Flutamide 250mg Tablet

Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS

Last updated on 07 Apr 2026 | 03:01 PM (IST)

Flutamide 250mg Tablet is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It works by blocking the effects of male hormones such as testosterone.

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General Information

Contains

Flutamide (250mg)

Marketer

Cipla Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Flutamide 250mg Tablet should be taken with or without food, preferably at a fixed time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Breast enlargement in males, sleepiness, nausea, and vomiting are some very common side effects of this medicine. Other than this, yellowing of the skin, loss of appetite, shortness of breath, abdominal pain, dark urine, and skin rashes are some side effects that require immediate action. Regular blood tests are required to check your blood cells along with liver function during treatment with this medicine. It makes your skin more sensitive towards sunlight, hence take extra caution while going out.

Before taking it, tell your doctor if have diabetes, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You may be asked for regular monitoring of blood glucose levels while on treatment.

Uses of Flutamide Tablet

Prostate cancer

Benefits of Flutamide Tablet

Prostate cancer
Prostate cancer is a type of cancer that affects the prostate gland in men and can lead to symptoms like difficulty urinating, pelvic discomfort, or bone pain if it spreads. Flutamide 250mg Tablet helps slow the growth and spread of cancer cells, easing symptoms and improving response to other therapies. It supports better disease control, enhances comfort, and contributes to an improved quality of life during cancer management.

Side effects of Flutamide Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Flutamide

Breast enlargement in male
Sleepiness
Nausea
Abdominal pain
Anemia (low number of red blood cells)
Breast tenderness
Constipation
Decreased appetite
Decreased libido
Depression
Dizziness
Indigestion
Flatulence
Hot flashes
Increased liver enzymes
Rash
Weakness
Weight gain
Vomiting

How to use Flutamide Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Flutamide 250mg Tablet may be taken with or without food.

How Flutamide Tablet works

Flutamide 250mg Tablet blocks the effect of the natural male hormones on the growth of prostate cells. Flutamide 250mg Tablet also blocks the undesired effects of androgens in females such as excessive hair growth and acne.

Quick tips

You have been prescribed Flutamide 250mg Tablet for the treatment of prostate cancer.
Take it with or without food, preferably at the same time every day.
Do not drive or do anything requiring concentration unless you know how Flutamide 250mg Tablet affects you.
It may cause your skin to become light sensitive. Avoid direct exposure to excessive sunlight and use sunscreen when outdoors.
If you are diabetic, monitor your blood glucose regularly while taking Flutamide 250mg Tablet.
Your doctor may want you to have regular blood tests to monitor your liver function while you are taking this medicine. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
Do not stop taking the medication without talking to your doctor first.

Safety advice

Alcohol

CAUTION

Alcohol should be used with caution while taking Flutamide 250mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Flutamide 250mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Flutamide 250mg Tablet during breastfeeding is not available. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Flutamide 250mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of Flutamide 250mg Tablet in patients with kidney disease. Please consult your doctor.

Liver

CAUTION

Flutamide 250mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
"You should not take EUFLEX tablets if you have liver problems or if you are allergic to it. Women should not take EUFLEX tablets. https://hemonc.org/docs/packageinsert/flutamide.pdf

Interaction with drugs

Taking Flutamide with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Loperamide (Oral Route)

Your doctor may monitor your ECG regularly, especially if you are older or female, have heart disease, or have low blood potassium levels.

Moderate

Venlafaxine (Oral Route)

Your doctor may monitor your ECG regularly, especially if you are older or female, have heart disease, or have low blood potassium levels.

Moderate

Aripiprazole (Oral Route)

Your doctor may monitor your ECG regularly, especially if you are older or female, have heart disease, or have low blood potassium levels.

Moderate

Aminophylline (Oral Route)

Your doctor may monitor your potassium levels closely.

Moderate

Voriconazole (Oral Route)

Your doctor may monitor your ECG regularly, especially if you are older or female, have heart disease, or have low blood potassium levels.

Frequently asked questions

Does flutamide lower testosterone?

Yes, flutamide lowers testosterone levels and blocks testosterone from reaching the cancer cells, thereby slowing the growth and of cancer cells.

Fact Box

Chemical Class

Trifluoromethylbenzenes

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Androgen Receptor Antagonists

Related lab tests

Prostate Specific Antigen (Free) PSA

Prostate Specific Antigen (Total) PSA

References

Chrousos GP. The Gonadal Hormones & Inhibitors. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 724.
Flutamide. Kenilworth, New Jersey: Schering Corporation; 2000. [Accessed 27 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
Flutamide. Potters Bar: Generics [UK] Ltd t/a Mylan; 22 Dec. 1997 [revised 4 May. 2015]. [Accessed] (online) Available from:

User feedback

Patients taking Flutamide 250mg Tablet

Twice A Day

44%

Thrice A Day

25%

Once A Day

25%

Twice A Week

What are you using Flutamide Tablet for?

Others

100%

How much was the improvement?

Poor

67%

Average

33%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Cipla Ltd
Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Flutamide 250mg Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Flutamide Tablet

Benefits of Flutamide Tablet

Side effects of Flutamide Tablet

How to use Flutamide Tablet

How Flutamide Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Loperamide (Oral Route)

Venlafaxine (Oral Route)

Aripiprazole (Oral Route)

Aminophylline (Oral Route)

Voriconazole (Oral Route)

Frequently asked questions

Does flutamide lower testosterone?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Prostate Specific Antigen (Free) PSA

Prostate Specific Antigen (Total) PSA

References

User feedback

Patients taking Flutamide 250mg Tablet

What are you using Flutamide Tablet for?

How much was the improvement?

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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