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Meropenem is used in serious bacterial infections

How it works

Meropenem is an antibiotic. It kills the bacteria by attacking their cell wall. Specifically, it prevents the synthesis of a substance in the cell wall called peptidoglycan, which provides the cell wall with the strength required for survival of bacteria in human body.

Common side effects

Nausea, Vomiting, Seizure

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Expert advice

Meropenem is given as an injection directly into a vein by a doctor or nurse using water for injections or a suitable infusion fluid. Do not start or continue the meropenem and consult your doctor:
  • If you have kidney or liver problems.
  • If you have a history of seizures or central nervous system problems (e.g. brain lesions).
  • If you experience severe and persistent diarrhea after taking antibiotics.
  • If you are taking other drugs like probenecid, valproic acid, or oral anticoagulants like warfarin.
  • If you are pregnant, planning to become pregnant or breastfeeding.

Frequently asked questions



Is meropenem a penicillin, cephalosporin, or beta lactam drug?
Meropenem is not a penicillin or cephalosporin drug. It is a carbapenem beta-lactam antibiotic


Is meropenem safe?
Meropenem is relatively safe if used at prescribed doses for the prescribed duration as advised by your doctor


Is meropenem dialyzable?
Yes, meropenem is dialyzable

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Is meropenem compatible with vancomycin, or potassium?
Meropenem may be compatible with potassium or vancomycin. Please consult your doctor before taking the drug


Is meropenem nephrotoxic, vesicant or cause thrombocytopenia?
Meropenem may be nephrotoxic, vesicant, and may cause thrombocytopenia. Please consult your doctor if you experience these side effects


What organisms does meropenem cover?
Meropenem is active against gram-positive and gram-negative bacteria, aerobes as well as anaerobes. It is effective against enterococcus, streptococcus, and methicillin-sensitive Staphylococcus aureus (MSSA), but not effective against listeria or methicillin-resistant Staphylococcus aureus.

Content on this page was last updated on 13 February, 2017, by Dr. Varun Gupta (MD Pharmacology)