Gendon Oral Drops is a medicine given to children to help treat nausea and vomiting. It is mainly given to treat nausea and vomiting associated with surgery, chemotherapy, radiotherapy, and stomach/intestinal infection. It also helps treat vomiting that is caused as a side effect of medicines like painkillers.
Gendon Oral Drops may be given before or after meals. To control vomiting caused due to chemotherapy, give this medicine to your child 30 minutes before the procedure. Give it 1 to 2 hours before a radiotherapy session and 1 hour before surgery to prevent your child from vomiting post these procedures. If your child expels out the medicine within 30 minutes of the intake, help your child calm down and repeat the dose. Do not double the dose if it is already time for the next dose.
Gendon Oral Drops may cause some temporary side effects such as headache, constipation, diarrhea, and fatigue. These side effects usually subside once your child’s body adapts to the medicine. In case these side effects persist or become bothersome, do reach out to the doctor on a priority basis.
Let the doctor know about all the medicines your child is taking, including painkillers, antibiotics, or medicines taken to treat depression. Also, inform the doctor if your child has a history of liver problems, kidney malfunction, blockage in the gastrointestinal tract, heart problems, or allergies to any medicine, its ingredients, or a food product. This information is very important for dose alterations and for planning your child’s overall treatment.
Chemotherapy, radiotherapy, major surgeries, and abdominal infection put your child at risk of developing severe nausea and vomiting. It happens due to the release of a chemical called serotonin. Gendon Oral Drops acts by blocking the effect of this chemical and prevents nausea and vomiting. It also helps your child to recover more comfortably from these treatments. Stick to the prescribed dose, time, and way, and do not increase or decrease the dose by yourself without consulting your child’s doctor as it may result in side effects.
Side effects of Gendon Oral Drops
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Gendon
Headache
Constipation
Diarrhea
Fatigue
How to use Gendon Oral Drops
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a marked dropper and take it as directed. Gendon Oral Drops may be taken with or without food, but it is better to take it at a fixed time.
How Gendon Oral Drops works
During radiotherapy, chemotherapy, abdominal infection, or any major surgeries, the dead cells in the body start releasing a chemical called serotonin directly into the blood. Later, this stimulates special centers in the body that are responsible for inducing vomiting in your child. Giving Gendon Oral Drops just before the procedure helps block the effect of this chemical on vomiting centers of the brain and prevents vomiting.
Safety advice
Alcohol
CAUTION
Caution is advised when consuming alcohol with Gendon Oral Drops. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Gendon Oral Drops during pregnancy is not available. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Gendon Oral Drops during breastfeeding is not available. Please consult your doctor.
Driving
CONSULT YOUR DOCTOR
It is not known whether Gendon Oral Drops alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Gendon Oral Drops is safe to use in patients with kidney disease. No dose adjustment of Gendon Oral Drops is recommended.
Liver
CAUTION
Gendon Oral Drops should be used with caution in patients with liver disease. Dose adjustment of Gendon Oral Drops may be needed. Please consult your doctor.
What if you forget to take Gendon Oral Drops?
Do not panic. Give the missed dose as soon as you remember. However, you must skip the missed dose if it’s almost time for the next dose. Do not give a double dose and follow the prescribed dosing schedule.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Monitor temperature of Patient. If Patient has fever place a cool, damp washcloth on your child's forehead. Give your Patient a lukewarm tub bath or a sponge bath. Give a sponge bath as follows: - ? Use lukewarm water [90?F (32.2?C) to 95?F (35?C)]. Do not use cold water, ice, or rubbing alcohol, which will lower the child's body temperature too quickly. ? Sponge for 20 to 30 minutes. ? Stop if the child starts to shiver. If your child doesn't like the sponge bath or doesn't feel better after the bath, there is no need to give another one. You can use paracetamol also along with above measures to control fever till you consult Dr. will determine underlying disorders by clinical examination which range from mild conditions to the most serious of bacterial and viral illnesses and will prescribe medicines accordingly. Advice given without doing clinical examination can be imperfect or some time harmful to patient.
Gendon Oral Drops is generally given before any major surgery or before chemotherapy and radiotherapy sessions. In case your child is about to undergo any of the above procedures, your child’s doctor may ask you to give Gendon Oral Drops to your child to prevent vomiting post-procedure. Apart from this, Gendon Oral Drops is also found useful in treating vomiting caused due to diseases of the stomach. In such a case, your child’s doctor may prescribe giving Gendon Oral Drops to your child for a few days. Stick to the dose for best results.
Q. What if my child takes too much Gendon Oral Drops?
Gendon Oral Drops is unlikely to cause harm if you give an extra dose by mistake. However, you must still speak to your child’s doctor immediately. Sometimes, excessive intake of Gendon Oral Drops can cause some serious side effects like excess sleepiness, agitation, rapid heartbeat, hypertension, flushing, dilated pupils, sweating, involuntary muscle jerk, uncontrolled eye movements, overactive reflexes, and seizures. These symptoms are collectively known as serotonin syndrome. If any of these appear, consult the doctor without any delay.
Q. How should Gendon Oral Drops be stored?
Gendon Oral Drops should be stored at room temperature, in a dry place, away from direct heat and light. Also, keep all the medicines out of the reach and sight of children to avoid any accidental intake.
Q. What all medicines should my child avoid while taking Gendon Oral Drops?
Usually, it is advised not to give Gendon Oral Drops along with antidepressant medicines, apomorphine, anti-migraine medicines, painkillers, heart medicines, and antibiotics like linezolid. But, it is ideal to speak to your child’s doctor before coming to any conclusion. So, narrate your child’s complete medical history to your child’s doctor and follow their advice strictly.
Q. In what conditions do I need to call my child’s doctor right away?
Call your child’s doctor immediately if your child develops symptoms of serotonin syndrome like irregular heartbeat, green-colored vomiting, inability to pass wind, pale skin and eyes, dark-colored urine, restlessness, and insomnia.
Q. My child is having a migraine and is on medication. Can I give Gendon Oral Drops along with it?
Avoid combining Gendon Oral Drops with such medicines because concomitant use of Gendon Oral Drops with medicines meant to treat depression or migraine results in serotonin syndrome. Consult your child’s doctor before giving any medicine to your child.
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References
Ondansetron hydrochloride [FDA Label]. Research Triangle Park, NC: GlaxoSmithKline; 2016. [Accessed 04 Jan. 2020] (online) Available from:
Children’s Minnesota. Patient & Family Education Materials: Ondansetron (Zofran). [Accessed 04 Jan. 2020] (online) Available from:
Ondansetron [Package leaflet: Information for the user]. Harefield, UK: Norgine Pharmaceuticals Limited; 2023. [Accessed 25 Jul. 2024] (online) Available from:
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