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Domone Tablet

Domperidone (10mg)
Genuine
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Domone Tablet is used in the treatment of indigestion, nausea, and vomiting. It increases the movement of food through the stomach and intestines, thereby relieving bloating, fullness, and gastric discomfort.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 08 May 2026 | 03:58 PM (IST)
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General Information

The content is shown in English
Domone Tablet image
Domone Tablet image

Product introduction

Take Domone Tablet half an hour before each meal in the dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should take this medicine until your doctor tells you to stop. Let your doctor know about all other medications you are taking, as some may affect, or be affected by, this medicine.


The most common side effects are headache, dry mouth, and stomach pain. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. It may also cause dizziness. Do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may also cause diarrhea, so it is better to take plenty of fluids while taking this medicine, as it may help to prevent dehydration.


Before taking this medicine, you should let your doctor know if you have liver or kidney problems. You shouldn't take it at the same time as an antacid. Pregnant women should also consult their doctor. You should avoid this medicine if suffering from bleeding ulcers in the stomach.

Benefits of Domone Tablet

Treatment of Indigestion
Indigestion means discomfort of mainly the upper part of your stomach which may also have other symptoms such as stomach pain, bloating, feeling full, etc. Domone Tablet improves the movement of food in your stomach and gut (intestine). This relieves these symptoms and helps in the proper digestion of food.

Take Domone Tablet as prescribed by the doctor. Think about what foods trigger indigestion and try to avoid them; eat smaller, more frequent meals; try to lose weight if you are overweight, and try to find ways to relax. Do not eat within 3-4 hours of going to bed.

Side effects of Domone Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Domone
  • Headache
  • Diarrhea
  • Dryness in mouth
  • Stomach pain

How to use Domone Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Domone Tablet is to be taken on an empty stomach.

How Domone Tablet works

Domone Tablet is a prokinetic. It works on the region in the brain that controls vomiting. It also acts on the upper digestive tract to increase the movement of the stomach and intestines, allowing food to move more easily through the stomach.

Quick tips

  • Domone Tablet helps relieve nausea, vomiting, and indigestion.
  • It should be taken before meals as per the dose and duration prescribed by your doctor.
  • It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
  • Avoid consuming alcohol when taking Domone Tablet as it may cause excessive drowsiness.
  • Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
  • Inform your doctor if you get watery diarrhea, fever, or stomach pain that does not go away.
  • Do not take it for longer than 7 days without consulting your doctor.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Domone Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Information regarding the use of Domone Tablet during pregnancy is not available. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Domone Tablet during breastfeeding is not available. Please consult your doctor.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Domone Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CAUTION
Domone Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

UNSAFE
Domone Tablet is unsafe to use in patients with liver disease and should be avoided.

Interaction with drugs

Taking Domone with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Chloroquine (Oral Route)

Do not consume Chloroquine with Domperidone. Concomitant use may affect heart rhythm.
Life-threatening

Ciprofloxacin (Oral Route)

Do not consume Ciprofloxacin with Domperidone.
Life-threatening

Hydroxyzine (Oral Route)

Do not consume Hydroxyzine with Domperidone.
Life-threatening

Ciprofloxacin (Injection Route)

Do not consume Ciprofloxacin with Domperidone.
Life-threatening

Amiodarone (Oral Route)

Do not consume Domperidone with Amiodarone.

Frequently asked questions

Domone Tablet is used for the treatment of nausea (feeling sick) and vomiting as and when recommended by your doctor.
Domone Tablet is not an over-the-counter (OTC) medicine and it is not advisable to take it without a prescription.
Weight gain has not been reported with the use of Domone Tablet. If you notice any abnormal weight gain while using Domone Tablet, please talk to your doctor.
The increase in blood pressure is generally not seen with the use of Domone Tablet. But if you experience an increase in blood pressure while using Domone Tablet, please consult your doctor.
Domone Tablet is not indicated or recommended for treating morning sickness. Please consult your doctor if you plan to take any medicine for treating morning sickness.
The use of Domone Tablet with antibiotics like erythromycin, levofloxacin, moxifloxacin, spiramycin, and some antifungals is not recommended. Please consult your doctor before using any antibiotics with Domone Tablet.
Yes, Domone Tablet can be taken with doxycycline. No drug-drug interactions have been reported. However, please consult your doctor before taking Domone Tablet with doxycycline.
Yes, Domone Tablet can be taken with omeprazole. No drug-drug interactions have been reported. However, interactions may occur. Please consult your doctor before using the two medicines together.
Yes, Domone Tablet can be taken with amoxicillin. No drug-drug interactions have been reported. However, please consult your doctor before taking Domone Tablet with amoxicillin.
Yes, Domone Tablet can be taken with paracetamol. No drug--drug interactions have been reported. However, interactions may occur. Please consult your doctor.
Yes. Domone Tablet is safe if used at prescribed doses for the prescribed duration as advised by the physician/ doctor.
Domone Tablet is indicated for use in motion sickness. Please consult your doctor before using Domone Tablet for motion sickness as it must be used in the dose and duration as advised by your doctor.
No, Domone Tablet is not an antibiotic. Domone Tablet is an anti-emetic that is used to treat nausea (feeling sick) and vomiting (being sick).
Drowsiness has been reported as one of the rare side effects with Domone Tablet. Please talk to your doctor if you experience excessive drowsiness while taking Domone Tablet.
Yes, Domone Tablet can increase milk secretion also known as galactorrhea. This is an uncommon side effect of Domone Tablet. Talk to your doctor if you are experiencing this side effect while taking this medicine.
Domone Tablet can cause some uncommon gastrointestinal side effects like regurgitation, appetite disorder, and heartburn, diarrhea. However, bloating (gas) has not been reported as a side effect with Domone Tablet.
Domone Tablet has not been reported to cause hair loss. Please consult your doctor in case you experience excessive hair loss while taking Domone Tablet.
Domone Tablet is not indicated to treat constipation. Please talk to your doctor regarding its use.
Domone Tablet may be associated with an increased risk of heartbeat problems and heart attacks. This risk may be more likely in those over 60 years old or taking higher doses. The risk also increases when Domone Tablet is given together with other medicines. Please share your medical history with your doctor if you are prescribed Domone Tablet.
Yes, Domone Tablet has been seen to cause constipation as a side effect. Consult your doctor if you experience excessive constipation while using Domone Tablet.
Domone Tablet is an anti-emetic that is used to treat nausea (feeling sick) and vomiting (being sick). It is not indicated to treat bloating (gas). Please consult your doctor before using this medicine.

Fact Box

Chemical Class

Benzimidazoles

Habit Forming

No

Therapeutic Class

GASTRO INTESTINAL

Action Class

Dopamine D2 Receptor Antagonists- Prokinetic Agents

References

  1. McQuaid KR. Drugs Used in the Treatment of Gastrointestinal Diseases. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1078.
  2. Domperidone and domperidone maleate. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2003 [revised 14 Nov. 2017]. [Accessed 24 Jan. 2019] (online) Available from:
  3. International BreastFeeding Center. Domperidone. [Accessed 28 Mar. 2019] (online) Available from:
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:
  5. Domperidone [Summary of Product Characteristics]. Ahmedabad, Gujarat: Cadila Pharmaceuticals Limited; 2016.
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Auspharma Private Limited
Address: 10-3-316/A/2, Masab Tank Hyderabad Hyderabad TG 500028 India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Domone Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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