Innomune Tablet

Written By Dr. Lipika Khurana, PGDHHM, BDS

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 14 Apr 2026 | 04:20 PM (IST)

Innomune Tablet belongs to a group of medicines called immunosuppressants. It is used with other medicines to prevent your body from rejecting an organ (such as a kidney, heart, or liver) after a transplant. It is also used in the treatment of rheumatoid arthritis.

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Innomune Tablet

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Azathioprine (50mg)

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General Information

Contains

Azathioprine (50mg)

Marketer

Cipla Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

The dose of Innomune Tablet and how often you need to take it will depend on whether you have had a transplant or are being treated for rheumatoid arthritis. Follow your doctor’s instructions on this. You can take it with or without food. Take the medicine regularly to get the most benefit and keep taking it even if you feel well. If you stop taking it, the risk of organ rejection may increase, and if you're using it for rheumatoid arthritis, your symptoms may not improve.

The most common side effects of Innomune Tablet are nausea and reduction of white blood cells and bone marrow function. Because it suppresses your immune system, you may catch infections easily. There is also an increased risk of developing some cancers for this reason. You should ask your doctor about side effects that may require urgent medical attention.

Innomune Tablet can cause birth defects and miscarriages, so do not take it if you are pregnant, planning to become pregnant, or breastfeeding. You should talk to your doctor before taking this medicine if you have any signs of infection or any unexpected bruising or bleeding. Let your doctor also know what other medications you are taking, as some may interact with this medicine and affect the way it works. You will have regular tests to check for any changes in the number of your blood cells.

Uses of Innomune Tablet

Benefits of Innomune Tablet

Treatment of Rheumatoid arthritis
Innomune Tablet works by blocking the action of some chemicals which cause inflammation. It can help reduce pain, stiffness, and swelling in your joints and slow down the progression of bone and joint damage. This will help you do normal daily activities more easily and thus improve your quality of life. This medicine should be taken at the same time each day to get maximum benefits. Keep taking it even if you feel well because it is preventing future harm as well as improving your symptoms.

Prevention of organ rejection in transplant patients
Innomune Tablet is an immunosuppressive agent that lowers your immune response and reduces the chance of your body attacking the transplanted organ. Organ rejection happens when your immune system treats the new organ as an invader and attacks it. This medicine may be used in combination with other medicines to suppress the immune system and help your body accept the new organ.

Side effects of Innomune Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Innomune

Viral infection
Fungal infection
Bacterial infection
Decreased white blood cell count
Bone marrow disorder
Increased bleeding tendency
Nausea

How to use Innomune Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Innomune Tablet may be taken with or without food.

How Innomune Tablet works

Innomune Tablet is an immunosuppressant. It reduces the action of the body's defense system (the immune system) and prevents rejection of the transplanted organ. It also blocks the action of certain chemical messengers that are responsible for inflammation, swelling, and redness associated with certain joint diseases.

All substitutes for Innomune Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

You may have to take additional medications along with Innomune Tablet for better relief of symptoms.
Avoid contact with people who have a cold, flu, or other contagious illness. Notify your doctor if you have any signs of infection, such as a fever or sore throat.
Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.

Safety advice

Alcohol

CAUTION

Alcohol should be used with caution while taking Innomune Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Innomune Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

UNSAFE

Innomune Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

SAFE

Innomune Tablet does not usually affect your ability to drive.

Kidney

CAUTION

Innomune Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Use of Innomune Tablet is not recommended in patients with serious kidney disease.

Liver

CAUTION

Innomune Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Use of Innomune Tablet is not recommended in patients with severe liver disease. Regular monitoring of liver function tests is advisable while you are taking this medicine.

Interaction with drugs

Taking Innomune with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Pegfilgrastim (Injection Route)

Do not consume Azathioprine from 14 days before until 24 days after taking Pegfilgrastim. Please consult your doctor.

Life-threatening

Sargramostim (Injection Route)

Do not consume Azathioprine from 1 day before until 1 day after taking Sargramostim. Please consult your doctor.

Life-threatening

Lenograstim (Injection Route)

Do not consume Lenograstim from 24 hours before until 24 hours after undergoing cytotoxic chemotherapy.

Severe

Leflunomide (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.

Severe

Filgrastim (Injection Route)

Do not consume Filgrastim from 24 hours before and until 24 hours after taking Azathioprine.

Frequently asked questions

What is Innomune Tablet prescribed for? How does it work?

Innomune Tablet is an immunosuppressant, which means that it acts by suppressing the immune defense system of the body. Your immune defense system helps to protect you against infections. However, sometimes your immune defense system can become overactive and can cause illness. Innomune Tablet is used in combination with other medicines to treat the conditions caused by this abnormal activity of the immune system. It is used to prevent the rejection of transplanted organs, like the kidney, heart, or liver. It is also used to treat rheumatoid arthritis.

How long do I need to take Innomune Tablet?

The duration varies from person to person, as it is prescribed depending on the patient’s medical condition.

Is breastfeeding safe during Innomune Tablet treatment?

No, breastfeeding should be avoided while on Innomune Tablet, since it may harm the baby and cause serious side effects.

I have just started taking Innomune Tablet. What are the long-term side effects? Is there anything I should be looking out for?

Being an immunosuppressant, Innomune Tablet can increase the chances of severe infections and decrease blood cell counts, and malignancy. You should inform your doctor immediately if you notice any infection or fever, unexpected bruising or bleeding, black tarry stools, or blood in the urine or stools. Let your doctor know if you notice any new skin sore or lump, new marks on the skin, or any change in the marks that were previously present.

Do I need any special tests while I am on Innomune Tablet?

Innomune Tablet reduces the production of white blood cells, making you more vulnerable to infections, and can sometimes affect the liver. These side effects can be monitored by regular blood tests. Therefore, during the first 8 weeks of the treatment, your doctor may recommend weekly blood tests to monitor complete blood counts, including platelet counts. The frequency can later be reduced to monthly or at least once every 3 months.

Can Innomune Tablet cause cancer?

Innomune Tablet may increase the chance of developing certain cancers like skin cancer, cancer of the lymph system (lymphoma), cancer of soft tissues (sarcomas), and cervical cancer. To prevent the risk of skin cancer, avoid prolonged exposure to sunlight and wear protective clothing, sunglasses, and sunscreen. Tell your doctor immediately if you notice any changes in your skin or any lumps or masses anywhere on your body.

Fact Box

Chemical Class

Diarylthioethers

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Immunosuppressant- Purine analogs

Related lab tests

Rheumatoid Factor - Agglutination

Rheumatoid Factor - Turbidometry

Rheumatoid Factor IgG Antibody

References

Krensky AM, Bennett WM, Vincenti F. Immunosuppressants, Tolerogens, and Immunostimulants. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1013-14.
Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 629-30.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 113-15.
Azathioprine [Prescribing Information]. San Diego, California: Prometheus Laboratories Inc.; 2014. [Accessed 06 Apr. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 03 Apr. 2019] (online) Available from:
Azathioprine [Product Information]. Parsippany, NJ: Ascend Laboratories, LLC; 2021. [Accessed 09 Jun, 2023] (online) Available from:
Mohammadi O, Kassim TA. Azathioprine. [Updated 2023 May 1]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023. [Accessed 09 Jun, 2023] (online) Available from:
Azathioprine [EMC Label]. Luton, UK: Tillomed Laboratories Ltd.; 2025. [Accessed 25 Feb. 2025] (online) Available from:

User feedback

What are you using Innomune Tablet for?

Prevention of organ rejection in transplant patients

67%

Others

33%

How much was the improvement?

Excellent

100%

What were the side-effects while using Innomune Tablet?

Loss of appetite

25%

Increased bleeding tendency

25%

Nausea

25%

Infection

25%

How do you take Innomune Tablet?

With food

100%

Please rate Innomune Tablet on price

Expensive

100%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Cipla Ltd
Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Innomune Tablet

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Innomune Tablet

Benefits of Innomune Tablet

Side effects of Innomune Tablet

How to use Innomune Tablet

How Innomune Tablet works

All substitutes for Innomune Tablet

AZR Tablet

Aretha Tablet

aZApure Tablet

Zymurine Tablet

Azoalfa 50 Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Pegfilgrastim (Injection Route)

Sargramostim (Injection Route)

Lenograstim (Injection Route)

Leflunomide (Oral Route)

Filgrastim (Injection Route)

Frequently asked questions

What is Innomune Tablet prescribed for? How does it work?

How long do I need to take Innomune Tablet?

Is breastfeeding safe during Innomune Tablet treatment?

I have just started taking Innomune Tablet. What are the long-term side effects? Is there anything I should be looking out for?

Do I need any special tests while I am on Innomune Tablet?

Can Innomune Tablet cause cancer?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Rheumatoid Factor - Agglutination

Rheumatoid Factor - Turbidometry

Rheumatoid Factor IgG Antibody

References

User feedback

What are you using Innomune Tablet for?

How much was the improvement?

What were the side-effects while using Innomune Tablet?

How do you take Innomune Tablet?

Please rate Innomune Tablet on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests