Gleefen 20mg Tablet ER

Baclofen (20mg)

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Gleefen 20mg Tablet ER is a muscle relaxer. It is used to treat muscular symptoms such as rigidity, tension, and stiffness that may occur due to various conditions such as cerebral palsy, multiple sclerosis, motor neuron disease, or injury to the head, brain, or spine.

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 08 Jan 2026 | 11:41 AM (IST)

₹227 MRP ₹256.8812% off

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Baclofen (20mg)

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General Information

Contains

Baclofen (20mg)

Marketer

Sigmund Promedica

Storage

Store below 30°C

The content is shown in English

Product introduction

Gleefen 20mg Tablet ER can be taken with food. In general, you should try to use the smallest amount necessary to control your symptoms, for the shortest possible time. You should take this medicine regularly while you need it. Try not to miss doses as this will make the medicine less effective.

Some common side effects of this medicine include fatigue, weakness, drowsiness, and dizziness. If any of these side effects do not go away or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.

To make sure it is safe for you, before taking this medicine, let your doctor know if you have any medical conditions or disorders. You should also tell your doctor all the other medicines you are using or taking. Pregnant and breastfeeding women should consult their doctors before using this medicine.

Uses of Gleefen Tablet ER

Muscle relaxation

Benefits of Gleefen Tablet ER

Muscle relaxation
Gleefen 20mg Tablet ER is a muscle relaxant that is used to relieve rigidity, inflammation, and swelling in conditions that affect skeletal muscles. It works by blocking chemical messengers in the brain that are responsible for such symptoms. It effectively relieves muscle stiffness or spasm, thereby improving muscle movement.

Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Side effects of Gleefen Tablet ER

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Gleefen

Dizziness

How to use Gleefen Tablet ER

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Gleefen 20mg Tablet ER should be taken with or after food.

How Gleefen Tablet ER works

Gleefen 20mg Tablet ER is a muscle relaxant. It works on the brain and spinal cord to relieve muscle stiffness or spasm maintaining the strength of the muscles. This relieves pain and improves movement of muscles.

All substitutes for Gleefen 20mg Tablet ER

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Gleefen 20mg Tablet ER provides relief from rigidity, tension and stiffness in muscles (spasticity) that may occur due to various conditions affecting the nervous system.
Gleefen 20mg Tablet ER should be taken during meals with a little liquid.
Gleefen 20mg Tablet ER may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
Avoid consuming alcohol when taking Gleefen 20mg Tablet ER as it may cause excessive drowsiness.
Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
Do not stop taking it suddenly without talking to your doctor if you've been on it for a long time.
Gleefen 20mg Tablet ER provides relief from rigidity, tension and stiffness in muscles (spasticity) that may occur due to various conditions affecting the nervous system.
Take it with or after food or a glass of milk.
Gleefen 20mg Tablet ER may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
Avoid consuming alcohol when taking Gleefen 20mg Tablet ER as it may cause excessive drowsiness.
Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
Do not stop taking it suddenly without talking to your doctor if you've been on it for a long time.

Safety advice

Alcohol

CAUTION

Alcohol should be used with caution while taking Gleefen 20mg Tablet ER.

Pregnancy

CONSULT YOUR DOCTOR

Gleefen 20mg Tablet ER is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Gleefen 20mg Tablet ER may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Gleefen 20mg Tablet ER may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Gleefen 20mg Tablet ER should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Gleefen 20mg Tablet ER should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Gleefen with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Tramadol (Injection Route)

If concurrent use is essential, your doctor may monitor your respiratory and cardiovascular functions along with your overall treatment and adjust the doses as per the observations.

Moderate

Trihexyphenidyl (Injection Route)

Talk to your doctor if you notice any unusual symptoms.

Moderate

Alfuzosin (Oral Route)

If concurrent use is essential, watch out for symptoms such as dizziness, fainting, blurred vision, nausea, fatigue, confusion, cold or clammy skin, shallow breathing or rapid pulse and consult your doctor if you experience them. They may adjust the doses as per the observations.

Moderate

Amlodipine (Oral Route)

Moderate

Atenolol (Oral Route)

Frequently asked questions

Can Gleefen 20mg Tablet ER make you sleepy?

Yes, Gleefen 20mg Tablet ER can cause sleepiness. It can make a person dizzy due to its sedative effect. It can also affect vision and therefore you should avoid driving and using heavy machinery until and unless you know how Gleefen 20mg Tablet ER affects you.

Does Gleefen 20mg Tablet ER help anxiety?

Though Gleefen 20mg Tablet ER is not approved to treat anxiety disorders, it has been observed in some studies that it is effective in treating stress which occurs after a trauma.

Can I take Gleefen 20mg Tablet ER if I have a liver problem?

If you have a liver problem then you need to be cautious while taking Gleefen 20mg Tablet ER. This is because the medicine may increase the production of liver enzymes. Hence, regular laboratory examination of liver enzymes is required while taking this medicine as advised by your doctor.

Does Gleefen 20mg Tablet ER have any effect on kidneys?

Gleefen 20mg Tablet ER may cause side effects in patients with normal kidney function which include excessive day time urination (pollakiuria), burning sensation while urinating (dysuria), and loss of bladder control (urinary incontinence). Generally, a lower dose of this medicine is prescribed if a person has abnormally functioning kidneys or if a person is on dialysis.

How should Gleefen 20mg Tablet ER be taken?

Take Gleefen 20mg Tablet ER exactly as directed by your doctor. If a person experiences nausea while taking Gleefen 20mg Tablet ER then it should be consumed with food or milk. However, for night cramps, it would be best to use the medicine at night time or 1 hour before doing specific tasks like physiotherapy or washing.

Fact Box

Chemical Class

Gamma Amino Acids Derivative

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Action Class

Centrally Acting Skeletal Muscle Relaxants

References

White PF, Katzung BG. Skeletal Muscle Relaxants. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 463.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 121-23.
Baclofen. Camberley, Surrey: Novartis Pharmaceuticals UK Ltd.; 2001 [revised 22 Dec. 2017]. [Accessed 23 Jan. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 02 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:
Baclofen [Package Leaflet]. Basel, Switzerland: Novartis Pharma AG; 2021. [Accessed 09 Jun, 2023] (online) Available from:
Baclofen. Athens, GA: Metacel Pharmaceuticals, LLC; 2019. [Accessed 08 Jan, 2026] (online). Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Sigmund Promedica
Address: 30-22-118, First Floor, Eluru Road,Seetharampuram,Vijayawada 520 002,Andhra Pradesh

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Gleefen 20mg Tablet ER

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Gleefen Tablet ER

Benefits of Gleefen Tablet ER

Side effects of Gleefen Tablet ER

How to use Gleefen Tablet ER

How Gleefen Tablet ER works

All substitutes for Gleefen 20mg Tablet ER

Bizlo OD Tablet ER

Baclof OD 20 Tablet ER

Bacrite 20 XR Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Tramadol (Injection Route)

Trihexyphenidyl (Injection Route)

Alfuzosin (Oral Route)

Amlodipine (Oral Route)

Atenolol (Oral Route)

Frequently asked questions

Can Gleefen 20mg Tablet ER make you sleepy?

Does Gleefen 20mg Tablet ER help anxiety?

Can I take Gleefen 20mg Tablet ER if I have a liver problem?

Does Gleefen 20mg Tablet ER have any effect on kidneys?

How should Gleefen 20mg Tablet ER be taken?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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