Esponol 1% Injection

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 01 Feb 2026 | 09:46 PM (IST)

Esponol 1% Injection is a general anesthetic. It is used in major surgical procedures. It allows the procedures to be carried out without pain and distress. This injection is used in a hospital setting only.

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General Information

Contains

Propofol (1%)

Marketer

Celon Laboratories Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Esponol 1% Injection causes loss of consciousness which is reversible. It is administered under the supervision of a doctor or a nurse. U=You should not self-administer this medicine at home.

The most common side effects include headache, vomiting, and nausea. This Esponol 1% Injection is safe to use in pregnancy, breastfeeding mothers, patients of liver and kidney disease. Inform your doctor if you are on any medications or have any known allergy to this medicine before the start of the procedure.

It is not advised to consume alcohol after you have been administered. Driving should not be done as this medicine may cause sleepiness and may impair your ability to think or react. It is also advised not to operate machinery because of these effects.

Uses of Esponol Injection

General Anaesthesia

Benefits of Esponol Injection

General Anaesthesia
Esponol 1% Injection is used as a general anaesthesia to help patients fall asleep quickly and comfortably before surgery or medical procedures. It provides a smooth induction and recovery, ensuring a controlled and safe anaesthetic experience.

Side effects of Esponol Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Esponol

Nausea
Headache
Vomiting
Local site pain
Slow heart rate
Decreased blood pressure

How to use Esponol Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Esponol Injection works

Esponol 1% Injection is a general anaesthetic. It works by causing reversible loss of consciousness. This allows surgical procedures to be carried out without pain and distress.

Quick tips

Esponol 1% Injection helps induce unconsciousness (sleep) so that surgical operations or other procedures can be performed.
It is given to you as an injection by your doctor.
After use, you may still feel sleepy for some time. Do not drive or do anything that requires focus until you are sure the effects have subsided.
Inform your doctor if you are pregnant, planning to conceive or breastfeeding.

Safety advice

Alcohol

UNSAFE

Do not drink alcohol while you are taking this medicine. Esponol 1% Injection may cause excessive drowsiness when taken with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Esponol 1% Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CAUTION

Esponol 1% Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

UNSAFE

Esponol 1% Injection may cause side effects that could affect your ability to drive.

Kidney

SAFE IF PRESCRIBED

Esponol 1% Injection is safe to use in patients with kidney disease. No dose adjustment is recommended.
However, talk to your doctor if you have any underlying kidney disease. Use of Esponol 1% Injection can cause green discoloration of urine.

Liver

CAUTION

Esponol 1% Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Esponol with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Sodium Valproate (Oral Route)

If concurrent use is essential, watch out for symptoms such as dizziness, nausea, headache, pain at the injection site, confusion, muscle twitching, cough, dry mouth, changes in taste or itchiness and consult your doctor if you experience them. They may adjust the doses as per the observations. Sodium Valproate may increase the effect of Propofol.

Moderate

Adrenaline (Injection Route)

Talk to your doctor if you notice any unusual symptoms. Adrenaline may increase the side effects of Propofol.

Moderate

Alfuzosin (Oral Route)

Your doctor may discontinue Alfuzosin 24 hours before the surgery.

Moderate

Baclofen (Injection Route)

Talk to your doctor if you notice any unusual symptoms.Avoid activities like driving, lifting weight.

Moderate

Baclofen (Oral Route)

Talk to your doctor if you notice any unusual symptoms.Avoid activities like driving, lifting weight.

Frequently asked questions

What is Esponol 1% Injection used for?

Esponol 1% Injection is an anesthetic medicine used to help you relax, become sleepy, or go to sleep before and during a medical procedure or surgery. It can be used to start general anesthesia or to keep you sedated and comfortable for shorter procedures.

Who will be giving me Esponol 1% Injection?

Esponol 1% Injection will only be given by, or under the direct supervision of, a doctor, or other professionals trained in administering anesthesia, such as an anesthesiologist, or a critical care specialist. They will continuously monitor you throughout the entire process.

How quickly does Esponol 1% Injection work?

Esponol 1% Injection works very quickly, usually making you feel its effects within about 40 seconds of the injection starting. This rapid onset is why it is commonly used to begin anesthesia.

How long will I be asleep from Esponol 1% Injection?

The duration of action from a single Esponol 1% Injection dose is quite short, typically lasting for about 10 to 20 minutes. For longer procedures, it will be given as a continuous infusion to maintain the level of sedation or anesthesia needed.

Will I remember anything from the procedure after being sedated with Esponol 1% Injection?

It is very unlikely that you will remember the surgery or procedure. One of the effects of Esponol 1% Injection is amnesia, which means you will not form memories during the time the medicine is active.

Is the dose of Esponol 1% Injection the same for everyone?

No. The Esponol 1% Injection dose is highly individualized. The anesthesiologist will carefully calculate the right amount for you based on your age, weight, medical condition, and the type of procedure you are having.

Will I feel any pain when Esponol 1% Injection is given?

Some people experience a brief stinging or burning sensation at the IV site when Esponol 1% Injection is first injected. Your anesthesiologist may use techniques to minimize this discomfort, such as giving it through a larger vein or mixing it with a local anesthetic.

Fact Box

Chemical Class

Cumenes

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Action Class

General Anesthetics

References

Patel PM, Patel HH, Roth DM. General Anesthetics and Therapeutic Gases. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 536-37.
White PF, Trevor AJ. General Anesthetics. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 436-37.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1161-62.
Propofol. Dublin, Ireland: Aspen; 1986 [revised 06 Nov. 2018]. [Accessed 23 Jan. 2019] (online) Available from:
Propofol. Lake Zurich, Illinois: Fresenius Kabi USA, LLC; 2014. [Accessed 05 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 05 Apr. 2019] (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Celon Laboratories Ltd
Address: Plot No 264, Patrika Nagar Madhapur, Hitech City Hyderabad, Telangana India - 500081

Vendor Details

Country of origin: India

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Esponol 1% Injection

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Esponol Injection

Benefits of Esponol Injection

Side effects of Esponol Injection

How to use Esponol Injection

How Esponol Injection works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Sodium Valproate (Oral Route)

Adrenaline (Injection Route)

Alfuzosin (Oral Route)

Baclofen (Injection Route)

Baclofen (Oral Route)

Frequently asked questions

What is Esponol 1% Injection used for?

Who will be giving me Esponol 1% Injection?

How quickly does Esponol 1% Injection work?

How long will I be asleep from Esponol 1% Injection?

Will I remember anything from the procedure after being sedated with Esponol 1% Injection?

Is the dose of Esponol 1% Injection the same for everyone?

Will I feel any pain when Esponol 1% Injection is given?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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