is used in the treatment of cancer of colon and rectum. It shows its working by stopping or slowing down the growth of cancer cells.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 14 Apr 2026 | 04:21 PM (IST)

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General Information

Contains

Irinotecan (100mg)

Marketer

Celon Laboratories Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Irnocel 100mg Injection is given as an IV infusion into vein by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include fatigue, nausea, vomiting, weakness, and hair loss. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Inform your doctor if you notice fever, sore throat, and continuous episodes of diarrhea. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Irnocel Injection

Cancer of colon and rectum

Benefits of Irnocel Injection

Cancer of colon and rectum
Cancer of the colon and rectum, also known as colorectal cancer (CRC) or bowel cancer, is the development of cancer from two parts of the large intestine, namely, the colon or rectum. In this type of cancer, the person may notice symptoms such as blood in the stool, a change in bowel movements, weight loss, and fatigue. Irnocel 100mg Injection treats and also lowers the risk of developing further cancerous growths (polyps) and bowel cancer. It kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective, yet very toxic medicine and you should discuss the risks and benefits with your doctor. Avoid drinking alcohol or smoking while having this treatment and drink plenty of water to stay hydrated.

Side effects of Irnocel Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Irnocel

Fatigue
Nausea
Vomiting
Weakness
Hair loss
Fever
Anemia (low number of red blood cells)
Diarrhea
Decreased white blood cell count (neutrophils)
Decreased appetite
Mucosal inflammation

How to use Irnocel Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Irnocel Injection works

Irnocel 100mg Injection is an anti-cancer medication. It works by suppressing the activity of an enzyme (topoisomerase I) involved in DNA multiplication of the cancer cells. This slows the growth of cancer cells and eventually kills them.

All substitutes for Irnocel 100mg Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Irnocel 100mg Injection is used in combination with other medicines for the treatment of metastatic cancer of the colon and rectum.
It is given via a drip into a vein (intravenous infusion).
It may cause dizziness and visual disturbances. Do not drive or do anything that requires mental focus until you know how it affects you.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
Your doctor may get regular blood tests done to monitor your blood cells, kidney and liver function during treatment with this medicine.
Inform your doctor immediately if you notice any signs of infection such as fever, sore throat or rash.
Inform your doctor if you notice passage of blood in stools or experience dizziness or faintness, continuous episodes of nausea, vomiting, diarrhea or fever.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Irnocel 100mg Injection. Please consult your doctor.

Pregnancy

UNSAFE

Irnocel 100mg Injection is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

UNSAFE

Irnocel 100mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Irnocel 100mg Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Irnocel 100mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Use of this medicine is not recommended for patients on dialysis.

Liver

CAUTION

Irnocel 100mg Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Irnocel with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Phenobarbitone (Oral Route)

Do not consume Irinotecan with Phenobarbitone. If concurrent use is essential, please consult your doctor. Phenobarbitone may fasten the elimination of Irinotecan and its active form.

Severe

Phenobarbitone (Injection Route)

Do not consume Irinotecan with Phenobarbitone. If concurrent use is essential, please consult your doctor. Phenobarbitone may fasten the elimination of Irinotecan and its active form.

Severe

Atazanavir (Oral Route)

Do not consume Irinotecan with Atazanavir. If Irinotecan is essential, ensure a gap of at least 1 week after discontinuing Atazanavir. Please consult your doctor. Atazanavir may raise blood levels of Irinotecan.

Severe

Carbamazepine (Oral Route)

Do not consume Irinotecan with Carbamazepine. If concurrent use is essential, please consult your doctor. Carbamazepine may fasten the elimination of Irinotecan and its active form.

Severe

Clarithromycin (Oral Route)

Do not consume Irinotecan with Clarithromycin. If Irinotecan is essential, ensure a gap of at least 1 week after discontinuing Clarithromycin. Please consult your doctor. Clarithromycin may raise blood levels of the active form of Irinotecan.

Frequently asked questions

What is Irnocel 100mg Injection used for?

Irnocel 100mg Injection is used to treat colon and rectal cancer, especially when the cancer has spread to other parts of the body. It is often used alone or in combination with other chemotherapy medicines.

How is Irnocel 100mg Injection given?

Irnocel 100mg Injection is administered as an intravenous (IV) infusion by a doctor, usually over 90 minutes. It is not taken at home, and the dose depends on your body size, health condition, and treatment plan.

Can Irnocel 100mg Injection cause serious side effects?

Yes. Irnocel 100mg Injection can cause serious side effects, such as severe diarrhea, dangerously low white blood cell counts, dehydration, infections, and allergic reactions. Prompt medical attention is important if you experience a high fever, chills, or persistent diarrhea.

What should I know about diarrhea caused by Irnocel 100mg Injection?

Irnocel 100mg Injection can cause two types of diarrhea: early-onset and late-onset. Early diarrhea may occur within 24 hours and may include sweating or stomach cramps. Late diarrhea occurs more than 24 hours after treatment and can be severe. You may be prescribed anti-diarrhea medication to manage these symptoms.

Who should not receive Irnocel 100mg Injection?

Individuals should not take Irnocel 100mg Injection if they are allergic to it or have had severe side effects from it previously. It may not be suitable for individuals with certain liver or bowel conditions, or those who are severely dehydrated.

Can Irnocel 100mg Injection affect my ability to fight infections?

Yes. Irnocel 100mg Injection can lower the number of white blood cells in your body, making it harder to fight infections. It is important to avoid close contact with people who are sick and report signs of infection, such as fever or sore throat, immediately.

What precautions should I take while on Irnocel 100mg Injection treatment?

While on Irnocel 100mg Injection treatment, you should stay well hydrated, follow all instructions regarding medications to manage side effects, and report any symptoms of infection, breathing problems, or unusual bleeding. Avoid grapefruit juice, as it may interfere with the medicine’s effect.

Fact Box

Chemical Class

Camptothecins

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Topoisomerase Inhibitors

Related lab tests

Carcino Embryonic Antigen

References

Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 951.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 736-37.
Irinotecan hydrochloride trihydrate. Sandwich, Kent: Pfizer Limited; 1995 [revised May 2018]. Accessed 26 Jan. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Irinotecan. [Updated 2018 Dec 3]. [Accessed 18 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 26 Mar. 2019] (online) Available from:

User feedback

What are you using Irnocel Injection for?

Cancer of colon and rectum

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Others

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How much was the improvement?

Poor

100%

What were the side-effects while using Irnocel 100mg Injection?

Hair loss

100%

How do you take Irnocel Injection?

With food

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Please rate Irnocel 100mg Injection on price

Not Expensive

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Celon Laboratories Ltd
Address: Plot No 264, Patrika Nagar Madhapur, Hitech City Hyderabad, Telangana India - 500081

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Irnocel 100mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Irnocel 100mg Injection

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Irnocel Injection

Benefits of Irnocel Injection

Side effects of Irnocel Injection

How to use Irnocel Injection

How Irnocel Injection works

All substitutes for Irnocel 100mg Injection

Irinot 100mg Injection

Inotad 100mg Injection

Stritosar 100mg Injection

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Phenobarbitone (Oral Route)

Phenobarbitone (Injection Route)

Atazanavir (Oral Route)

Carbamazepine (Oral Route)

Clarithromycin (Oral Route)

Frequently asked questions

What is Irnocel 100mg Injection used for?

How is Irnocel 100mg Injection given?

Can Irnocel 100mg Injection cause serious side effects?

What should I know about diarrhea caused by Irnocel 100mg Injection?

Who should not receive Irnocel 100mg Injection?

Can Irnocel 100mg Injection affect my ability to fight infections?

What precautions should I take while on Irnocel 100mg Injection treatment?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Carcino Embryonic Antigen

References

User feedback

What are you using Irnocel Injection for?

How much was the improvement?

What were the side-effects while using Irnocel 100mg Injection?

How do you take Irnocel Injection?

Please rate Irnocel 100mg Injection on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests