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Indopenem 1000mg Injection

Meropenem (1000mg)
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Indopenem 1000mg Injection is an antibiotic that is used to treat severe infections of the skin, lungs, stomach, urinary tract, blood, and brain (eg. meningitis). It works by killing the bacteria that cause these problems. However, it will not treat a viral infection.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 19 Jan 2026 | 11:02 PM (IST)
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General Information

The content is shown in English
Indopenem 1000mg Injection image
Indopenem 1000mg Injection image

Product introduction

Indopenem 1000mg Injection is commonly used to treat critically ill patients admitted to the hospital. This medicine is given by drip/infusion or by direct injection into a vein, under the supervision of a doctor or a nurse. The dose will depend on what type of infection you have, where it is in the body, and how serious it is. You should keep on taking the injection for as long as you have been prescribed, even if your symptoms quickly improve. If you stop taking it too early the infection may return or worsen.

Some people may develop side effects like headache, nausea, constipation, diarrhea, anemia, vomiting, and rash. These side effects are usually temporary and go away as your body adjusts to the medicine. Consult your doctor if these side effects bother you or do not go away.

Before starting treatment with this medicine, you should tell your doctor if you have epilepsy (seizures), liver or kidney problems or if you are allergic to any antibiotic. While using it, you may be advised blood tests to monitor your blood cell count and kidney function. This medicine is generally regarded as safe to use in pregnancy and breastfeeding if prescribed by the doctor.

Uses of Indopenem Injection

  • Severe bacterial infections

Benefits of Indopenem Injection

Severe bacterial infections
Indopenem 1000mg Injection belongs to a group of medicines called carbapenem antibiotics. It works by killing bacteria which can cause serious infections. It is a versatile medicine used to treat many different types of bacterial infections such as infections of the brain (meningitis), lungs (pneumonia), abdomen, urinary tract, skin, and blood. This medicine is usually given as an injection by a doctor or nurse.

Indopenem 1000mg Injection usually makes you feel better very quickly but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.

Side effects of Indopenem Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Indopenem
  • Vomiting
  • Nausea
  • Rash
  • Injection site inflammation
  • Sepsis
  • Apnea (absence of breathing)
  • Shock
  • Headache
  • Itching
  • Diarrhea
  • Anemia (low number of red blood cells)
  • Constipation

How to use Indopenem Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Indopenem Injection works

Indopenem 1000mg Injection is an antibiotic. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to survive.

Quick tips

  • Indopenem 1000mg Injection is an antibiotic that's usually only given in the hospital for serious infections.
  • Inform your doctor if you are allergic to penicillin or if you are taking any seizure medication before starting treatment with this medication.
  • Diarrhea may occur as a side effect. Inform your doctor if you develop severe stomach pain or if you find blood in your stools.
  • Your doctor may monitor your kidney function and blood count while you are having treatment with this medication.
  • Indopenem 1000mg Injection is an antibiotic that's usually only given in the hospital for serious infections.
  • It is given by a drip into a vein (intravenous infusion) over 20 to 60 minutes.
  • Inform your doctor if you are allergic to penicillin or if you are taking any seizure medication before starting treatment with this medication.
  • Diarrhea may occur as a side effect. Inform your doctor if you develop severe stomach pain or if you find blood in your stools.
  • Your doctor may monitor your liver and kidney function while you are having treatment with this medication.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Indopenem 1000mg Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Indopenem 1000mg Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Indopenem 1000mg Injection may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Indopenem 1000mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CAUTION
Indopenem 1000mg Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Indopenem 1000mg Injection in patients with liver disease.

Interaction with drugs

Taking Indopenem with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate

Probenecid (Oral Route)

Do not consume Meropenem with Probenecid. If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Probenecid may raise blood levels of Meropenem.
Moderate

Acenocoumarol (Oral Route)

Your doctor may monitor your blood coagulation status and adjust the dose of Acenocoumarol accordingly.
Moderate

Warfarin (Oral Route)

Your doctor may monitor your blood coagulation status and adjust the dose of Warfarin accordingly.
Mild

Risperidone (Oral Route)

Talk to your doctor if you notice any unusual symptoms. Meropenem may raise blood levels of the active form of Risperidone.
Mild

Risperidone (Injection Route)

Talk to your doctor if you notice any unusual symptoms. Meropenem may raise blood levels of the active form of Risperidone.

Frequently asked questions

Any previous history with any other medication should be informed to the doctor before starting your treatment with Indopenem 1000mg Injection. Medicines like Indopenem 1000mg Injection can interfere with valproic acid which is used for the treatment of epilepsy, making it less effective. So, the reason for the recent episode of seizure could be the result of such drug interaction. Generally, in cases like these, the doctor prescribes a different medicine.
Indopenem 1000mg Injection is a broad-spectrum antibiotic which means it can treat a variety of bacterial infections. It is used to treat infections affecting the lungs (pneumonia) and complicated infections of the urinary tract, abdomen, and skin and soft tissue infections. Along with that, it is also helpful in treating bacterial infection of the membranes that surround the brain and spinal cord (meningitis) and infections that occur during or after delivery.
Yes, Indopenem 1000mg Injection is effective only against bacteria. It is not effective against virus or fungal infections. Indopenem 1000mg Injection is effective against some bacteria which include Staphylococcus aureus, Streptococcus pneumoniae, S. pyogenes, S. viridans group, etc. Therefore, its use against any other type of bacteria should be avoided.
There are reports which suggest the occurrence of seizures or fits with the use of Indopenem 1000mg Injection. However, fits are more likely to occur in patients with a history of seizures or a brain lesion (wound, ulcer, abscess or tumor) or patients having bacterial meningitis or compromised kidney function. Consult your doctor to understand the exact reason.
The length of the treatment will be decided by your doctor. The doctor will decide the dose depending on your general health, the type of infection you have, and how well you respond to Indopenem 1000mg Injection. Consult your doctor if you are not sure.
It is common to have minor side effects such as nausea, vomiting, diarrhea, and headache with the use of Indopenem 1000mg Injection. However, these symptoms generally settle down with continued medication as the body adapts to the medicine. If the side effects bother you, inform your doctor. The doctor will suggest an alternative medicine if required. Serious side effects with Indopenem 1000mg Injection are very rare. In case you develop serious side effects, seek immediate medical advice.
You mustn't stop the treatment without consulting your doctor. Stopping the treatment may bring back the infection or you may develop resistance to Indopenem 1000mg Injection. Similar results may be seen if you skip any dose or are forgetful in taking the suggested doses. Therefore, it is recommended that you do not miss doses. If you do, take the missed dose as soon as you can and take the next dose as planned so that you stick to the same overall daily dose.

Fact Box

Chemical Class

Thienamycins

Habit Forming

No

Therapeutic Class

ANTI INFECTIVES

Action Class

Carbapenems

Related lab tests

References

  1. Petri WA Jr. Penicillins, Cephalosporins, and Other β -Lactam Antibiotics. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1500.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 866-67.
  3. Meropenem. Wilmington, DE: AstraZeneca Pharmaceuticals; 1996 [revised Nov. 2013]. [Accessed 29 Mar. 2019] (online) Available from:
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:
  5. Meropenem. Mumbai, Maharashtra: Pfizer Ltd.; 2025. [Accessed 19 Jan. 2026]. (online). Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Indoco Remedies Ltd
Address: Indoco House, 166 CST Road, Santacruz (E), Mumbai 400 098, INDIA

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Indopenem 1000mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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