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Efficin 1000mg Injection

Kanamycin (1000mg)
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Efficin 1000mg Injection is an antibiotic used to treat a wide variety of bacterial infections. This may include infections of the urinary tract, bones and joints, lungs (eg. pneumonia), blood, and some others. It is also used in the treatment of resistant tuberculosis.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 08 May 2026 | 05:15 PM (IST)
₹34.9 MRP ₹38.6510% off 
 
 
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General Information

The content is shown in English
Efficin 1000mg Injection image
Efficin 1000mg Injection image

Product introduction

Efficin 1000mg Injection works by stopping the growth of bacteria. It is given as a drip (intravenous infusion) or as an injection directly into a vein or a muscle under the supervision of a healthcare professional. It should be used regularly at evenly spaced time intervals as prescribed by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening.

This medicine may lead to hearing loss, balance disorder (loss of balance), injection site pain, and kidney damage as side effects in some patients. Therefore, please follow all the instructions given by your doctor while using this medicine. If these side effects do not resolve or worsen, please consult your doctor.

Your doctor may monitor you with regular kidney function tests, hearing tests, and urine tests during treatment. Some patients may also be advised to get the blood levels of this medicine measured. This medication is not recommended for use during pregnancy. Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.

Uses of Efficin Injection

Benefits of Efficin Injection

Bacterial infections
Efficin 1000mg Injection is used to treat serious bacterial infections by stopping the growth of harmful bacteria. It is effective against a range of severe infections when other treatments may not work.
Tuberculosis (TB)
In tuberculosis, especially drug-resistant TB, Efficin 1000mg Injection is used as part of a combination therapy to help control the infection and prevent its spread, improving treatment success in challenging cases.

Side effects of Efficin Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Efficin
  • Hearing loss
  • Balance disorder (loss of balance)
  • Injection site pain
  • Renal impairment

How to use Efficin Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Efficin Injection works

Efficin 1000mg Injection is an antibiotic. It stops bacterial growth by preventing synthesis of essential proteins required by bacteria to carry out vital functions.

Quick tips

  • Your doctor has prescribed Efficin 1000mg Injection to cure your infection and improve your symptoms.
  • Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection to come back and harder to treat.
  • It is given by an injection into a muscle.
  • Use caution while driving or doing anything that requires concentration as Efficin 1000mg Injection may cause dizziness.
  • Your doctor may get regular blood, urine, or hearing tests while you are on this medication.
  • Your doctor will ensure that you are well hydrated before and during treatment with this medicine. 
  • Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.
  • Discontinue Efficin 1000mg Injection and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Efficin 1000mg Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Efficin 1000mg Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CAUTION
Efficin 1000mg Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Efficin 1000mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CAUTION
Efficin 1000mg Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Efficin 1000mg Injection in patients with liver disease.

Interaction with drugs

Taking Efficin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Vancomycin (Injection Route)

If concurrent use is essential, your doctor may closely monitor your kidney's functioning and overall treatment.
Severe

Carboplatin (Injection Route)

Your doctor may monitor your electrolyte levels, kidney function, and hearing ability along with your overall treatment.
Severe

Magnesium Oxide (Oral Route)

Do not consume Kanamycin with Magnesium Oxide. If essential, individuals with high blood magnesium levels should watch out for breathlessness and immediately consult their doctor if they experience it.
Severe

Tacrolimus (Oral Route)

If concurrent use is essential, your doctor may monitor your tacrolimus levels, potassium levels and kidney function closely. They may adjust the doses as per the observations.
Severe

Colistin Sulphate (Injection Route)

Do not consume Colistin Sulphate with Kanamycin. If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.

Frequently asked questions

The usual course of treatment with Efficin 1000mg Injection is about 7 to 10 days. However, your doctor will decide your dose depending on the condition you are being treated for. Continue taking Efficin 1000mg Injection in the dose and duration prescribed by the doctor to get maximum benefit. Do not alter the dose of the medicine on your own, consult your doctor first.
Efficin 1000mg Injection is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
Efficin 1000mg Injection should be administered under the supervision of a trained healthcare professional or a doctor only and should not be self-administered. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get maximum benefit from Efficin 1000mg Injection.
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Inform your doctor if you don't feel better after finishing the full course of treatment. Also, consult your doctor if your symptoms are getting worse while using this medicine. The doctor may modify the dose or suggest an alternative medicine.
No, do not stop taking Efficin 1000mg Injection without consulting the doctor even if you are feeling better. Your symptoms may improve before the infection is completely cured. Therefore, for better and complete treatment, it is advised to continue your treatment for the prescribed duration.

Fact Box

Chemical Class

4,6- disubstituted 2- deoxystreptamines

Habit Forming

No

Therapeutic Class

ANTI INFECTIVES

Action Class

Bacterial Protein Synthesis Inhibitors- Aminoglycosides

References

  1. MacDougall C, Chambers HF. Aminoglycosides. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1517-18.
  2. Chambers HF, Deck DH. Aminoglycosides & Spectinomycin. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 813.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 755.
  4. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 31 Mar. 2019] (online) Available from:
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 31 Mar. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Lupin Ltd
Address: 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India

Vendor Details

Country of origin: India
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