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Meropenem

INFORMATION

Uses

Meropenem is used in serious bacterial infections.

How it works

Meropenem is an antibiotic. It kills the bacteria by attacking their cell wall. Specifically, it prevents the synthesis of a substance in the cell wall called peptidoglycan, which provides the cell wall with the strength required for survival of bacteria in human body.

Common side effects

Nausea, Numbness, Pale red skin, Itchy rash, Rash, Abdominal pain, Abnormal blood cell count, Application site pain, Application site inflammation, Burning sensation, Diarrhoea, Fungal infection of mouth, Fungal infection of vagina, Headache, Increased bilirubin in the blood, Increased blood platelets, Itching, Pricking sensation, Tingling sensation, Increased blood urea, Vomiting

AVAILABLE MEDICINE

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Expert advice

Meropenem is given as an injection directly into a vein by a doctor or nurse using water for injections or a suitable infusion fluid. Do not start or continue the meropenem and consult your doctor:
  • If you have kidney or liver problems.
  • If you have a history of seizures or central nervous system problems (e.g. brain lesions).
  • If you experience severe and persistent diarrhea after taking antibiotics.
  • If you are taking other drugs like probenecid, valproic acid, or oral anticoagulants like warfarin.
  • If you are pregnant, planning to become pregnant or breastfeeding.

Frequently asked questions

Meropenem

Q.Is meropenem a penicillin, cephalosporin, or beta lactam drug?
Meropenem is not a penicillin or cephalosporin drug. It is a carbapenem beta-lactam antibiotic

Q.Is meropenem safe?
Meropenem is relatively safe if used at prescribed doses for the prescribed duration as advised by your doctor

Q.Is meropenem dialyzable?
Yes, meropenem is dialyzable

Q.Is meropenem compatible with vancomycin, or potassium?
Meropenem may be compatible with potassium or vancomycin. Please consult your doctor before taking the drug

Q.Is meropenem nephrotoxic, vesicant or cause thrombocytopenia?
Meropenem may be nephrotoxic, vesicant, and may cause thrombocytopenia. Please consult your doctor if you experience these side effects

Q.What organisms does meropenem cover?
Meropenem is active against gram-positive and gram-negative bacteria, aerobes as well as anaerobes. It is effective against enterococcus, streptococcus, and methicillin-sensitive Staphylococcus aureus (MSSA), but not effective against listeria or methicillin-resistant Staphylococcus aureus.


Content on this page was last updated on 24 November, 2016, by Dr. Varun Gupta (MD Pharmacology)