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Thyroxine is used in the treatment of hypothyroidism and myxedema coma (disease caused by lack of thyroid hormone in which areas of the skin are swollen)

How it works

Thyroxine is similar in structure to the hormone naturally produced by the thyroid gland. It provides more thyroid hormones and relieves the symptoms of tiredness, weight gain, and depression.

Common side effects

Enlarged thyroid gland, Increased heart rate, Goiter, Insomnia, Altered heart rate, Abdominal pain, Fever, Diarrhoea, Irregular menstrual cycle, Increased blood pressure, Chest pain, Nervousness, Tremor

Available Medicine

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Expert advice

  • Food prevents proper absorption of the drug. Take thyroxine  on an empty stomach half an hour before breakfast. Keep a gap of 4 hours between thyroxine and antiacids, calcium or iron supplements and mulltivitamins.
  • Take special precaution and consult your doctor: If you suffer from diabetes, high blood pressure, heart failure or have had a heart attack, or condition that affects your adrenal glands, If you are over 50 years of age and have a long standing history of hypothyroidism.
  • An electrocardiogram (ECG; test to measure the electrical activity of heart) is advised before starting treatment with levothyroxine, as changes induced by hypothyroidism may be confused with changes that occur due to decreased blood flow to heart (ischemia).

Frequently asked questions



What is thyroxine?
Thyroxine is a hormone that is secreted by the follicular cells of thyroid gland


Is it an amine/ peptide or steroid hormone?
Thyroxine is derived by iodination of tyrosine (amino acid) after biochemical synthesis. Thyroxine is neither a steroid nor amine nor peptide


Is eltroxin/thyronorm/synthroid same?
Yes. Eltroxin, thyronorm and synthroid contain levothyroxine sodium as main ingredient

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Is eltroxin gluten free and still available?
Yes. Eltroxin is gluten free and available in India


Is thyronorm better than eltroxin?
No. Both the drug contain same active ingredient i.e. levothyroxine sodium


Is eltroxin used for hyperthyroidism?
No. It is not used for the treatment of hyperthyroidism. On the contrary, it is used for hypothyroidism


Is eltroxin dangerous?
No. Eltroxin is not dangerous but check with your doctor, if you observe any symptoms of possible side effects


Is thyronorm T3 or T4?
Thyronorm is a synthetic version of the thyroid gland hormone-Thyroxine (T4)


Is thyroxine water soluble or hydrophobic?
Thyroxine is also insoluble in water (hydrophobic) and lipophilic in nature.

Content on this page was last updated on 10 February, 2017, by Dr. Varun Gupta (MD Pharmacology)