
Dyclo Injection
Written By Dr. Swati Mishra, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 21 Sep 2025 | 05:27 PM (IST)
Dyclo Injection is a pain-relieving medicine. It is used to treat various types of pain, swelling, stiffness, and joint pain in conditions like rheumatoid arthritis, osteoarthritis, and acute musculoskeletal injuries. It is given in cases where oral administration is not possible.
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Dyclo Injection
ampoule of 1 ml Injection
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ampoule of 1 ml Injection
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General Information
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Product introduction
Dyclo Injection is generally administered by a doctor or a nurse. Do not self-administer this medicine at home. Inform your doctor if you have any history of heart disease or stroke. Consult your doctor in case any injection site reactions like pain, swelling, or redness are observed.
The most common side effects of this medicine include nausea, vomiting, headache, and injection site reactions. Your doctor may regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment. Long-term use may lead to serious complications such as stomach bleeding and kidney problems.
Uses of Dyclo Injection
Benefits of Dyclo Injection
Pain relief
Dyclo Injection belongs to a group of medicines called nonsteroidal anti-inflammatory drugs (NSAIDs). It is used for short-term relief of pain, inflammation, and swelling in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis.
Take it as it is prescribed to get the most benefit. Do not take more or longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.
Dyclo Injection belongs to a group of medicines called nonsteroidal anti-inflammatory drugs (NSAIDs). It is used for short-term relief of pain, inflammation, and swelling in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis.
Take it as it is prescribed to get the most benefit. Do not take more or longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.
Side effects of Dyclo Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Dyclo
- Diarrhea
- Flatulence
- Vomiting
- Headache
- Injection site reactions (pain, swelling, redness)
- Dizziness
- Nausea
- Constipation
- Insomnia (difficulty in sleeping)
- Abdominal pain
- Dyspepsia
- Gastrointestinal bleeding
- Gastrointestinal ulcer
- Rash
- Application site irritation
- Injection site pain
How to use Dyclo Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Dyclo Injection works
Dyclo Injection is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling).
All substitutes for Dyclo Injection
For information purposes only. Consult a doctor before taking any medicine.
Dyact-AQ Injection
by Medixcel Pharmaceuticals Pvt Ltd
₹45/injection
200% costlier
3 Flam Aqua Injection
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₹23.44/injection
56% costlier
Fenozil 75mg Injection
by Lifekyor Pharmaceuticals
₹14.06/injection
6% cheaper
Oxalgin AQ Injection
by Zydus Cadila
₹14.4/injection
4% cheaper
Unidic-AQ Injection
by Unimarck Pharma India Ltd
₹20.63/injection
38% costlier
Quick tips
- You have been prescribed Dyclo Injection to relieve pain and inflammation.
- Long-term use may lead to serious complications such as stomach bleeding and kidney problems.
- It may cause dizziness, drowsiness, or visual disturbances. Use caution while driving or doing anything that requires concentration.
- Avoid consuming alcohol while taking Dyclo Injection as it can cause excessive drowsiness and increase your risk of stomach problems.
- Your doctor may regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment.
Safety advice

Alcohol
CAUTION
Caution is advised when consuming alcohol with Dyclo Injection. Please consult your doctor.

Pregnancy
CONSULT YOUR DOCTOR
Dyclo Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding
CONSULT YOUR DOCTOR
Dyclo Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving
UNSAFE
Dyclo Injection may cause side effects which could affect your ability to drive.

Kidney
CAUTION
Dyclo Injection should be used with caution in patients with kidney disease. Dose adjustment of Dyclo Injection may be needed. Please consult your doctor.

Liver
CAUTION
Dyclo Injection should be used with caution in patients with liver disease. Dose adjustment of Dyclo Injection may be needed. Please consult your doctor.
Interaction with drugs
Taking Dyclo with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe
Fondaparinux (Injection Route)
If concurrent use is essential, watch out for bleeding and consult your doctor immediately.
Severe
Heparin (Injection Route)
Do not consume Diclofenac with Heparin. If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Diclofenac may increase the effect of Heparin.
Severe
Tacrolimus (Oral Route)
If concurrent use is essential, your doctor may monitor your tacrolimus levels, potassium levels and kidney function closely. They may adjust the doses as per the observations.
Severe
Methotrexate (Injection Route)
Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Severe
Methotrexate (Injection Route)
Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Frequently asked questions
Dyclo Injection should only be given by a healthcare professional. It can be given deep into the muscle (intramuscularly), preferably in the buttock, under the skin (subcutaneously), or directly into a vein (intravenously) as a bolus and not as an infusion. The dose should not exceed the prescribed quantity and injection should not be given for more than 2 days.
It is important to know that Dyclo Injection may increase your chance of having a heart attack or stroke. The risk is higher if you take higher doses and have used the medicine for a long time. Additionally, Dyclo Injection may cause ulcers, bleeding, or holes in your stomach and intestine. If you experience any such problems, consult your doctor immediately.
Dyclo Injection is effective in relieving pain and inflammation. It is used for various sorts of pain such as sprains, strains, and other injuries. It is also helpful in various types of arthritis, gout, pain, and inflammation following surgery.
Long-term use and high doses of Dyclo Injection may cause renal problems such as protein or blood in urine and painful urination. Patients who are at maximum risk of developing kidney problems include dehydrated people, individuals with heart failure, impaired kidney function, hypertension, and the elderly. Hence, for such patients kidney function monitoring is recommended.
Dyclo Injection is effective in relieving pain and inflammation. It is used for various sorts of pain such as sprains, strains and other injuries. It is also helpful in various types of arthritis, gout, pain and inflammation following surgery.
No, Dyclo Injection is not a narcotic. It belongs to non-steroidal anti-inflammatory drugs (NSAIDs) group of medicines.
No, Dyclo Injection does not get you high. It does not have an abuse potential (drug-seeking behavior) and does not cause physical or psychological dependence. However, if you do not feel well, consult your doctor.
Long-term use and high doses of Dyclo Injection may cause renal problems such as protein or blood in urine and painful urination. Patients who are at maximum risk of developing kidney problems include people who are dehydrated, have heart failure, impaired kidney function, hypertension, elderly, who are on medicines which cause excess urination (diuretics), or medicines which have significant impact on kidney function. Hence, for such patients kidney function monitoring is recommended.
Dyclo Injection can cause drowsiness and also dizziness, fatigue (tiredness) and visual disturbances. However, it is not very common and may not affect everyone. If you experience these symptoms avoid driving or operating heavy machinery.
It is important to know that Dyclo Injection may increase your chance of having a heart attack or stroke. The risk is more if you take higher doses and have been using the medicine for a longer time. Also, taking Dyclo Injection may cause ulcers, bleeding, or holes in your stomach and intestine. These problems may happen without warning symptoms at any time during treatment and may even cause death. Therefore, if you encounter any such problems, consult your doctor immediately.
You should not take Dyclo Injection during the last 3 months of pregnancy as it may cause harmful effects on your baby. Use of Dyclo Injection can also lead to reduced labor (premature delivery). Hence, it is advised to avoid using Dyclo Injection during the first 6 months of pregnancy also. In some cases, Dyclo Injection may be prescribed in pregnant women only if the benefits outweigh the risks involved with its use in pregnant women. If not sure, consult your doctor regarding its use.
Fact Box
Chemical Class
Phenylacetic acid Derivative
Habit Forming
No
Therapeutic Class
PAIN ANALGESICS
Action Class
NSAID's- Non-Selective COX 1&2 Inhibitors (acetic acid)
References
- Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 626.
- Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 986-87.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 295-97.
- Diclofenac. Dublin 2, Republic of Ireland: Flynn Pharma Ltd.; 2017. [Accessed 02 Apr. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:
- Diclofenac [Prescribing Information]. Lake Forest, IL: Hospira, Inc.; 2014. [Accessed 06 Apr. 2024] (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
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Name: Vitabiotech Healthcare Private Limited
Address: Property No.5 Jajman Complex, Nanhera Road, Kuldeep Nagar, Ambala Cantt(H.R) 133004
Address: Property No.5 Jajman Complex, Nanhera Road, Kuldeep Nagar, Ambala Cantt(H.R) 133004
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