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Ilosure 4 Tablet

Iloperidone (4mg)
Genuine
Authenticity Assured
Prescription
required
Ilosure 4 Tablet is used in the treatment of schizophrenia (a mental disorder that can result in hallucinations or delusions and also adversely affects a person’s ability to think and behave) and mania. It can also be used to treat depression and bipolar disorders.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 17 Apr 2026 | 12:03 PM (IST)
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Ilosure 4 Tablet image
Ilosure 4 Tablet image
Ilosure 4 Tablet image
Ilosure 4 Tablet image
Ilosure 4 Tablet image
Ilosure 4 Tablet image

Product introduction

Ilosure 4 Tablet may be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember. Do not skip any doses and finish the full course of treatment even if you feel better. This medication mustn't be stopped suddenly without talking to your doctor as it may worsen your symptoms.

Some common side effects of this medicine include fatigue, dryness in the mouth, sleepiness, and nasal congestion. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, so drink plenty of fluids and it is better to rise slowly if you have been sitting or lying down. It also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may increase your weight. However, modifying your lifestyle by having a healthy diet and exercising regularly can reduce this side effect.

Before taking this medicine it is important to inform your doctor if your suffering from high body temperature and muscle stiffness (neuroleptic malignant syndrome), have had abnormal tongue or face movements (dyskinesia), heart disease, diabetes, Parkinson’s disease, dementia, fits (epilepsy), difficulty in swallowing (dysphagia), or liver problems.

Uses of Ilosure Tablet

Benefits of Ilosure Tablet

Mania
Mania means extremely excited or elevated mood. Ilosure 4 Tablet helps calm the mood and relax the nerves. This stabilises the mood and prevents the symptoms of mania from recurring again. Taking Ilosure 4 Tablet will ensure that you have a better social life and are able to do daily activities more comfortably.
Schizophrenia
Schizophrenia is a mental disorder in which a person’s thinking ability, feelings and behavior become abnormal. Ilosure 4 Tablet helps restore the chemical imbalances in the brain that are responsible for such changes. It improves thoughts, behavior and enhances the quality of life.

Side effects of Ilosure Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Ilosure
  • Dizziness
  • Dryness in mouth
  • Fatigue
  • Nasal congestion (stuffy nose)
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Sleepiness
  • Weight gain

How to use Ilosure Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ilosure 4 Tablet may be taken with or without food.

How Ilosure Tablet works

Ilosure 4 Tablet is an atypical antipsychotic. It works by modulating the action of certain chemical messengers in the brain that affect thoughts.

Quick tips

  • Take it at bedtime to avoid feeling sleepy during the day.
  • It may take 2-6 weeks to feel the medication's full effects.
  • To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • Use caution while driving or doing anything that requires concentration as Ilosure 4 Tablet can cause dizziness and sleepiness.
  • It may cause an increase in weight, blood sugar, cholesterol, and triglycerides (fat). Eat healthy and exercise regularly.
  • Do not stop taking Ilosure 4 Tablet without talking to your doctor first as it may cause a worsening of symptoms.
     

Safety advice

Alcohol

Alcohol

UNSAFE
Do not drink alcohol while you are taking this medicine. Ilosure 4 Tablet may cause excessive drowsiness when taken with alcohol.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Ilosure 4 Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Ilosure 4 Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
Ilosure 4 Tablet may cause side effects that could affect your ability to drive.
Kidney

Kidney

CAUTION
Ilosure 4 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Ilosure 4 Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Use of Ilosure 4 Tablet is not recommended in patients with severe liver disease.

Interaction with drugs

Taking Ilosure with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Amiodarone (Oral Route)

Do not consume Amiodarone with Iloperidone.
Life-threatening

Escitalopram Oxalate (Oral Route)

Do not consume Escitalopram Oxalate with Iloperidone.
Life-threatening

Haloperidol (Oral Route)

Do not consume Haloperidol with Iloperidone.
Life-threatening

Ondansetron (Oral Route)

Do not consume Ondansetron with Iloperidone.
Life-threatening

Apomorphine (Sublingual route)

Do not consume Iloperidone with Apomorphine.

Frequently asked questions

Ilosure 4 Tablet is an antipsychotic medicine used to treat schizophrenia in adults. It helps manage symptoms like hallucinations, delusions, and disorganized thinking.
Serious side effects of Ilosure 4 Tablet may include irregular heartbeat (QT prolongation), low blood pressure when standing, tardive dyskinesia (uncontrollable movements), and neuroleptic malignant syndrome (fever, muscle stiffness). Seek medical attention if you experience any of these.
No. Ilosure 4 Tablet is not approved for treating dementia-related psychosis in older adults. It may increase the risk of stroke or death in such patients.
No. Do not stop taking Ilosure 4 Tablet suddenly without medical advice. Stopping it abruptly can cause withdrawal symptoms or a return of psychotic symptoms.
While using Ilosure 4 Tablet, you should avoid alcohol, rise slowly from sitting or lying positions, do not drive or operate machinery until you know how it affects you, stay hydrated, and avoid overheating of the body.
Individuals should not take Ilosure 4 Tablet if they have heart rhythm problems (like QT prolongation), are taking medications that affect heart rhythm, or are allergic to iloperidone or any of the ingredients in Ilosure 4 Tablet.
Ilosure 4 Tablet may take several days to weeks for symptoms of schizophrenia to improve. Do not stop taking it just because you do not feel immediate relief.
Yes, weight gain is a possible side effect of Ilosure 4 Tablet. Your doctor may monitor your weight, blood sugar, and cholesterol during treatment.

Fact Box

Chemical Class

Alkyl- phenylketones

Habit Forming

No

Therapeutic Class

NEURO CNS

Action Class

Atypical Antipsychotics

References

  1. Stahl SM, editor. Iloperidone. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 301-305.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 690-91.
  3. Stahl SM. Iloperidone. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, NY: Cambridge University Press; 2014. pp. 301-304.
  4. Iloperidone. Washington, D.C.: Vanda Pharmaceuticals Inc.; 2009 [revised Jan. 2016]. [Accessed 25 Mar. 2019] (online) Available from:
  5. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Iloperidone. [Updated 2018 Dec 3]. [Accessed 20 Feb. 2020] (online) Available from:
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:
  7. Iloperidone. Washington, D.C., USA: Vanda Pharmaceuticals Inc.; 2025. [Accessed 17 APr. 2026] (online).
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User feedback

Twice A Day
51%
Once A Day
46%
Thrice A Day
3%
Mania
100%
Excellent
67%
Average
33%
Weight gain
100%
Empty stomach
100%
Average
100%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Sun Pharmaceutical Industries Ltd
Address: Khasra No. 1335-1340,Near EPIP- I, Vill - Bhatoli Kalan ,Baddi, Solan, Himachal Pradesh, 173205 || Plot no 107/108,Namli block , Ranipool, East Sikkim 737135 || Acme Plaza, Andheri-Kurla Road, Andheri (East), Mumbai, Maharashtra -400059

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Ilosure 4 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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