Medicine Overview of Inflavan Tablet
Inflavan 10 mg Tablet is used in pain relief
. It relieves pain and inflammation in conditions like rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis.
Side Effects of Inflavan are Vomiting, Stomach pain, Nausea, Indigestion, Diarrhoea.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Inflavan 10 mg Tablet is to be taken with food.
Inflavan 10 mg Tablet is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that are responsible for inflammation (pain and swelling).
In Depth Information on Inflavan Tablet
- Inform your doctor if you have ever been diagnosed with kidney or liver problems.
It should be taken with food or milk to avoid getting an upset stomach.
- It can cause serious complications like stomach bleeding and kidney problems if taken for a long time.
Inflavan 10 mg Tablet can raise your risk of blood clots, heart attack, or a stroke.
- Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
Inflavan Tablet related warnings
Taking Piroxicam with alcohol may increase your risk of stomach bleeding.
WEIGH RISKS VS BENEFITS
Inflavan 10 mg Tablet is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Inflavan 10 mg Tablet is safe to use during lactation.
Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.
Inflavan 10 mg Tablet may make you feel dizzy, drowsy or affect your vision. Do not drive until your vision is clear.
Inflavan 10 mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Inflavan 10 mg Tablet may be needed. Please consult your doctor.
No dose adjustment is recommended in patients with mild to moderate kidney disease. Regular monitoring of kidney function test is advised while you are taking this medicine.
Inflavan 10 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Inflavan 10 mg Tablet may be needed. Please consult your doctor.
If you miss a dose of Inflavan 10 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Frequently asked questions about Inflavan Tablet
Q. What is the difference between Inflavan and diclofenac?
Both Inflavan and diclofenac are pain killers. However, piroxicam is a non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain) inhibitor whereas diclofenac has a bit more selectivity to a COX-2 enzyme. This selectivity of diclofenac is supposed to decrease the side effects as compared to Inflavan.
Q. What is the difference between Inflavan and naproxen?
Both Inflavan and naproxen are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, gastric side effects are lesser with naproxen as compared to Inflavan.
Q. What is the difference between Inflavan and meloxicam?
Both Inflavan and meloxicam are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, acute gastric side effects are lesser with meloxicam as compared to Inflavan.
Q. What is the difference between Inflavan and ketoprofen?
Both Inflavan and ketoprofen are pain killers. Both are non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain). Research studies have shown ketoprofen topical gel is better and effective as compared to Inflavan. Ketoprofen gel also showed excellent tolerability.
Q. What is the difference between Inflavan and tramadol?
Inflavan is a COX (cyclooxygenase -an enzyme responsible for inflammation and pain) whereas Tramadol is a narcotic-like painkiller. Tramadol is a habit forming medicine.
Q. What is the difference between Inflavan and nimesulide?
Both Inflavan and nimesulide are pain killers. However, Inflavan is a non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain) inhibitor whereas nimesulide is selective to the COX-2 enzyme. This selectivity of nimesulide is supposed to decrease the side effects as compared to piroxicam. It should not be used in children below 12 years of age.
Q. Can Inflavan be used in the treatment of chikungunya?
Usually, the platelet count does not dip in cases of chikungunya and painkillers like piroxicam can lead to the risk of increased bleeding tendency. So refrain from taking Inflavan or any painkiller in the case of any fever with joint pain. Consult your doctor before starting Inflavan.
Q. Are Inflavan and aspirin same?
No. Inflavan and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti-inflammatory and analgesic.
Q. Can Inflavan be used along with dexamethasone?
No. Inflavan should not be used with dexamethasone. They both increase each other's toxicity. There is an increased risk of GI ulceration.
Q. Can Inflavan be used with methocarbamol?
Yes. Methocarbamol can be used with Inflavan as no serious side effects are known. Inform your doctor before starting any of the medication.
Q. Can Inflavan be used along with paracetamol?
Yes. Paracetamol can be used with Inflavan as no serious side effects are known. Inform your doctor before starting any of the medication.
Yes. Inflavan is a non-steroidal anti-inflammatory drug (NSAID).
Q. Is Inflavan a sulfa drug?
Inflavan is a sulphur containing compound. Inflavan can cause serious adverse events in sensitive individuals. It can cause severe skin reactions like Steven Johnson Syndrome. Do inform your doctor if you have any kind of allergies.
Q. Is Inflavan a blood thinner?
No. Inflavan is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.
Q. Is Inflavan a muscle relaxant?
No. Inflavan is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.
Q. Is Inflavan a narcotic?
No. Inflavan is not a narcotic. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme to decrease the pain and inflammation.
Q. Can Inflavan be used in hypertension?
No. Inflavan is not a medication to control hypertension. It is important to note that Inflavan decreases the effectiveness of the antihypertensive medication when given together. Inform your doctor if you are taking antihypertensive medications before starting Inflavan.
Q. Can Inflavan be used along with Losartan?
No. Inflavan should not be combined with Losartan. It is important to note that Inflavan decreases the effectiveness of the antihypertensive medication like losartan when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Inflavan.
Q. Can Inflavan be used with Lisinopril?
No. Inflavan should be avoided with lisinopril. It is important to note that piroxicam decreases the effectiveness of the antihypertensive medication like lisinopril when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Inflavan.
Q. Can Inflavan be used with calcium channel blocker?
Yes. Inflavan can be taken with calcium channel blocker. NSAIDs have been observed to reduce the effectiveness of all antihypertensive drugs except calcium channel blockers (ref: White 2007)
Q. Can Inflavan be used with Tizanidine?
Yes, Inflavan can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.
Q. Why is beta cyclodextrin added to Inflavan?
Yes. Inflavan can be combined with beta-cyclodextrin. Research has shown that combining Inflavan with beta-cyclodextrin leads to faster onset of action of piroxicam and reduced gastric side effects.
Q. Are there any alternatives of Inflavan?
Yes. There are alternatives to Inflavan. Pain killers are prescribed according to the disease condition. Consult your doctor before starting piroxicam or changing it to other medication.
Q. What are the contraindications for Inflavan?
Contraindications to piroxicam are an allergy, bleeding tendency, duodenal/gastric/peptic ulcer, stomatitis, Systemic Lupus Erythematosus (SLE), ulcerative colitis, upper GI disease, late pregnancy, cardiac disease, hepatic impairment, renal impairment.
Q. Can Inflavan be used in the treatment of allergy?
No. Inflavan is not a drug to treat allergy. It is a pain killer.
Q. How long does Inflavan work?
Inflavan is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of piroxicam increases when given for few weeks.
Q. Can you get high by using Inflavan?
No. Inflavan is not known to cause high. It is a non-narcotic painkiller.
Q. Can Inflavan be used to treat menstrual cramp?
Inflavan is not approved for the treatment of menstrual cramps. Research studies have shown that piroxicam is quite effective in significantly decreasing the menstrual cramps.
Q. Can I use Inflavan for a migraine?
Inflavan is not approved for the treatment of migraine. Research studies have shown that Inflavan is effective in significantly decreasing the pain associated with migraine without aura.
Q. Is Inflavan effective in back pain management?
Yes. It can be given for decreasing the back pain. However, you should consult your doctor for the exact cause of your back pain and then start the treatment. Do not self-medicate yourself with Inflavan as the cause of back pain can be different for different person.
Q. Is Inflavan affective in gout management?
Yes. Inflavan can be given for the treatment of acute gout. Research studies have shown Inflavan to be highly effective in the treatment of acute gout.
Q. Can you donate blood when on the medication with Inflavan?
Yes. You can donate blood when on Inflavan. Do inform your doctor before donating blood.
Q. Can I use Inflavan if I am a diabetic?
Inflavan in a diabetic patient can only be taken only by consulting a doctor because these medicines have the propensity to cause renal failure when taken for a long period. Diabetes itself causes renal Inflavan so taking piroxicam can lead to increased risk of renal failure by many folds.
Q. Can I use Inflavan if I have a deranged renal function?
No. Inflavan should not be taken if you have a abnormal renal function because long-term administration of NSAIDs has resulted in renal papillary necrosis and another renal injury.
Q. Can Inflavan lead to skin reactions?
Yes. Inflavan is known to cause skin reactions which can be very severe such as exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. These serious events may occur without warning. You should inform your doctor if you feel you have a mild rash and immediately discontinue the drug.
Q. Can I use Inflavan if I am pregnant?
No. Inflavan should not be taken in pregnancy. It causes premature closure of the ductus arteriosus which can lead to fetal heart failure and death of the baby.
Q. Can I use Inflavan if I have peptic ulcer disease?
No. Inflavan is contraindicated in cases of active peptic ulcer disease. Inflavan is known to cause gastric ulceration and bleeding.
Q. Can I use Inflavan if I have asthma?
Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory (NSAID) drugs like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.
Q. Can Inflavan lead to difficulty in conception?
Yes. Inflavan can sometimes cause reversible infertility. Piroxicam by its mechanism of action may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.
Q. Can Inflavan be used with diuretics?
No. Inflavan should not be used with diuretics. Inflavan reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.
Q. Can Inflavan be used with lithium?
No. Inflavan should not be used with lithium. Inflavan leads to an elevation of plasma lithium levels and a reduction in renal lithium clearance. This is because of inhibition of renal prostaglandin synthesis by the NSAID. Consult and inform your doctor before starting this medication.
Q. Can Inflavan be used with warfarin?
No. Inflavan should be avoided with warfarin as they both lead to increase in bleeding tendencies. Inform your doctor if you are taking any of the medications. If given together then the therapy should be monitored closely.
Q. What increases the chances of getting a gastric ulcer when I am already taking Inflavan?
The chances of gastric ulceration increases if you take medicines like corticosteroids and anticoagulants. Long term use, alcohol, smoking and old age are few other factors which can increase the chances of ulceration.
Q. Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)/ Inflavan?
Patients who had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine or for pain right before or after heart bypass surgery.
Q. What are the serious side effects of Inflavan?
GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, serious skin side effects such as exfoliative, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis, liver failure, renal damage.
Severely interacts with other drugs like
Taking Inflavan with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
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