Product introduction
Donil Tablet is used to treat mild to moderate dementia in Alzheimer’s disease, a progressive illness that gradually affects memory and thinking. It does not cure this illness but may help improve memory, awareness, and other symptoms.
Your doctor will explain how to take Donil Tablet. You may take it with food, preferably at night before going to bed. Follow the instructions carefully to get the most benefit. The dose may change from time to time to suit your individual needs. It can take up to a few weeks for symptoms to improve so keep taking your medicine regularly. You should not stop taking this medicine without consulting your doctor.
Some common side effects of this medicine include nausea, diarrhea, insomnia, vomiting, muscle cramps, fatigue, weight loss (anorexia), headache, loss of appetite, common cold, urinary incontinence, and rash. Drink plenty of fluids to keep yourself hydrated. You may have side effects more often when you start your treatment or when your dose is increased. Usually, the side effects will slowly go away as your body gets used to the Donil Tablet. If they are severe or will not go away, you should contact your doctor.
Before using Donil Tablet, you should tell your doctor if you have ever had heart problems, stomach ulcers, epilepsy, or asthma. It may also affect, or be affected by, some other drugs you are using so let your doctor know what these are to be safe. During pregnancy, this medicine should only be taken if it is advised.
Uses of Donil Tablet
Benefits of Donil Tablet
In Alzheimer's disease
Alzheimer’s disease is a common cause of dementia, leading to memory loss, confusion, and difficulty with thinking and daily tasks. Donil Tablet is a medicine used to help manage symptoms of Alzheimer's-related dementia. It works by increasing the levels of a chemical in the brain called acetylcholine, which helps nerve cells communicate better. While it does not cure the disease, It can help improve memory, awareness, and the ability to perform daily activities in some people.
Side effects of Donil Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Donil
- Weight loss
- Common cold
- Urinary incontinence
- Rash
- Nausea
- Diarrhea
- Insomnia (difficulty in sleeping)
- Accidental injury
How to use Donil Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Donil Tablet may be taken with or without food.
How Donil Tablet works
Memory loss in Alzheimer’s disease occurs due to disturbances of signal transmission in the brain. Donil Tablet is a cholinesterase inhibitor. It works by increasing the levels of a chemical messenger (acetylcholine) involved in transmmission of nerve signals. This improves memory and thinking.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Donil Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Donil Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Donil Tablet during breastfeeding is not available. Please consult your doctor.
Driving
CONSULT YOUR DOCTOR
It is not known whether Donil Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney
CAUTION
Donil Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver
CAUTION
Donil Tablet should be used with caution in patients with severe liver disease. Dose adjustment may be needed.
What if you forget to take Donil Tablet?
If you miss a dose of Donil Tablet, skip it and continue with your normal schedule. Do not double the dose.\n
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For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips
- You have been prescribed Donil Tablet to slow down the progression of Alzheimer's disease.
- It does not cure Alzheimer's disease but may help improve brain function and ability to do daily activities.
- Take it with or without food, preferably at night before going to bed.
- It may cause diarrhea, nausea, and vomiting. Drink plenty of fluids to keep yourself hydrated while taking Donil Tablet.
- Monitor your body weight regularly as both Donil Tablet and Alzheimer's disease can cause weight loss.
- Do not drive or do anything that requires mental focus until you know how Donil Tablet affects you.
- Be cautious while taking this medicine if you suffer from peptic ulcer as it may cause vomiting, stomach bleeding, stomach pain, or discomfort.
- Inform your doctor if you develop muscle tremors, especially if you have Parkinson’s disease.
- Inform your doctor if you experience seizures or convulsions while taking this medicine.
- You have been prescribed Donil Tablet to slow down the progression of Alzheimer's disease.
- It does not cure Alzheimer's disease but may help improve brain function and ability to do daily activities.
- Take it with or without food, preferably at night before going to bed.
- It may cause diarrhea, nausea, and vomiting. Drink plenty of fluids to keep yourself hydrated while taking Donil Tablet.
- Monitor your body weight regularly as both Donil Tablet and Alzheimer's disease can cause weight loss.
- Do not drive or do anything that requires mental focus until you know how Donil Tablet affects you.
- Be cautious while taking this medicine if you suffer from peptic ulcer as it may cause vomiting, stomach bleeding, stomach pain, or discomfort.
- Inform your doctor if you develop muscle tremors, especially if you have Parkinson’s disease.
- Inform your doctor if you experience seizures or convulsions while taking this medicine.
Fact Box
Chemical Class
N- benzylpiperidines
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Cholinesterase Inhibitors
Interaction with drugs
Taking Donil with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Carbachol may increase the effect of Donepezil.
Watch out for symptoms such as drowsiness, impaired movement, tiredness, nausea, palpitations, or numbness, and consult your doctor if you experience them. They may adjust the dose
If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.
If used together, Donepezil may interrupt with the efficacy of
If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Bethanechol may increase the effect of Donepezil.
If concurrent use is essential, please consult your doctor. They may monitor your treatment and adjust the doses as per the observations.
If used together, Clomipramine may oppose
Patient concerns
FAQs
Why is Donil Tablet taken at night?
Donil Tablet is recommended to be taken before going to bed to reduce gastrointestinal side effects or nausea, which is commonly seen in some patients in the first few weeks of treatment.
Do the gastrointestinal side effects due to Donil Tablet persist for a long time?
Gastrointestinal side effects may appear during the first few weeks of treatment with Donil Tablet. This can be minimized by taking Donil Tablet at bedtime and with food. Generally, these side effects are mild and disappear within a few weeks with continued treatment.
How long does it take for Donil Tablet to start working?
Within the first month of treatment with Donil Tablet, you may experience improvement in thinking and remembering (cognitive effect). However, it may take about 12 weeks to see the full benefits.
When should Donil Tablet be stopped?
Do not stop Donil Tablet without consulting your doctor. This medicine only helps to control your condition but does not cure it. Therefore, it may take several weeks to show benefits, so do not be discouraged if you do not see an improvement straight away. But, in case your condition starts worsening and you feel that it is no longer helping you, then you should consult a doctor before stopping it.
For how long does Donil Tablet stay in your system?
Donil Tablet gets removed from the body very slowly. It takes about two weeks or more for Donil Tablet to be completely removed from the system.
Does Donil Tablet cause depression?
No, Donil Tablet does not cause depression. If you are experiencing symptoms, then it could be due to existing Alzheimer’s disease.
What if I take more than the prescribed dose of Donil Tablet?
Taking more than the recommended dose of Donil Tablet may cause vomiting, increased sweating or saliva production, slow heartbeat, dizziness, difficulty in breathing, seizures or fits, weakness, low blood pressure, convulsions, and inability to control your bowel motions or passing of urine (incontinence). You should seek immediate help from a doctor or emergency service of a nearby hospital.
I have been taking indomethacin for arthritis. Can I take Donil Tablet?
Donil Tablet does not interfere with the working of indomethacin, but indomethacin individually increases the risk of stomach bleeding when taken for a long time. Therefore, if you experience any symptoms of stomach bleeding, consult your doctor immediately.
Does Donil Tablet cause hallucinations?
Hallucinations are a common side effect of Donil Tablet, though not everyone is affected. Other common psychiatric side effects include agitation, aggressive behavior, nightmares, and abnormal dreams.
Who should not take Donil Tablet?
Donil Tablet should not be taken by patients who have hypersensitivity to Donil Tablet hydrochloride, piperidine derivatives, or to any active ingredients used in the medicine. Also, it should not be used during pregnancy unless clearly necessary.
Can it cause insomnia?
Yes, insomnia (sleeplessness) is a common side effect of Donil Tablet. Dizziness and fainting can also be seen as common side effects. Though these side effects are common, they do not occur in everyone.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Stahl SM, editor. Donepezil. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 199-202.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 426-27.
- Donepezil hydrochloride. Woodcliff Lake, New Jersey: Eisai Inc.; 1996 [revised Feb. 2012]. [Accessed 25 Jan. 2019] (online) Available from:
- Donepezil. Hatfield, Hertfordshire: Eisai Ltd.; 1997 [revised 11 May 2018]. [Accessed 25 Jan. 2019] (online) Available from:
- Donepezil hydrochloride. South Ruislip, UK: Aurobindo Pharma - Milpharm Ltd.; 2013 [revised 23 Nov. 2017] [Accessed 19 Jun. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:
- Donepezil hydrochloride [Prescribing Information]. Mahabubnagar, Telangana: Hetero Labs Limited; 2023. [Accessed 20 June 2023]. (online) Available from:
Marketer details
Name: Sigmoid Healthcare Pvt. Ltd.
Address: 10 Gujrat Estate Sanand Road Opp. Mamta Copels Sarkhej Ahmedabad
Country of origin: India
Expires on or after: March, 2026
A licensed vendor partner from your nearest location will deliver Donil Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: March, 2026
A licensed vendor partner from your nearest location will deliver Donil Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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MRP₹126.56 8% OFF
₹117
Inclusive of all taxes
10.0 tablets in 1 strip
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Get by Monday, 15 December
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