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Ifyclodon 12.5mg Tablet

Written By Dr. Syeda Aafia, MBA, BDS
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS
Last updated on 25 Nov 2025 | 03:05 PM (IST)
Ifyclodon 12.5mg Tablet is a diuretic (water pill) medicine used to treat hypertension (high blood pressure). This medicine reduces excess fluid levels in the body and treats edema (fluid overload) associated with heart, liver, kidney, or lung disease.
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General Information

The content is shown in English
Ifyclodon 12.5mg Tablet image
Ifyclodon 12.5mg Tablet image

Product introduction

Ifyclodon 12.5mg Tablet makes you lose excess water through urine. It may be used alone or in combination with other medicines. This medicine should be taken only during day time to avoid frequent urination at night. You must take this medicine in the dose and duration as advised by the doctor and never stop it abruptly without consulting the doctor. Most people with high blood pressure do not feel ill, but if you stop taking this medicine, your condition could get worse. This may lead to your blood pressure rising again and increase your risk of heart disease and stroke.


Common side effects of this medicine include loss of appetite, low sodium levels and dizziness. Consult your doctor if these side effects bother you. Before taking this medicine, it is better to let your doctor know if you are suffering from any kidney or liver disease. Also, pregnant women and breastfeeding mothers should consult a doctor before taking it. You must inform the doctor about all the other medicines that you are taking apart from this medicine.


It is important to have your blood pressure checked regularly. This medicine is only one part of a treatment program which should also include a healthy diet, regular exercise, smoking cessation, moderation of alcohol intake, and weight reduction. You can eat normally while taking this medicine, but try to reduce your salt intake.


Uses of Ifyclodon Tablet

Benefits of Ifyclodon Tablet

Hypertension (high blood pressure)
Ifyclodon 12.5mg Tablet used to help manage high blood pressure (hypertension), which in turn reduces the risk of serious health problems such as heart attacks, strokes, and kidney damage. By helping the body get rid of excess salt and water, it lowers the pressure in blood vessels and improves circulation. Regular use, as prescribed, can support long-term heart health and may also help reduce swelling in certain conditions.

Side effects of Ifyclodon Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Ifyclodon
  • Dizziness
  • Gastrointestinal disturbance
  • Decreased sodium level in blood
  • Decreased magnesium level in blood
  • Increased glucose level in blood
  • Rash
  • Hypotension (low blood pressure)

How to use Ifyclodon Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ifyclodon 12.5mg Tablet should be taken with or after food.

How Ifyclodon Tablet works

Ifyclodon 12.5mg Tablet is a diuretic which lowers blood pressure by removing extra water and certain electrolytes from the body. Over time it also relaxes blood vessels and improves blood flow.

Quick tips

  • Take it in the morning with breakfast to avoid getting up at night to urinate.
  • It makes you feel dizzy. Avoid driving and attention requiring activity until you know how it affects you.
  • Avoid alcohol intake while taking Ifyclodon 12.5mg Tablet as it may increase the dizziness. 
  • It may cause a sudden drop of sodium level in blood. Avoid low sodium diet while you are taking this medication.
  • Monitor your blood pressure after starting Ifyclodon 12.5mg Tablet, and notify your doctor if it does not lower down.
  • Notify your doctor if you experience dizziness, tiredness, or muscle weakness that does not go away.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. 
  • Ifyclodon 12.5mg Tablet helps lower blood pressure and also removes excess water from your body.
  • Take it in the morning with breakfast to avoid getting up at night to urinate.
  • It may cause dizziness in the initial days of treatment.
  • Monitor your blood pressure after starting Ifyclodon 12.5mg Tablet, and notify your doctor if it does not lower down.
  • Notify your doctor if you experience dizziness, tiredness, or muscle weakness that does not go away.
  • You may be asked to get regular blood tests done to monitor your kidney function.
  • It makes you feel dizzy. Avoid driving and attention requiring activity until you know how it affects you.
  • Avoid alcohol intake while taking Ifyclodon 12.5mg Tablet as it may increase the dizziness. 
  • It may cause a sudden drop of sodium level in blood. Avoid low sodium diet while you are taking this medication.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. 

Safety advice

Alcohol

Alcohol

UNSAFE
Do not drink alcohol while you are taking this medicine. Ifyclodon 12.5mg Tablet may cause excessive drowsiness when taken with alcohol.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Ifyclodon 12.5mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

UNSAFE
Ifyclodon 12.5mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Its slow clearance may lead to accumulation in the infant.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Ifyclodon 12.5mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CAUTION
Ifyclodon 12.5mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Use of Ifyclodon 12.5mg Tablet is not recommended in these patients.
Liver

Liver

CAUTION
Ifyclodon 12.5mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Use of Ifyclodon 12.5mg Tablet is not recommended in patients with severe liver disease.

Interaction with drugs

Taking Ifyclodon with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Lithium carbonate (Oral Route)

Do not consume Lithium carbonate with Chlorthalidone. If concurrent use is essential, your doctor may regularly monitor Lithium carbonate and potassium levels. Watch out for symptoms such as impaired coordination, double vision, dizziness, or confusion, and consult your doctor if you experience them. They may adjust the dose of Lithium carbonate accordingly.
Moderate

Chloroquine (Oral Route)

Your doctor may monitor your potassium levels closely.
Moderate

Dexamethasone (Oral Route)

If concurrent use is essential, your doctor may monitor your potassium levels along with your overall treatment and adjust the doses as per the observations.
Moderate

Loperamide (Oral Route)

Your doctor may monitor your potassium levels closely.
Moderate

Azithromycin (Oral Route)

Your doctor may monitor your potassium levels closely.

Frequently asked questions

No, do not take alcohol while on treatment with Ifyclodon 12.5mg Tablet. Taking alcohol with Ifyclodon 12.5mg Tablet may lower your blood pressure suddenly making you feel dizzy and lightheaded.
This combination is best avoided since the two medicines may interfere with each other. However, if your doctor advises you to take both ibuprofen and Ifyclodon 12.5mg Tablet, you will need to keep a regular check on your blood pressure and also monitor your kidney function tests.
Yes, Ifyclodon 12.5mg Tablet may raise uric acid levels. However, the occurrence of gout due to Ifyclodon 12.5mg Tablet is very rare.
No, there have been no reports of Ifyclodon 12.5mg Tablet causing skin cancer. However, in rare cases, this medicine can make the skin more sensitive to sunlight than usual. If you are exposed to direct sunlight you may get skin rash, so wear protective clothing and use sunscreen.

Fact Box

Chemical Class

Isoindolones

Habit Forming

No

Therapeutic Class

CARDIAC

Action Class

Thiazide Diuretics

Related lab tests

References

  1. Michel T, Hoffman BB. Treatment of Myocardial Ischemia and Hypertension. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 769.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 257.
  3. Opie LH, Krum H, Victor RG, et al. Antihypertensive Therapies. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. p. 241.
  4. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 15 Mar. 2019] (online) Available from:
  5. Central Drugs Standard Control Organisation (CDSCO). Chlorthalidone. [Accessed 15 Mar. 2019] (online) Available from:
  6. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006. Chlorthalidone. [Updated 2021 Jan 18]. [Accessed 12 Jun, 2023] (online) Available from:
  7. Chlorthalidone [Product Information]. AA Pharma Inc.; 2022 [Accessed 03/07/2025] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Syntonic Lifesciences
Address: Syntonic Life Sciences, Shri Sai Market, Opposite Hotel Marc Royale Kalka- Zirakpur Highway, Dhakoli, Zirakpur-140603, Punjab, India

Vendor Details

Country of origin: India
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