Exalbic 500mcg Tablet

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 23 Mar 2026 | 05:35 PM (IST)

Exalbic 500mcg Tablet is used to prevent chronic obstructive pulmonary disease(COPD), group of lung disorders in which the flow of air to the lungs is blocked and chronic bronchitis. It works by opening the airways and makes breathing easier.

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Exalbic 500mcg Tablet

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Roflumilast (500mcg)

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General Information

Contains

Roflumilast (500mcg)

Marketer

Alembic Pharmaceuticals Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Exalbic 500mcg Tablet can be taken with or without food, but take it at the same time every day to get the most benefit. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you. Do not miss even a single dose, if in any case, you missed a dose, take it as soon as you remember or better to skip the missed dose and continue with regular dosing. It does not prevent the already started breathing trouble or COPD, hence always carry your medical inhaler with you for an emergency.

The most common side effects of this medicine include headache, weight loss, dizziness, insomnia, and back pain. If these bother you, or appear serious, let your doctor know. There may be ways of reducing or preventing them. To overcome dizziness, you must avoid driving and attention-seeking activity until you do not know how medicine affects you. If you experienced sudden weight loss, then regular weight monitoring is required.

Before taking this medicine, let your doctor if you suffer from depression, or suicidal thoughts, or if you have HIV, multiple sclerosis. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. You must inform your doctor if you are pregnant or breastfeeding before treatment.

Uses of Exalbic Tablet

Treatment of Chronic obstructive pulmonary disease (COPD)

Benefits of Exalbic Tablet

Treatment of Chronic obstructive pulmonary disease (COPD)
Chronic Obstructive Pulmonary Disease (COPD) is a progressive lung condition that causes breathing difficulties, frequent coughing, and flare-ups. Exalbic 500mcg Tablet is used to help reduce inflammation in the lungs and lower the risk of COPD exacerbations. It helps improve lung function, decreases the frequency of flare-ups, and supports easier breathing, contributing to better daily activity levels and quality of life.

Side effects of Exalbic Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Exalbic

Weight loss
Dizziness
Insomnia (difficulty in sleeping)
Back pain
Nausea
Diarrhea
Decreased appetite
Headache
Influenza

How to use Exalbic Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Exalbic 500mcg Tablet may be taken with or without food.

How Exalbic Tablet works

Exalbic 500mcg Tablet works by blocking an enzyme in the lungs called phosphodiesterase-4 (PDE4). This helps reduce inflammation and swelling in the airways, making it easier to breathe. It keeps the airways open and prevents flare-ups, and it helps control symptoms of long-term lung disease like COPD.

All substitutes for Exalbic 500mcg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Rofaday Tablet

by Lupin Ltd

₹24.4/tablet

89% costlier

Rofum Tablet

by MSN Laboratories

₹14.9/tablet

16% costlier

Quick tips

Exalbic 500mcg Tablet is used to treat chronic obstructive pulmonary disease (COPD).
It should not be used for sudden attacks of breathlessness (acute bronchospasm).
Consult your doctor if you experience unexplained and significant weight loss while on treatment.
Avoid smoking and minimise your exposure to pollution, dust, and fumes. Along with that, a little exercise each day can help you stay strong.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Exalbic 500mcg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Exalbic 500mcg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Exalbic 500mcg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

SAFE

Exalbic 500mcg Tablet does not usually affect your ability to drive.

Kidney

SAFE IF PRESCRIBED

Exalbic 500mcg Tablet is safe to use in patients with kidney disease. No dose adjustment is recommended.

Liver

UNSAFE

Exalbic 500mcg Tablet is unsafe to use in patients with liver disease and should be avoided.
Use of Exalbic 500mcg Tablet is not recommended in patients with moderate to severe liver disease.

Interaction with drugs

Taking Exalbic with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Aminophylline (Oral Route)

Talk to your doctor if you notice any unusual symptoms.Doctor may monitor your blood sugar level. Aminophylline may reduce blood levels of the active form of Roflumilast.

Moderate

Aminophylline (Injection Route)

Talk to your doctor if you notice any unusual symptoms.Doctor may monitor your blood sugar level. Aminophylline may reduce blood levels of the active form of Roflumilast.

Moderate

Carbamazepine (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Carbamazepine may reduce blood levels and efficacy of Roflumilast.

Moderate

Cimetidine (Oral Route)

Talk to your doctor if you notice any unusual symptoms.Doctor may monitor your liver function. Cimetidine may reduce blood levels of Roflumilast and its active form.

Moderate

Ciprofloxacin (Oral Route)

Watch out for symptoms such as diarrhea, nausea or headaches and consult your doctor if you experience them. They may adjust the dose of Roflumilast accordingly. Ciprofloxacin may raise blood levels of Roflumilast.

Frequently asked questions

Is Exalbic 500mcg Tablet a methylxanthine?

No. Exalbic 500mcg Tablet is not a methylxanthine and works via a different mechanism of action

Is Exalbic 500mcg Tablet available in India?

Yes. Exalbic 500mcg Tablet is available in India in the form of 500 mcg tablet

Is Exalbic 500mcg Tablet a steroid/ narcotic?

No. Exalbic 500mcg Tablet belongs to a class of drugs called phosphodiesterase inhibitors. It does not have a chemical structure or effects similar to steroids. It does not induce sleep and is not a narcotic drug

What is Exalbic 500mcg Tablet used for?

Exalbic 500mcg Tablet is used as a maintenance treatment for severe chronic obstructive pulmonary disease (COPD; a group of lung disorders in which the flow of air to the lungs is blocked) in patients with frequent worsening of COPD symptoms (COPD exacerbations) and with long-term inflammation of airways (chronic bronchitis)

How does Exalbic 500mcg Tablet work?

Exalbic 500mcg Tablet is used to prevent worsening of symptoms in patients with severe chronic obstructive pulmonary disease (COPD; a group of lung disorders in which the flow of air to the lungs is blocked) and long-term inflammation of airways (chronic bronchitis)

How long does Exalbic 500mcg Tablet take to work?

Exalbic 500mcg Tablet may need to be taken for several weeks to achieve its effects and may vary upon individual response. Please follow advice of your doctor regarding dose and duration.

Fact Box

Chemical Class

Benzamide derivative

Habit Forming

Therapeutic Class

RESPIRATORY

Action Class

Phosphodiesterase-IV Inhibitors (COPD)

References

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1232.
ScienceDirect. Roflumilast. [Accessed 01 Apr. 2019] (online) Available from:
Roflumilast. Oranienburg Germany: Takeda GmbH; 2011 [revised Aug. 2018]. [Accessed 28 Jan. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 01 Apr. 2019] (online) Available from:
Roflumilast. Prescribing Information. Novadoz Pharmaceuticals LLC.; 2024. [Accessed 10 Sep. 2025] (online) Available from:
Roflumilast. Piscataway, NJ: Novadoz Pharmaceuticals LLC.; [Accessed 06 Nov. 2025] (online). Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Alembic Pharmaceuticals Ltd
Address: Alembic Road, Vadodara - 390 003, Gujarat,INDIA

Vendor Details

Country of origin: India

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Why we need a prescription?

Exalbic 500mcg Tablet

Save more with additional offers

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Exalbic Tablet

Benefits of Exalbic Tablet

Side effects of Exalbic Tablet

How to use Exalbic Tablet

How Exalbic Tablet works

All substitutes for Exalbic 500mcg Tablet

Rofaday Tablet

Rofum Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Aminophylline (Oral Route)

Aminophylline (Injection Route)

Carbamazepine (Oral Route)

Cimetidine (Oral Route)

Ciprofloxacin (Oral Route)

Frequently asked questions

Is Exalbic 500mcg Tablet a methylxanthine?

Is Exalbic 500mcg Tablet available in India?

Is Exalbic 500mcg Tablet a steroid/ narcotic?

What is Exalbic 500mcg Tablet used for?

How does Exalbic 500mcg Tablet work?

How long does Exalbic 500mcg Tablet take to work?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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