Gynapres L Tablet

Written By Dr. Lipika Khurana, PGDHHM, BDS

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 22 Jan 2026 | 12:51 PM (IST)

Gynapres L Tablet is a medicine used for treating high blood pressure (hypertension) and heart-related chest pain (angina). It is also effective for treating high blood pressure in pregnancy. It lowers blood pressure and thus helps in preventing future stroke and heart attack.

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General Information

Contains

Labetalol (NA)

Marketer

Mankind Pharma Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Gynapres L Tablet should be taken with food. This medicine may be used alone or in combination with other medicines. Use it along with a healthy diet, regular exercise, and without smoking for best results. Since it can cause serious withdrawal effects, it should not be stopped abruptly.

Some common side effects of this medicine include hypersensitivity (rash, pruritus, angioedema), tingling sensation in scalp, heart failure, increased liver function tests, difficulty in utrination, erectile dysfunction, and drug fever. These side effects usually get better with time, however, if they persist or get worse, let your doctor know.

Uses of Gynapres L Tablet

Benefits of Gynapres L Tablet

Angina (heart-related chest pain)
Gynapres L Tablet relaxes the blood vessels so that blood can flow more easily around your body and makes sure that your heart is getting a good supply of oxygen. This makes it less likely that you will suffer chest pain caused by angina. This medicine can help increase your ability to exercise and go about your daily life more easily by reducing the frequency of angina attacks. You should take it regularly and as long as it is prescribed for it to work effectively.

Hypertension (high blood pressure)
Gynapres L Tablet works by blocking the effects of some chemicals on your heart and blood vessels. It slows down your heart rate and helps the heart to beat with less force. This effectively lowers blood pressure. It must be taken regularly as prescribed to be effective. You do not usually feel any direct benefit from taking this medicine, but it works in the long term to keep you well.

Prevention of heart attack and stroke
If your blood pressure is controlled you are less at risk of having a heart attack or stroke. Gynapres L Tablet reduces the chances of heart diseases and helps you remain healthier for longer. Take it regularly and make appropriate lifestyle changes, such as eating healthy and staying active, to maximize the effectiveness of this medicine.

Side effects of Gynapres L Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Gynapres L

Dizziness
Erectile dysfunction
Ejaculation disorder
Breathlessness
Fever
Paresthesia (tingling or pricking sensation)
Difficulty in urination
Heart failure
Drug fever
Hypersensitivity
Abnormal liver function tests

How to use Gynapres L Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Gynapres L Tablet should be taken with or after food.

How Gynapres L Tablet works

Gynapres L Tablet is an alpha and beta blocker. It works by slowing down the heart rate and relaxing blood vessels which makes the heart more efficient at pumping blood around the body.

Quick tips

Check your blood pressure 1 week after starting Gynapres L Tablet, and inform your doctor if it has not improved.
Gynapres L Tablet may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
It may cause you to feel lightheaded or weak especially when you stand up (orthostatic hypotension). Rise slowly if you have been sitting or lying down.
It is best to avoid drinking alcohol while taking Gynapres L Tablet as it may make the side effects worse.
Do not stop taking Gynapres L Tablet suddenly as it can cause your blood pressure to rise suddenly, thereby increasing the risk of heart attack and stroke.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Gynapres L Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Gynapres L Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CAUTION

Gynapres L Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

UNSAFE

Gynapres L Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

SAFE IF PRESCRIBED

Gynapres L Tablet is safe to use in patients with kidney disease. No dose adjustment is recommended.
However, talk to your doctor if you have any underlying kidney disease. Regular monitoring of blood pressure is recommended for better dose adjustment.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Gynapres L Tablet in patients with liver disease.

Interaction with drugs

Taking Gynapres L with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Aminophylline (Oral Route)

Do not consume Aminophylline with Labetalol.

Life-threatening

Theophylline (Oral Route)

Do not use Labetalol with Theophylline in any form if you have asthma or breathing issues, as it may result in excessive breathlessness or coughing.

Life-threatening

Theophylline (Injection Route)

Do not use Labetalol with Theophylline in any form if you have asthma or breathing issues, as it may result in excessive breathlessness or coughing.

Severe

Lidocaine (Injection Route)

watch out for symptoms such as breathlessness, fatigue, drowsiness, sedation or faintness or vomiting and consult your doctor if you experience them. Labetalol may raise blood levels of Lidocaine.

Severe

Adrenaline (Injection Route)

watch out for symptoms such as breathlessness, fatigue, drowsiness, sedation or faintness or vomiting and consult your doctor if you experience them. Labetalol may reduce efficacy of Adrenaline.

Frequently asked questions

Is Gynapres L Tablet safe?

Gynapres L Tablet is generally considered a safe medicine if it is taken as directed by the doctor. The side effects that result with use of Gynapres L Tablet occur during the first few weeks of treatment and disappear with time.

Why is Gynapres L Tablet used in pregnancy?

It is important to appropriately treat high blood pressure in pregnancy. Studies have shown that poorly controlled high blood pressure in pregnancy can lead to an increased risk of certain birth defects, stillbirth, reduced growth of the baby within the womb, and premature birth. For some women with high blood pressure, treatment with Gynapres L Tablet in pregnancy might be considered to be the best option. Your doctor is the best person to help you decide what is right for you and your baby.

Does Gynapres L Tablet cause itching?

Yes, itchy skin, a rash or tingly scalp are common side effects of Gynapres L Tablet. Speak to your doctor if the itchiness or rash gets worse or lasts for more than a week.

Is it safe to use Gynapres L Tablet in patients with diabetes?

Diabetic patients while using Gynapres L Tablet should regularly check the blood sugar levels. Gynapres L Tablet may make it difficult to recognize the warning signs of low blood sugar such as shaking and a racing heartbeat. Consult your doctor if the blood sugar levels are reduced while taking Gynapres L Tablet.

Does Gynapres L Tablet affect heart rate?

Gynapres L Tablet slows down your heart rate and makes it easier for your heart to pump blood around your body. Your doctor may regularly check your blood pressure and pulse (heart rate) during therapy to determine your response to the medicine.

What can happen if I stop taking Gynapres L Tablet?

Do not stop taking Gynapres L Tablet without talking to your doctor. Stopping Gynapres L Tablet suddenly may cause serious heart problems such as angina (chest pain) or even a heart attack. If you need to stop taking Gynapres L Tablet, your doctor will reduce the dose slowly over 1 or 2 weeks.

Will I need to stop taking Gynapres L Tablet before surgery?

Your doctor may advise you to stop taking Gynapres L Tablet for 24 hours before surgery. This is because Gynapres L Tablet can lower your blood pressure too much when its use is combined with some anesthetics. So, tell your doctor that you're taking Gynapres L Tablet if you're going to be put to sleep using a general anesthetic or are scheduled to have any kind of major operation.

What happens on taking more than the recommended dose of Gynapres L Tablet?

Taking more than the recommended dose of Gynapres L Tablet can lead to a drop in blood pressure and slowing of the heart rate, difficulty breathing, or a drop in blood sugar, which can cause sweating or confusion. If you take too many tablets, tell your doctor immediately or contact the hospital emergency department nearest to you.

How long does Gynapres L Tablet take to work?

If you are taking Gynapres L Tablet for high blood pressure, it may lower your BP within 1-3 hours of taking it. You may not feel any different, but this does not mean that the medicine is not working, and it is important to keep taking it. On the other hand, if you are taking it for angina, it will probably take a few days for the medicine to reduce the pain. You may still have chest pain during this time or it may get worse.

Fact Box

Chemical Class

Salicylamides

Habit Forming

Therapeutic Class

CARDIAC

Action Class

Alpha & beta blocker

Related lab tests

Kidney Function Test

References

Westfall TC, WestfallIn DP. Adrenergic Agonists and Antagonists. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 328-29.
Benowitz NL. Antihypertensive Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 176-77.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 764-65.
Labetalol hydrochloride tablets. Fort Lauderdale, Florida: Zenith Goldline Pharmaceuticals, Inc.; 1997. [Accessed 19 Mar. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 19 Mar. 2019] (online) Available from:
Labetalol Hydrochloride. Pine Brook, NJ: Alvogen, Inc.; 2024 [Accessed 05 Jan. 2026] (online). Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Mankind Pharma Ltd
Address: 208, Okhla Industrial Estate, Phase III, New Delhi - 110020

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Gynapres L Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Gynapres L Tablet

Benefits of Gynapres L Tablet

Side effects of Gynapres L Tablet

How to use Gynapres L Tablet

How Gynapres L Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Aminophylline (Oral Route)

Theophylline (Oral Route)

Theophylline (Injection Route)

Lidocaine (Injection Route)

Adrenaline (Injection Route)

Frequently asked questions

Is Gynapres L Tablet safe?

Why is Gynapres L Tablet used in pregnancy?

Does Gynapres L Tablet cause itching?

Is it safe to use Gynapres L Tablet in patients with diabetes?

Does Gynapres L Tablet affect heart rate?

What can happen if I stop taking Gynapres L Tablet?

Will I need to stop taking Gynapres L Tablet before surgery?

What happens on taking more than the recommended dose of Gynapres L Tablet?

How long does Gynapres L Tablet take to work?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Kidney Function Test

References

User feedback

Patients taking Gynapres L Tablet

How much was the improvement?

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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