Integrilin Injection is a blood thinner which prevents formation of harmful blood clots. It is used in the treatment of a heart attack and also prevents the clotting of blood in the heart during an angioplasty (procedure to improve blood flow to the heart).
Integrilin Injection is administered under the supervision of a doctor. Your doctor will decide the dose and duration of the medicine for you. You should continue all your other medicines that are advised by the doctor for your long-term treatment even after this injection.
Use of this medicine may cause low blood platelets and increase your risk of bleeding. Let your doctor know immediately if you see pinpoint rash or blood in your vomits, urine, or stool. It may also cause low blood pressure as a side effect. Your doctor will explain the benefits and risks associated with this medicine before it is administered.
This medicine is used with caution for some people. Before taking it, you must inform the doctor if you are suffering from any bleeding disorder, kidney or liver disease. Also, let your doctor know if you are pregnant or breastfeeding and about all the other medications that you are taking regularly.
It prevents blood from clotting inside the veins and arteries. This helps the blood flow freely around your body thereby preventing a heart attack or stroke (or deep vein thrombosis or pulmonary embolism). Follow your doctor’s instructions carefully and make appropriate lifestyle changes (such as eating healthy and staying active) to maximize the effectiveness of this medicine.
In Prevention of Blood clots
Integrilin Injection prevents new blood clots from forming and prevents the existing ones from getting bigger. It works by blocking a substance in the body which is involved in blood clotting. Thus it helps your blood flow smoothly throughout the body. This can help reduce damage caused by clots in your lungs (pulmonary embolism), brain (stroke), heart (heart attack) or other blood vessels (thrombosis).
Side effects of Integrilin Infusion
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Integrilin
Bleeding
Decreased blood pressure
How to use Integrilin Infusion
Your doctor or nurse will give you this medicine. Kindly do not self-administer.
How Integrilin Infusion works
Integrilin Injection is an antiplatelet medication. It works by preventing the platelets from sticking together, thereby decreasing the formation of harmful blood clots.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Integrilin Injection. Please consult your doctor.
Pregnancy
SAFE IF PRESCRIBED
Integrilin Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
CAUTION
Integrilin Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Driving
NOT RELEVANT
Not relevant, as Integrilin Injection is intended for use in hospitalised patients.
Kidney
CAUTION
Integrilin Injection should be used with caution in patients with kidney disease. Dose adjustment of Integrilin Injection may be needed. Please consult your doctor. Use of Integrilin Injection is not recommended in patients with severe kidney disease.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Integrilin Injection in patients with liver disease. Please consult your doctor. Use of Integrilin Injection is not recommended in patients with severe liver disease.
What if you forget to take Integrilin Infusion?
If you miss a dose of Integrilin Injection, please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Do not consume Apixaban with Eptifibatide. If concurrent use is essential, watch out for bleeding and consult your doctor immediately.
Concurrent use may increase the risk of blee... More
If concurrent use is essential, watch out for bleeding and consult your doctor immediately. Your doctor may change the treatment accordingly.
Concurrent use may increase the risk ... More
He is heart patients and has undergone angioplasty but still it pains near sternum bone At the time of attack he was suffering the same problem but after angioplasty too problem exist He has large sternum bone from birth
Dr. Nabajit Talukdar
Cardiology
That probably not anginaYou can have diathermy to relieve that
What are the health problems that one can get if the one keeps on taking a chronic stress and depression over a prolonged period of time. Seing that im experiencing some symtoms like chronic head ache, nausea, heart pain, gastrointiatinal bleeding, urine in the blood, sleep deprivation, weight loss due to exyreme thinking. Pls advise me in this connection
My father in law is being admitted in hospital due to blood clot in brain. His right leg and arm seems to be paralysed. Doctors in the hospital not briefing us on the problem exactly. Need your second opinion. His age is 67. Having Smoking habit.
Can the use of Integrilin Injection increase the risk of bleeding?
Yes, Integrilin Injection increases the risk of bleeding. Always be careful while doing activities that may cause an injury or bleeding. Tell your doctor immediately if you notice any abnormal bruising or bleeding.
What medicines should I avoid while taking Integrilin Injection?
Integrilin Injection can interact with several medicines. Do not take any medicine without talking to your doctor.
When will I feel better after taking Integrilin Injection?
Integrilin Injection reduces your risk of developing blood clots in the blood vessels of your leg, lungs, heart and brain. You may not feel any difference after taking Integrilin Injection. However, keep taking this medicine as prescribed by your doctor because you will still be getting its full benefits.
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
Weitz JI. Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 871.
Fox KA, White HD, Gersh BJ, et al. Antithrombotic Agents: Platelete Inhibitors, Acute Anticoagulants, Fibrinolytics, and Chronic Anticoagulants. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 355-56.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 485-46.
Eptifibatide. Ferentino, Italy: Patheon Italia S.p.A.; 1998 [revised Mar. 2013]. [Accessed 18 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). Eptifibatide. [Accessed 18 Mar. 2019] (online) Available from:
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