Drunem 250mg Injection

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 31 Mar 2026 | 02:31 PM (IST)

Drunem 250mg Injection is an antibiotic that is used to treat severe infections of the skin, lungs, stomach, urinary tract, blood, and brain (eg. meningitis). It works by killing the bacteria that cause these problems. However, it will not treat a viral infection.

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General Information

Contains

Meropenem (250mg)

Marketer

Drukst Biotech Private Limited

Storage

Store below 30°C

The content is shown in English

Product introduction

Drunem 250mg Injection is commonly used to treat critically ill patients admitted to the hospital. This medicine is given by drip/infusion or by direct injection into a vein, under the supervision of a doctor or a nurse. The dose will depend on what type of infection you have, where it is in the body, and how serious it is. You should keep on taking the injection for as long as you have been prescribed, even if your symptoms quickly improve. If you stop taking it too early the infection may return or worsen.

Some people may develop side effects like headache, nausea, constipation, diarrhea, anemia, vomiting, and rash. These side effects are usually temporary and go away as your body adjusts to the medicine. Consult your doctor if these side effects bother you or do not go away.

Before starting treatment with this medicine, you should tell your doctor if you have epilepsy (seizures), liver or kidney problems or if you are allergic to any antibiotic. While using it, you may be advised blood tests to monitor your blood cell count and kidney function. This medicine is generally regarded as safe to use in pregnancy and breastfeeding if prescribed by the doctor.

Uses of Drunem Injection

Severe bacterial infections

Benefits of Drunem Injection

Severe bacterial infections
Drunem 250mg Injection belongs to a group of medicines called carbapenem antibiotics. It works by killing bacteria which can cause serious infections. It is a versatile medicine used to treat many different types of bacterial infections such as infections of the brain (meningitis), lungs (pneumonia), abdomen, urinary tract, skin, and blood. This medicine is usually given as an injection by a doctor or nurse.

Drunem 250mg Injection usually makes you feel better very quickly but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.

Side effects of Drunem Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Drunem

Vomiting
Nausea
Rash
Injection site inflammation
Sepsis
Apnea (absence of breathing)
Shock
Headache
Itching
Diarrhea
Anemia (low number of red blood cells)
Constipation

How to use Drunem Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Drunem Injection works

Drunem 250mg Injection is an antibiotic. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to survive.

All substitutes for Drunem 250mg Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Drunem 250mg Injection is an antibiotic that's usually only given in the hospital for serious infections.
Inform your doctor if you are allergic to penicillin or if you are taking any seizure medication before starting treatment with this medication.
Diarrhea may occur as a side effect. Inform your doctor if you develop severe stomach pain or if you find blood in your stools.
Your doctor may monitor your kidney function and blood count while you are having treatment with this medication.
Drunem 250mg Injection is an antibiotic that's usually only given in the hospital for serious infections.
It is given by a drip into a vein (intravenous infusion) over 20 to 60 minutes.
Inform your doctor if you are allergic to penicillin or if you are taking any seizure medication before starting treatment with this medication.
Diarrhea may occur as a side effect. Inform your doctor if you develop severe stomach pain or if you find blood in your stools.
Your doctor may monitor your liver and kidney function while you are having treatment with this medication.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Drunem 250mg Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Drunem 250mg Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Drunem 250mg Injection may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Drunem 250mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CAUTION

Drunem 250mg Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Drunem 250mg Injection in patients with liver disease.

Interaction with drugs

Taking Drunem with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Probenecid (Oral Route)

Do not consume Meropenem with Probenecid. If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Probenecid may raise blood levels of Meropenem.

Moderate

Acenocoumarol (Oral Route)

Your doctor may monitor your blood coagulation status and adjust the dose of Acenocoumarol accordingly.

Moderate

Warfarin (Oral Route)

Your doctor may monitor your blood coagulation status and adjust the dose of Warfarin accordingly.

Mild

Risperidone (Oral Route)

Talk to your doctor if you notice any unusual symptoms. Meropenem may raise blood levels of the active form of Risperidone.

Mild

Risperidone (Injection Route)

Talk to your doctor if you notice any unusual symptoms. Meropenem may raise blood levels of the active form of Risperidone.

Frequently asked questions

My friend has a history of epilepsy and she was on valproic acid while receiving treatment with Drunem 250mg Injection, still, she had an episode of seizure. Why?

Any previous history with any other medication should be informed to the doctor before starting your treatment with Drunem 250mg Injection. Medicines like Drunem 250mg Injection can interfere with valproic acid which is used for the treatment of epilepsy, making it less effective. So, the reason for the recent episode of seizure could be the result of such drug interaction. Generally, in cases like these, the doctor prescribes a different medicine.

Even though Drunem 250mg Injection is used for skin infections, can it cause any skin-related problems?

Is Drunem 250mg Injection a strong antibiotic? Which infections does it treat?

Drunem 250mg Injection is a broad-spectrum antibiotic which means it can treat a variety of bacterial infections. It is used to treat infections affecting the lungs (pneumonia) and complicated infections of the urinary tract, abdomen, and skin and soft tissue infections. Along with that, it is also helpful in treating bacterial infection of the membranes that surround the brain and spinal cord (meningitis) and infections that occur during or after delivery.

Is Drunem 250mg Injection effective against bacteria only? Can it be used for any type of bacterial infection?

Yes, Drunem 250mg Injection is effective only against bacteria. It is not effective against virus or fungal infections. Drunem 250mg Injection is effective against some bacteria which include Staphylococcus aureus, Streptococcus pneumoniae, S. pyogenes, S. viridans group, etc. Therefore, its use against any other type of bacteria should be avoided.

My cousin was receiving Drunem 250mg Injection for severe skin infection, but the medicine was stopped when she had a fit. Was the fit due to Drunem 250mg Injection?

There are reports which suggest the occurrence of seizures or fits with the use of Drunem 250mg Injection. However, fits are more likely to occur in patients with a history of seizures or a brain lesion (wound, ulcer, abscess or tumor) or patients having bacterial meningitis or compromised kidney function. Consult your doctor to understand the exact reason.

For how long will I need to take Drunem 250mg Injection?

The length of the treatment will be decided by your doctor. The doctor will decide the dose depending on your general health, the type of infection you have, and how well you respond to Drunem 250mg Injection. Consult your doctor if you are not sure.

What if Drunem 250mg Injection does not suit me?

It is common to have minor side effects such as nausea, vomiting, diarrhea, and headache with the use of Drunem 250mg Injection. However, these symptoms generally settle down with continued medication as the body adapts to the medicine. If the side effects bother you, inform your doctor. The doctor will suggest an alternative medicine if required. Serious side effects with Drunem 250mg Injection are very rare. In case you develop serious side effects, seek immediate medical advice.

Does it matter if I miss or stop Drunem 250mg Injection?

You mustn't stop the treatment without consulting your doctor. Stopping the treatment may bring back the infection or you may develop resistance to Drunem 250mg Injection. Similar results may be seen if you skip any dose or are forgetful in taking the suggested doses. Therefore, it is recommended that you do not miss doses. If you do, take the missed dose as soon as you can and take the next dose as planned so that you stick to the same overall daily dose.

Fact Box

Chemical Class

Thienamycins

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Action Class

Carbapenems

Related lab tests

Complete Blood Count

References

Petri WA Jr. Penicillins, Cephalosporins, and Other β -Lactam Antibiotics. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1500.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 866-67.
Meropenem. Wilmington, DE: AstraZeneca Pharmaceuticals; 1996 [revised Nov. 2013]. [Accessed 29 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:
Meropenem. Mumbai, Maharashtra: Pfizer Ltd.; 2025. [Accessed 19 Jan. 2026]. (online). Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Drukst Biotech Private Limited
Address: C/o Shalini Rastogi W/o Upendra Rastogi Room No. 11, Marwari Hotel, Chowk lucknow UP 226003 IN , - , .

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Drunem 250mg Injection

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Drunem Injection

Benefits of Drunem Injection

Side effects of Drunem Injection

How to use Drunem Injection

How Drunem Injection works

All substitutes for Drunem 250mg Injection

Meromac 250mg Injection

Merotec 250mg Injection

Merosure 250mg Injection

Merocrit 250mg Injection

Merotrol 250mg Injection

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Probenecid (Oral Route)

Acenocoumarol (Oral Route)

Warfarin (Oral Route)

Risperidone (Oral Route)

Risperidone (Injection Route)

Frequently asked questions

My friend has a history of epilepsy and she was on valproic acid while receiving treatment with Drunem 250mg Injection, still, she had an episode of seizure. Why?

Even though Drunem 250mg Injection is used for skin infections, can it cause any skin-related problems?

Is Drunem 250mg Injection a strong antibiotic? Which infections does it treat?

Is Drunem 250mg Injection effective against bacteria only? Can it be used for any type of bacterial infection?

My cousin was receiving Drunem 250mg Injection for severe skin infection, but the medicine was stopped when she had a fit. Was the fit due to Drunem 250mg Injection?

For how long will I need to take Drunem 250mg Injection?

What if Drunem 250mg Injection does not suit me?

Does it matter if I miss or stop Drunem 250mg Injection?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Complete Blood Count

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests