Glivec 100mg Tablet
Product introduction
Glivec 100mg Tablet is used to treat several types of cancers. It is most commonly prescribed to treat blood cancers (chronic myeloid leukemia and acute lymphocytic leukemia) and gastrointestinal stromal tumors. It works by targeting specific proteins that contribute to the growth and spread of cancer cells.
Glivec 100mg Tablet is also used for treatment of a skin tumor called dermatofibrosarcoma protuberans and a type of bone marrow condition called aggressive systemic mastocytosis. The medicine should be taken with food. Take it at the same time each day to get the most benefit. Continue taking it as long as your doctor advises for it. The duration of treatment varies according to your need and response to treatment. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include edema, nausea, vomiting, muscle cramps, musculoskeletal pain, diarrhea, rash, fatigue, and abdominal pain. Let your doctor know if you experience unexpected rapid weight gain. Your doctor may advise for regular monitoring of blood cells and liver function while you are taking this medicine. Do not drive or do anything requiring mental focus if you experience dizziness and blurry vision.
Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses of Glivec Tablet
Benefits of Glivec Tablet
In Treatment of Cancer
In several types of cancers like blood cancers, gastrointestinal stromal tumors, skin cancer (dermatofibrosarcoma protuberans), and bone marrow condition (aggressive systemic mastocytosis), Glivec 100mg Tablet targets the specific proteins that contribute to the growth and spread of cancer cells. By stopping these proteins, the medicine slows down or even stops the growth of cancer. This helps shrink tumors, slow down their growth, and make the patients feel better.
Side effects of Glivec Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Glivec
- Muscle cramp
- Musculoskeletal (bone, muscle or joint) pain
- Rash
- Weight gain
- Edema (swelling)
- Nausea
- Vomiting
- Diarrhea
- Fatigue
- Abdominal pain
- Bleeding
- Breathing problems
- Cough
- Dizziness
- Dry eye
- Hemorrhage
How to use Glivec Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Glivec 100mg Tablet should be taken with or after food.
How Glivec Tablet works
Glivec 100mg Tablet is an anti-cancer medication. A protein enzyme, bcr-abl tyrosine kinase, responsible for the growth of abnormal proliferation of cancer cells. This medicine inhibits the proliferation and induces apoptosis (planned cell death) in bcr-abl positive cells (cancer cells). This is how it works to stop or slow the spread of cancer.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Glivec 100mg Tablet. Please consult your doctor.
Pregnancy
UNSAFE
Glivec 100mg Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding
UNSAFE
Glivec 100mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Glivec 100mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Glivec 100mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver
CAUTION
Glivec 100mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
What if you forget to take Glivec Tablet?
If you miss a dose of Glivec 100mg Tablet, skip it and continue with your normal schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- Always take it with food and a full glass of water to prevent nausea.
- It may cause dizziness or blurred vision. Do not drive or do anything requiring concentration until you know how it affects you.
- Water retention and swelling are very common side effects of Glivec 100mg Tablet. Notify your doctor if you have unexpected rapid weight gain.
- Do not change the dose or discontinue use without consulting your doctor.
- Notify your doctor about all the medications you are taking, including over the counter medicines and dietary supplements.
- Your doctor may get regular blood tests done to monitor your liver function and the number of blood cells in your blood.
Fact Box
Chemical Class
Benzamide derivative
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Tyrosine Kinase Inhibitors (TKIs)
Interaction with drugs
Taking Glivec with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
If concurrent use is essential, watch out for symptoms such as bruising, pink urine, nosebleeds, diarrhea, stomach cramps, or bloating, and consult your doctor if you experience th
Do not consume Atorvastatin with Imatinib mesylate. If concurrent use is essential, watch out for symptoms such as unexplained muscle pain, tenderness or weakness and consult your
Watch out for symptoms of Imatinib mesylate side effects such as nausea, vomiting, headache, dizziness, constipation or weakness and consult your doctor if you experience them. The
Do not consume Pimozide with Imatinib mesylate.
Concomitant use may affect heart rhythm and can be fatal.
Concomitant use is not recommended. Please consult with your doctor. Imatinib mesylate may raise blood levels of Vinblastine.
Concurrent use may cause hairloss, drop in blood cell
Patient concerns
User feedback
Patients taking Glivec 100mg Tablet
Once A Day
62%
Twice A Day
38%
What are you using Glivec Tablet for?
Blood cancer *
67%
Gastrointesti*
33%
*Blood cancer (Chronic myeloid leukaemia), Gastrointestinal stromal tumour
How much was the improvement?
Average
100%
What were the side-effects while using Glivec 100mg Tablet?
Vomiting
100%
How do you take Glivec Tablet?
With or witho*
50%
With food
50%
*With or without food
Please rate Glivec 100mg Tablet on price
Not Expensive
50%
Expensive
50%
FAQs
Can Glivec 100mg Tablet be taken with food?
Yes, the best way to take it is with a glass of water and food. This prevents irritation in the food pipe and stomach. If you cannot swallow it, put the tablets in a glass of water or apple juice (approximately 50 ml for a 100 mg tablet and 200 ml for a 400 mg tablet). Stir it with a spoon to make it uniform and drink it immediately.
Is it safe to drive while taking Glivec 100mg Tablet?
Glivec 100mg Tablet may cause dizziness, lightheadedness or drowsiness in some people. Make sure you know how you react to it before you drive a car or operate machinery.
What precautions need to be followed while taking Glivec 100mg Tablet?
While taking Glivec 100mg Tablet, make sure you follow all the instructions given by your doctor, carefully and keep all appointments. You will need regular follow-up to ensure that the treatment is working. Regular blood tests, weight checks, and urine tests may be required to find out any side effects before it becomes serious. Make sure you use a method of contraception to prevent pregnancy during treatment with Glivec 100mg Tablet. Tell your doctor immediately if you become pregnant while you are taking this medicine. If you are about to start taking any new medicine, remind your doctor that you are taking Glivec 100mg Tablet.
Ever since I started using Glivec 100mg Tablet, I have noticed that I develop rashes and severe itching when I have sun exposure. Is it because of the medicine or the disease?
This medicine may make your skin much more sensitive to sunlight than it normally is. Exposure to sunlight may cause skin rash, itching, redness or severe sunburn. When you are outdoors, wear protective clothing and use a sunscreen with an SPF of 15 or higher. If you feel a burning sensation on your skin, tell your doctor.
The doctor has advised me not to take any medicine on my own while taking Glivec 100mg Tablet. Should I consult my doctor even if I need to take paracetamol for my fever?
Yes, there are a number of medicines which interfere with Glivec 100mg Tablet, including paracetamol. Therefore you should not self medicate while taking Glivec 100mg Tablet. Other medicines which interfere with Glivec 100mg Tablet include cyclosporin, dexamethasone (a steroid), warfarin, antiviral medicines which treat AIDS and some medicines which treat bacterial infections, high cholesterol, high blood pressure, heart problems, and mental disorders and depression. Consult your doctor before taking any medicine, and inform him that you are on Glivec 100mg Tablet therapy.
Can I expect that if I take Glivec 100mg Tablet regularly and as advised by the doctor for CML, I will be cured?
Glivec 100mg Tablet has proved effective in many cases of CML. It is also noticed that the chances of survival increase after taking this medicine. The doctor who is treating CML can tell you better. The doctor will analyze your current state, blood test results, response to treatment, any other medical illness which you may be having, etc. and tell you.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1732-34.
- Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 953.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 692-94.
- Imatinib mesylate. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2001 [revised Jan 2012]. [Accessed 23 Jan. 2019] (online) Available from:
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Imatinib. [Updated 2018 Oct 31]. [Accessed 18 Feb. 2020] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 26 Mar. 2019] (online) Available from:
- Natco Pharma Limited. Safety Data Sheet: Imatinib Mesylate. 2019. [Accessed 05 Jul. 2023]. (online) Available from:
Marketer details
Name: Novartis India Ltd
Address: Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India
Country of origin: Germany
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₹675
Inclusive of all taxes
MRP₹732.3 8% OFF
10.0 tablets in 1 strip
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