Epivir Oral Solution

Lamivudine (10mg)

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Epivir Oral Solution is used in the treatment of HIV infection and chronic hepatitis B virus (HBV) infection. It prevents the multiplication of virus in human cells. This stops the virus from producing new viruses and clears up your infection.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 25 Nov 2025 | 03:05 PM (IST)

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General Information

Contains

Lamivudine (10mg)

Marketer

Glaxo SmithKline Pharmaceuticals Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Epivir Oral Solution is not a cure for HIV or AIDS and only helps to decrease the amount of HIV in your body. This helps to lower your risk of getting HIV-related complications and improves your lifespan. It is prescribed in combination with other HIV medicines. Your doctor will recommend the best medicines for you and will decide the doses that you need. Follow carefully the instructions for all the medicines that you are given. It can be taken with or without food. Taking all these medicines regularly at the right times greatly increases their effectiveness and reduces the chances of HIV becoming resistant to them. It is important not to miss doses and to keep taking them until your doctor tells you it is safe to stop.

Common side effects of this medicine include headache, nausea, vomiting, stomach pain, fatigue, diarrhea, and rash. These are usually not serious but tell your doctor if they bother you or do not go away. Rarely, some people may experience a skin reaction or liver damage. Your doctor will closely monitor you for these in the initial period of treatment.

Before taking it, tell your doctor if you have any skin problems or liver or kidney disease. While using it, you may need regular blood tests to check your blood counts and liver function. Avoid drinking alcohol as it may increase your risk of liver damage. Pregnant or breastfeeding mothers should consult their doctor before using this medicine. Do not have unprotected sex or share personal items like razors or toothbrushes, if you are HIV positive. Talk to your doctor about safe ways like condoms to prevent HIV transmission during sex.

Uses of Epivir Oral Solution

Hepatitis B virus (HBV) infection

Benefits of Epivir Oral Solution

Hepatitis B virus (HBV) infection
In patients with chronic hepatitis B virus (HBV) infection, Epivir Oral Solution works by preventing the HBV virus from multiplying in the body. It helps control the infection and makes the immune system work better. This lowers the chances of getting complications and improves the quality of life. This medicine is always taken in combination with other antiretroviral medicines. It is not a cure and should neither be used to prevent HBV infection. It is important that you take this medicine as prescribed, following the dosage recommended by your doctor. Taking all doses in the right amount at the right times greatly increases the effectiveness of the medicine.

Side effects of Epivir Oral Solution

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Epivir

Nausea
Diarrhea
Headache
Vomiting
Fatigue
Stomach pain
Rash

How to use Epivir Oral Solution

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Epivir Oral Solution may be taken with or without food.

How Epivir Oral Solution works

Epivir Oral Solution is an antiviral medication. It prevents the multiplication of virus in human cells. This stops the virus from producing new viruses and clears up your infection.

Quick tips

You have been prescribed Epivir Oral Solution for the treatment of chronic hepatitis B virus (HBV) infection.
In combination with other medicines, it is used for the treatment of HIV infections.
Take it with food, as this increases the absorption of the medicine into the body.
Epivir Oral Solution may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
You may still develop infections or other illnesses associated with viral infection while taking this medication.
You can also pass on HIV or HBV to others. Don't share needles or personal items that can have blood or body fluids on them.
During treatment and for at least six months after stopping this medicine, regular blood tests are needed to monitor your liver function, level of hepatitis B virus and blood cells in your blood.
You have been prescribed Epivir Oral Solution for the treatment of chronic hepatitis B virus (HBV) infection.
In combination with other medicines, it is used for the treatment of HIV infections.
Take it with food, as this increases the absorption of the medicine into the body.
Epivir Oral Solution may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
You may still develop infections or other illnesses associated with viral infection while taking this medication.
You can also pass on HIV or HBV to others. Don't share needles or personal items that can have blood or body fluids on them.
During treatment and for at least six months after stopping this medicine, regular blood tests are needed to monitor your liver function, level of hepatitis B virus and blood cells in your blood.

Safety advice

Alcohol

CAUTION

Alcohol should be used with caution while taking Epivir Oral Solution.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Epivir Oral Solution during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

SAFE IF PRESCRIBED

Epivir Oral Solution may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Driving

SAFE

Epivir Oral Solution does not usually affect your ability to drive.

Kidney

CAUTION

Epivir Oral Solution should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

SAFE IF PRESCRIBED

Epivir Oral Solution is safe to use in patients with liver disease. No dose adjustment is recommended.

Interaction with drugs

Taking Epivir with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Co-trimoxazole (Oral Route)

Your doctor may monitor your treatment for toxicity of medicines and adjust the doses as per the observations. Co-trimoxazole may slow down the removal of Lamivudine from the body.

Moderate

Ganciclovir (Injection Route)

Do not consume Lamivudine with Ganciclovir. If concurrent use is essential, please consult your doctor. Ganciclovir may reduce blood levels of active form of Lamivudine.

Moderate

Ganciclovir (Oral Route)

Do not consume Lamivudine with Ganciclovir. If concurrent use is essential, please consult your doctor. Ganciclovir may reduce blood levels of active form of Lamivudine.

Moderate

Interferon Alpha 2A (Injection Route)

Your doctor may monitor your treatment and adjust the doses as per the observations.

Moderate

Lactitol (Oral Route)

Do not consume Lamivudine with Lactitol. If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Lactitol may reduce blood levels of Lamivudine.

Frequently asked questions

How should I take Epivir Oral Solution?

Epivir Oral Solution should be taken in the dose and duration advised by the doctor. This medicine can be taken with or without food. However, it is better to take it at a fixed time of the day to avoid the chances of missing a dose.

Is Epivir Oral Solution effective?

Epivir Oral Solution is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Epivir Oral Solution too early, the symptoms may return or worsen.

What is drug resistance? Can I develop drug resistance with Epivir Oral Solution?

Drug resistance is a state where the medicine which was once effective in treating an infection becomes ineffective. This mainly happens due to the ability acquired by the virus or bacteria to get modified inside the body which affects the overall working of the medicine. Hence, the medicine is no longer able to fight against the virus or bacteria. Generally, drug resistance with Epivir Oral Solution is more likely to happen if you take less dose than what is recommended.

How long should I take Epivir Oral Solution?

Do not stop taking entecavir without consulting your doctor. Stopping entecavir before treatment may worsen your hepatitis. This can happen during the first several months after you stop taking entecavir. Take the medicine strictly as advised and do not miss any dose.

What if I forget to take a dose of Epivir Oral Solution?

If you forget a dose of Epivir Oral Solution, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.

What if HIV infection co-exists with HBV infection? Will this affect treatment with Epivir Oral Solution?

In HBV patients who are diagnosed with HIV, Epivir Oral Solution is not recommended until and unless these patients start taking medicines for HIV management. Starting Epivir Oral Solution in such patients may cause resistance to the prescribed HIV medicines. Therefore, doctors recommend tests for HIV in patients diagnosed with HBV infection before starting treatment with Epivir Oral Solution.

Can Epivir Oral Solution cure hepatitis B?

No, Epivir Oral Solution does not cure hepatitis B but may improve the condition of the liver. It may decrease the amount of hepatitis B virus (HBV) present in the body. This is done by limiting the ability of HBV to multiply and further infect new liver cells.

Is Epivir Oral Solution safe?

Epivir Oral Solution is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.

Fact Box

Chemical Class

3'- thia pyrimidine nucleosides

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Action Class

Nucleoside/Nucleotide Reverse Transcriptase Inhibitors (NRTIs)

Related lab tests

Hepatitis B (Core) IgM Antibody

Hepatitis B s (Surface) Antigen

Hepatitis C Virus Total Antibody

References

Acosta EP, Flexner C. Antiviral Agents (Nonretroviral). In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1617-618.
Safrin S. Antiviral Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 858, 869-70.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 767-70.
Lamivudine. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2012 [revised 24 Jun. 2018]. (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 31 Mar. 2019] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Glaxo SmithKline Pharmaceuticals Ltd
Address: Dr. Annie Besant Road, Mumbai - 400 030

Vendor Details

Country of origin: Canada

Lab tests offered by us

Why we need a prescription?

Epivir Oral Solution

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Epivir Oral Solution

Benefits of Epivir Oral Solution

Side effects of Epivir Oral Solution

How to use Epivir Oral Solution

How Epivir Oral Solution works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Co-trimoxazole (Oral Route)

Ganciclovir (Injection Route)

Ganciclovir (Oral Route)

Interferon Alpha 2A (Injection Route)

Lactitol (Oral Route)

Frequently asked questions

How should I take Epivir Oral Solution?

Is Epivir Oral Solution effective?

What is drug resistance? Can I develop drug resistance with Epivir Oral Solution?

How long should I take Epivir Oral Solution?

What if I forget to take a dose of Epivir Oral Solution?

What if HIV infection co-exists with HBV infection? Will this affect treatment with Epivir Oral Solution?

Can Epivir Oral Solution cure hepatitis B?

Is Epivir Oral Solution safe?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Hepatitis B (Core) IgM Antibody

Hepatitis B s (Surface) Antigen

Hepatitis C Virus Total Antibody

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests