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Composition for ENDACE

Megestrol(40 mg)

food interaction for ENDACE

alcohol interaction for ENDACE

pregnancy interaction for ENDACE

lactation interaction for ENDACE

It can be taken with or without food, but it is better to take Endace 40 mg tablet at a fixed time.
Interaction with alcohol is unknown. Please consult your doctor.
Endace 40 mg tablet is highly unsafe in women who are or may become pregnant.
Human and animal studies have shown significant adverse effects on the fetus and should not be given under any circumstances. Please consult your doctor.
Endace 40 mg tablet is probably unsafe to use during breastfeeding. Please consult your doctor.


Megestrol(40 mg)


Endace 40 mg tablet is used to treat certain types of hormone-dependent cancers like breast cancers.

How it works

Endace 40 mg tablet is a progestational agent or a synthetic form of the female sex hormone progesterone. It works by decreasing the estrogen secretion and to some extent by direct cytotoxic effect on tumor cells.

Common side effects

Vomiting, Nausea, Pain in extremity, Excessive thirst, Frequent urge to urinate, Abnormal vaginal bleeding, Acne-like rash, Blurred vision, Decreased sexual function, Dizziness, Shortness of breath, Flatulence, Impotence, Feeling thirsty, Increased appetite, Insomnia, Slow speech, Difficult speech, Weakness, Numbness of extremity, Chest discomfort, Heart rate irregular, Chest pain

Common Dosage

Patients taking this medicines

  • 67%
    Two Times A Day
  • 20%
    Three Times A Day
  • 7%
    Four Times A Day
  • 7%
    One Time A Day


2 Substitutes
Sorted By
    (10 tablets in strip)
    Alkem Laboratories Ltd
    Rs. 21.43/tablet
    Rs. 214.28
    save 24% more per tablet
    (10 tablets in strip)
    Alniche Life Sciences Pvt Ltd
    Rs. 23/tablet
    Rs. 230
    save 19% more per tablet

Expert advice for ENDACE

  • Inform the doctor before taking megestrol if you have a history of thrombophlebitis (blood clots) or a suffering from liver or kidney disease, diabetes or adrenal gland disorder.
  • You should use megestrol with caution if you are an elderly patient as it may cause decreased liver, renal or heart functions.
  • Take precautions as megestrol may interfere with the normal menstrual cycle (period) in women.
  • Seek medical emergency if you develop any allergic reaction like swelling of lips, face and tongue, skin rash, difficulty breathing while taking megestrol.

Frequently asked questions for ENDACE


Q. Is megestrol safe?
Megestrol is safe if it is taken at a particular dose, duration and indication as prescribed by the doctor.
Q. Is megestrol a steroid/ chemo drug?
Megestrol is a steroid and also used in chemotherapy of breast cancer
Q. Is megestrol acetate a controlled substance?
Megestrol is not a controlled substance.
Q. Is megestrol cytotoxic?
Megestrol is a progestational agent or a synthetic form of the female sex hormone progesterone. Its anti-neoplastic effect against breast cancer is exerted by inhibition of pituitary gonadotrophin production (type of hormone released from the pituitary gland) and resultant decrease in estrogen secretion, and to some extent by direct cytotoxic effect on tumor cells.
Q. Does megestrol stop bleeding?
Megestrol stops unusual heavy bleeding from the uterus (dysfunctional uterine bleeding).


Content on this page was last updated on 30 June, 2016, by Dr. Varun Gupta (MD Pharmacology)